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Label-Free Monitoring of Cells in vitro, Joachim Wegener


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Цена: 186330.00T
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При оформлении заказа до: 2025-07-28
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Автор: Joachim Wegener
Название:  Label-Free Monitoring of Cells in vitro
ISBN: 9783030324322
Издательство: Springer
Классификация:






ISBN-10: 303032432X
Обложка/Формат: Hardcover
Страницы: 277
Вес: 0.61 кг.
Дата издания: 2019
Серия: Bioanalytical Reviews
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 80 tables, color; 80 illustrations, color; xi, 277 p. 80 illus. in color.; 80 tables, color; 80 illustrations, color; xi, 277 p. 80 illus. in color.
Размер: 234 x 156 x 18
Читательская аудитория: Professional & vocational
Основная тема: Chemistry
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book is dedicated to label-free, non-invasive monitoring of cell-based assays and it comprises the most widely applied techniques. Each approach is described and critically evaluated by an expert in the field such that researchers get an overview on what is possible and where the limitations are. The book provides the theoretical basis for each technique as well as the most successful and exciting applications.Label-free bioanalytical techniques have been known for a long time as valuable tools to monitor adsorption processes at the solid-liquid interface in general – and biomolecular interaction analysis (BIA) in particular. The underlying concepts have been progressively transferred to the analysis of cell-based assays. The strength of these approaches is implicitly given with the name label-free: the readout is independent of any label, reagent or additive that contaminates the system under study and potentially affects its properties. Thus, label-free techniques provide an unbiased analytical perspective in the sense that the sample is not manipulated by additives but pure. They are commonly based on physical principles and read changes in integral physical properties of the sample like refractive index, conductivity, capacitance or elastic modulus to mention just a few. Even though it is not implied in the name, label-free approaches usually monitor the cells under study non-invasively meaning that the amplitude of the signal (e.g. electric field strength, mechanical elongation) that is used for the measurement is too low to interfere or affect. In contrast to label-based analytical techniques that are commonly restricted to a single reading at a predefined time point, label-free approaches allow for a continuous observation so that the dynamics of the biological system or reaction become accessible.

Дополнительное описание: Impedance-Based Assays Along the Life Span of Adherent Mammalian Cells In Vitro: From Initial Adhesion to Cell Death.- Transistor-Based Impedimetric Monitoring of Single Cells.- Label-Free Monitoring of 3D Tissue Models via Electrical Impedance Spectrosco


Label-Free Biosensing

Автор: Michael J. Sch?ning; Arshak Poghossian
Название: Label-Free Biosensing
ISBN: 3030091732 ISBN-13(EAN): 9783030091736
Издательство: Springer
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Цена: 354040.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with:· semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors· impedimetric biosensors using planar and 3D electrodes· nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors· electrochemical biosensors using molecularly imprinted polymers· biomimetic sensors based on acoustic signal transduction· enzyme logic systems and digital biosensors based on the biocomputing concept· heat-transfer as a novel transducer principle· ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices

Intravascular Imaging and Computer Assisted Stenting, and Large-Scale Annotation of Biomedical Data and Expert Label Synthesis

Автор: M. Jorge Cardoso; Tal Arbel; Su-Lin Lee; Veronika
Название: Intravascular Imaging and Computer Assisted Stenting, and Large-Scale Annotation of Biomedical Data and Expert Label Synthesis
ISBN: 3319675338 ISBN-13(EAN): 9783319675336
Издательство: Springer
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Цена: 46570.00 T
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Описание:

This book constitutes the refereed joint proceedings of the 6th Joint International Workshop on Computing and Visualization for Intravascular Imaging and Computer Assisted Stenting, CVII-STENT 2017, and the Second International Workshop on Large-Scale Annotation of Biomedical Data and Expert Label Synthesis, LABELS 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017.

The 6 full papers presented at CVII-STENT 2017 and the 11 full papers presented at LABELS 2017 were carefully reviewed and selected. The CVII-STENT papers feature the state of the art in imaging, treatment, and computer-assisted intervention in the field of endovascular interventions. The LABELS papers present a variety of approaches for dealing with few labels, from transfer learning to crowdsourcing.


Geospace Electromagnetic Waves and Radiation

Автор: LaBelle James W. , Treumann Rudolf A.
Название: Geospace Electromagnetic Waves and Radiation
ISBN: 3540300503 ISBN-13(EAN): 9783540300502
Издательство: Springer
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Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The contributions gathered in this volume provide introductions to current problems in geospace electromagnetic radiation, guides to the associated literature and tutorial reviews of the relevant space physics.Students and scientists working on various aspects of the terrestrial aurora or magnetospheric and near-Earth heliospheric high-frequency waves will find this volume an indispensable companion for their studies.

