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Diversity of Selenium Functions in Health and Disease, 


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Название:  Diversity of Selenium Functions in Health and Disease
ISBN: 9780367377502
Издательство: Taylor&Francis
Классификация:

ISBN-10: 0367377500
Обложка/Формат: Paperback
Страницы: 432
Вес: 1.76 кг.
Дата издания: 27.09.2019
Язык: English
Размер: 234 x 155 x 23
Читательская аудитория: Tertiary education (us: college)
Основная тема: Toxicology
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Named after Selene, Greek goddess of the moon, selenium (Se) has moved has moved from being thought of as a toxicant to being considered an essential nutrient with the potential to reduce cancer risk in the span of seven decades. Diversity of Selenium Functions in Health and Disease focuses on current knowledge of aspects of Se research relevant to its medical use, and particularly to chemoprevention of cancer. It covers how Se is integrated into selenoproteins, selenium compounds with individual functions and dual functions, and unexpected links to Se such as with diabetes. The text ends with a discussion of polymorphisms and mutations in genes of selenoproteins.

The chapters elucidate why studies undertaken to prevent diseases with selenium ended with disappointing outcomes and often with the opposite result, i.e. disease promotion. They show that benefit, failure, or side effects depend on:

  • The chemical form and dose of selenium
  • The selenium status of the individual ingesting selenium
  • The capacity of selenium form to serve as a source for selenoprotein biosynthesis
  • The function of selenoproteins reacting to a change in the selenium status
  • The stage of the disease (mainly cancer) at the time point of intervention
  • The genetic background of individuals to be treated

Bringing together the accumulated evidence regarding selenium biochemistry, the book covers aspects not found in available general monographs. The narrow focus on medical uses of Se helps resolve the present confusion about potential benefits and hazards of selenium in human health. The book gives you a solid scientific basis for optimum use of selenium in preventing or treating human diseases and answering the questions: Why is selenium essential? How much is required? What are the health consequences of low selenium and can selenium reduce cancer risk?



Selenium research for environment and human health: perspectives, technologies and advancements

Название: Selenium research for environment and human health: perspectives, technologies and advancements
ISBN: 1138390143 ISBN-13(EAN): 9781138390140
Издательство: Taylor&Francis
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Цена: 163330.00 T
Наличие на складе: Невозможна поставка.
Описание: This proceedings volume brings together peer-reviewed extended abstracts prepared by contributors from academia, industry, and governments from over 29 countries representing a multitude of disciplines. They share their extraordinary new knowledge on selenium in the peer-reviewed texts contained within this book.

Selenium: Sources, Functions & Health Effects

Автор: Chinatsu Aomori, Megumi Hokkaido
Название: Selenium: Sources, Functions & Health Effects
ISBN: 1619420619 ISBN-13(EAN): 9781619420618
Издательство: Nova Science
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Цена: 205910.00 T
Наличие на складе: Невозможна поставка.
Описание: During World War II, Academy Award-winning director Frank Capra made propaganda films for the U.S. Government, such as Prelude to War, The Nazis Strike, The Battle of Britain, War Comes to America and The Negro Soldier. This analyses the cinematic and thematic techniques Capra employed in these films, linking them to the techniques and ideology of the director`s popular mainstream narrative films.

Selenium in Biology and Human Health

Автор: Raymond F. Burk
Название: Selenium in Biology and Human Health
ISBN: 1461275970 ISBN-13(EAN): 9781461275978
Издательство: Springer
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Цена: 97820.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Selenium plays a fascinating and still poorly understood role in the function of living cells and therefore in human health.

Selenium and Tellurium Chemistry

Автор: J. Derek Woollins; Risto Laitinen
Название: Selenium and Tellurium Chemistry
ISBN: 3642436986 ISBN-13(EAN): 9783642436987
Издательство: Springer
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Цена: 148010.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In addition to updating the reader on recent theoretical and practical research into the synthesis, structure and bonding of novel selenium and tellurium compounds, this book outlines applications in biological systems, materials sience and organic synthesis.

Selenium

Автор: Hatfield
Название: Selenium
ISBN: 3319412817 ISBN-13(EAN): 9783319412818
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field. Evidence from epidemiology and veterinary science supports the essential role of selenium in (human) health, but its split personality in both preventing and supporting cancer and also in promoting insulin resistance has become more clearly defined. The pivotal role of glutathione peroxidase 4 in a new process of programmed cell death, ferroptosis, brings new impetus to the field. Recently defined mutations in selenoprotein and biosynthesis factor genes have been identified in patients, and the resulting disorders further emphasize the significance of selenoproteins in human health. The mechanism of selenoprotein biosynthesis, the functions of selenoproteins, and the roles of dietary selenium have been further elucidated, and new regulatory mechanisms involving selenoproteins discovered. The book, therefore, covers the breadth of current selenium research. With up-to-date chapters written by leaders in their fields, it serves as an invaluable resource for novices as well as specialists.

