Methods for Studying Nucleic Acid/Drug Interactions, 

Автор: Likhtenshtein Gertz
Название: Electron Spin Interactions in Chemistry and Biology: Fundamentals, Methods, Reactions Mechanisms, Magnetic Phenomena, Structure Investigation
ISBN: 3319816349 ISBN-13(EAN): 9783319816340
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book presents the versatile and pivotal role of electron spin interactions in nature. It provides the background, methodologies and tools for basic areas related to spin interactions, such as spin chemistry and biology, electron transfer, light energy conversion, photochemistry, radical reactions, magneto-chemistry and magneto-biology.

Автор: Daviter Tina, Johnson Christopher M., McLaughlin Stephen H.
Название: Protein-Ligand Interactions: Methods and Applications
ISBN: 1071611968 ISBN-13(EAN): 9781071611968
Издательство: Springer
Цена: 121110.00 T
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Описание: This third edition provides new and updated chapters detailing a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins with their natural ligands, drugs or other binding partners.

Автор: Daviter Tina, Johnson Christopher M., McLaughlin Stephen H.
Название: Protein-Ligand Interactions: Methods and Applications
ISBN: 1071611992 ISBN-13(EAN): 9781071611999
Издательство: Springer
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Цена: 121110.00 T
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Описание: This third edition provides new and updated chapters detailing a complete introduction to common and emerging procedures for characterizing the interactions of individual proteins with their natural ligands, drugs or other binding partners.

Автор: Ogris Manfred, Oupicky David
Название: Nanotechnology for Nucleic Acid Delivery: Methods and Protocols
ISBN: 1493959328 ISBN-13(EAN): 9781493959327
Издательство: Springer
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Цена: 102480.00 T
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Описание: This Methods in Molecular Biology (TM) series book covers nanoparticulate delivery of nucleic acids in terms of biosafety, particle synthesis as well as its application in cell culture. Includes materials and reagents, protocols, notes on troubleshooting and more.

Автор: Marx
Название: Molecular Beacons: Signalling Nucleic Acid Probes, Methods, and Protocols
ISBN: 1617377260 ISBN-13(EAN): 9781617377266
Издательство: Springer
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Цена: 121110.00 T
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Описание: From probe design to applications in clinical settings, this book provides a diverse set of instructive examples, guided by experts in the field who offer easy-to-follow experimentals.

Автор: Daphne A. Roe
Название: Diet and Drug Interactions
ISBN: 940116049X ISBN-13(EAN): 9789401160490
Издательство: Springer
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Цена: 87070.00 T
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Описание: When we learn from a patient, clinician, or medical record that a drug has been discontinued, it is logical to ask why. Drugs may also produce nutritional deficiencies, especially in a patient whose diet is marginal in those nutrients depleted by the particular drug.

Автор: K. Sandy Pang; A. David Rodrigues; Raimund M. Pete
Название: Enzyme- and Transporter-Based Drug-Drug Interactions
ISBN: 1441908390 ISBN-13(EAN): 9781441908391
Издательство: Springer
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Цена: 217680.00 T
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Описание: This proceedings volume from the annual meeting of The American Association of Pharmaceutical Scientists, held November 2007, examines enzyme- and transporter-based DDIs that impact the absorption and disposition of drugs and impact on adverse outcomes.

Автор: Patrick F. D`Arcy; James C. McElnay; Peter G. Well
Название: Mechanisms of Drug Interactions
ISBN: 3642646581 ISBN-13(EAN): 9783642646584
Издательство: Springer
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Цена: 121890.00 T
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Описание: With contributions by numerous experts

Автор: Ehlert Frederick J
Название: Affinity And Efficacy: The Components Of Drug-Receptor Interactions
ISBN: 9814322563 ISBN-13(EAN): 9789814322560
Издательство: World Scientific Publishing
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Цена: 253440.00 T
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Описание: The interaction of a drug with a receptor encodes a vector of information having components of affinity and efficacy. This book describes how to analyze various responses to estimate the affinity and efficacy components of the initial drug-receptor interaction.

Автор: K. Sandy Pang; A. David Rodrigues; Raimund M. Pete
Название: Enzyme- and Transporter-Based Drug-Drug Interactions
ISBN: 1489994890 ISBN-13(EAN): 9781489994899
Издательство: Springer
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Цена: 191550.00 T
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Описание: This proceedings volume from the annual meeting of The American Association of Pharmaceutical Scientists, held November 2007, examines enzyme- and transporter-based DDIs that impact the absorption and disposition of drugs and impact on adverse outcomes.

Автор: Tony K.L. Kiang; Kyle John Wilby; Mary H.H. Ensom
Название: Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials
ISBN: 3319105264 ISBN-13(EAN): 9783319105260
Издательство: Springer
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Цена: 60550.00 T
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Описание: This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings. Current limitations and gaps in the literature are summarized, and potential future research directions / experimentations are also suggested.  In addition to the main objective to review the available clinical pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antimalarial drugs on the market today (i.e. chloroquine, amodiaquine, sulfadoxine, pyrimethamine, mefloquine, artemisinin, artemether, artesunate, dihydroartemisinin, artemotil, lumefantrine, primaquine, atovaquone, proguanil, piperaquine and quinine), this book also provides succinct chapter summaries on the epidemiology of malaria infection, diagnosis and therapeutics, in vivo pharmacology and chemistry, preclinical pharmacology, in vitro pharmacodynamics, in vitro reaction phenotyping, and in vitro drug-drug interaction data associated with the identified antimalarial drugs.

Автор: Tony K.L. Kiang; Kyle John Wilby; Mary H.H. Ensom
Название: Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials
ISBN: 3319381938 ISBN-13(EAN): 9783319381930
Издательство: Springer
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Цена: 55890.00 T
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Описание: Introduction.- Pharmacology of Recommended Antimalarial Agents.- Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials.- Pharmacokinetic Drug Interactions Affecting Antimalarials.- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Drugs.- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials.- Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions.- Limitations, Future Directions, and Conclusions.