Selenium

Автор: Michalke
Название: Selenium
ISBN: 3030070263 ISBN-13(EAN): 9783030070267
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more.

Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

Название: Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
ISBN: 303897692X ISBN-13(EAN): 9783038976929
Издательство: Неизвестно
Рейтинг:
Цена: 54390.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Gene cloning and sequence has provided the opportunity to identify and characterize the functional role of biomarkers expressed in and on tumor cells and the surrounding microenvironment. Molecular and immunologic heterogeneity of cells in the tumor microenvironment contributes to instability, enhanced angiogenesis, and drug resistance of the tumor cell. Since tumor cells are the ultimate therapeutic targets for drugs and therapy development, the tumor microenvironment that regulates the growth and the delivery of effective drug concentrations to tumor cells is the gatekeeper. Thus, to have a significant impact on the overall survival and cure of patients with advanced cancer, the stabilization of the tumor microenvironment should be the initial treatment, followed by treatment that targets and kills tumor cells.

Antiangeogenic therapies hold considerable promise in the treatment of a subset of cancer patients and are reported to have a significant impact on the stabilization of the tumor microenvironment. More recently, selenium-containing molecules, such as se-metylselenocysteine, seleno-L-methionine, and selenized yeast, among others, have been shown to target and modulate biomarkers associated with tumor cells and the tumor microenvironment. The effects are selenium type-, dose-, and schedule-dependent. The pleiotropic actions of selenium are necessary for tumor cell sensitization, and synergy with mechanism-based combinations. This Special Issue is devoted to highlighting evidence for the potential role of specific types, doses, and schedules of selenium alone and in combination with mechanism-based biologic and cytotoxic therapies for the prevention and treatment of cancer and related diseases. The collection of contributions should provide a comprehensive overview of the pharmacology, metabolism, and delineation of the pleiotropic action of different types of selenium molecules, relevant to the use of selenium as a potential modulator of the therapeutic efficacy and toxicity of biologic and cytotoxic therapies for cancer and related diseases. The pleiotropic action of specific types of selenium, doses, and schedule, as a selective and efficacious modulator of genetic, immunologic, and epigenetic biomarkers, should stimulate expanded preclinical research that could ultimately impact the development of new and novel approaches for the treatment of cancer.


Selenium and Tellurium Reagents: In Chemistry and Materials Science

Автор: Laitinen Risto, Oilunkaniemi Raija
Название: Selenium and Tellurium Reagents: In Chemistry and Materials Science
ISBN: 3110527944 ISBN-13(EAN): 9783110527940
Издательство: Walter de Gruyter
Цена: 111510.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Selenium and Tellurium Reagents provides an in-depth overview of recent advances on the chemistry of these elements. Written by internationally recognized experts, it gives insight into the synthesis, structure, analysis and mechanistic studies of these compounds. The book is organized into four parts which reflect the applications of Se and Te reagents in four areas: inorganic chemistry, organic chemistry, materials science and biochemistry.

Selenium in Biology and Medicine

Автор: Albrecht Wendel
Название: Selenium in Biology and Medicine
ISBN: 3642744230 ISBN-13(EAN): 9783642744235
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
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Описание: Sponsored by the International Selenium Organizing Committee in cooperation with the Deutsche Forschungsgemeinschaft

Selenium

Автор: Dolph L. Hatfield; Marla J. Berry; Vadim N. Gladys
Название: Selenium
ISBN: 1489994459 ISBN-13(EAN): 9781489994455
Издательство: Springer
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Цена: 156720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As with the two prior volumes in this series, this book examines the latest research in this rapidly developing field, analyzing the health benefits of selenium as well as focusing in particular on the way in which it relates to the biochemistry of proteins.

Selenium

Автор: Dolph L. Hatfield
Название: Selenium
ISBN: 1461356393 ISBN-13(EAN): 9781461356394
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As discussed in this book, a large body of evidence indicates that selenium is a cancer chemopreventive agent. Selenocysteine utilizes a specific tRNA, a specific elongation factor, a specific set of signals, and the codeword, UGA, for its cotranslational insertion into protein.

Biochemistry of Selenium

Автор: Raymond Shamberger
Название: Biochemistry of Selenium
ISBN: 1468443151 ISBN-13(EAN): 9781468443158
Издательство: Springer
Рейтинг:
Цена: 113190.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.


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