Phosphate Labeling and Sensing in Chemical Biology

Автор: Henning Jacob Jessen
Название: Phosphate Labeling and Sensing in Chemical Biology
ISBN: 3319603566 ISBN-13(EAN): 9783319603568
Издательство: Springer
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Цена: 232910.00 T
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Описание: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes.

Learning with Partially Labeled and Interdependent Data

Автор: Massih-Reza Amini; Nicolas Usunier
Название: Learning with Partially Labeled and Interdependent Data
ISBN: 331935390X ISBN-13(EAN): 9783319353906
Издательство: Springer
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Цена: 74530.00 T
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Описание: This book develops two key machine learning principles: the semi-supervised paradigm and learning with interdependent data.

Proximity Labeling

Автор: Murat Sunbul; Andres J?schke
Название: Proximity Labeling
ISBN: 1493995367 ISBN-13(EAN): 9781493995363
Издательство: Springer
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Цена: 167700.00 T
Наличие на складе: Поставка под заказ.
Описание: This book provides detailed protocols and untold tips and tricks regarding the most well-known examples of proximity labeling methods, in which the protein of interest is genetically fused to or labeled with an enzyme that can generate short-lived reactive species to non-specifically label molecules within a certain radius of up to twenty nanometers. Beginning with peroxidase-based proximity labeling methods, the volume continues with BioID, proximity labeling methods that describe the proximity ligation assay to detect RNA-DNA interactions, UV cross-linking to demonstrate RNA-protein interactions, and how chemical and enzymatic reactivities can be improved upon DNA-DNA and protein-protein interactions, as well as “proximity-induced self-labeling,” where the radius of labeling is zero. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Proximity Labeling: Methods and Protocols serves as an ideal guide for researchers exploring the crucial roles that proximity-driven reactions play in biological systems.

Geospace Electromagnetic Waves and Radiation

Автор: James W. LaBelle; R.A. Treumann
Название: Geospace Electromagnetic Waves and Radiation
ISBN: 3642067603 ISBN-13(EAN): 9783642067600
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The contributions gathered in this volume provide introductions to current problems in geospace electromagnetic radiation, guides to the associated literature and tutorial reviews of the relevant space physics.

Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors

Автор: Maximilian Oberleitner
Название: Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors
ISBN: 3319832794 ISBN-13(EAN): 9783319832791
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Поставка под заказ.
Описание:

This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research.

The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design
principles and elucidates the boundary conditions of the new sensors.


Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors

Автор: Maximilian Oberleitner
Название: Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors
ISBN: 3319453831 ISBN-13(EAN): 9783319453835
Издательство: Springer
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Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Objectives.- Methods & Instrumentation.- MQCM: Multiple Cytomechanic Sensing.- QCM-ECIS: Combined Viscoelastic and Dielectric Sensing of Cells.- QCM-OCS: Optochemical Sensing of Temperature and pO2 in the Cell Surface Junction.- Summary.- Appendix.

Label-Free Biosensing

Автор: Sch?ning
Название: Label-Free Biosensing
ISBN: 3319752197 ISBN-13(EAN): 9783319752198
Издательство: Springer
Рейтинг:
Цена: 354040.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field.

Highlights of the subjects covered include label-free biosensing with:

- semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors

- impedimetric biosensors using planar and 3D electrodes

- nanocavity and solid-state nanopore devices

- carbon nanotube and graphene/graphene oxide biosensors

- electrochemical biosensors using molecularly imprinted polymers

- biomimetic sensors based on acoustic signal transduction

- enzyme logic systems and digital biosensors based on the biocomputing concept

- heat-transfer as a novel transducer principle

- ultrasensitive surface plasmon resonance biosensors

- magnetic biosensors and magnetic imaging devices


Label-Free Super-Resolution Microscopy

Автор: Vasily Astratov
Название: Label-Free Super-Resolution Microscopy
ISBN: 3030217213 ISBN-13(EAN): 9783030217211
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
Наличие на складе: Невозможна поставка.
Описание: This book presents the advances in super-resolution microscopy in physics and biomedical optics for nanoscale imaging. In the last decade, super-resolved fluorescence imaging has opened new horizons in improving the resolution of optical microscopes far beyond the classical diffraction limit, leading to the Nobel Prize in Chemistry in 2014. This book represents the first comprehensive review of a different type of super-resolved microscopy, which does not rely on using fluorescent markers. Such label-free super-resolution microscopy enables potentially even broader applications in life sciences and nanoscale imaging, but is much more challenging and it is based on different physical concepts and approaches. A unique feature of this book is that it combines insights into mechanisms of label-free super-resolution with a vast range of applications from fast imaging of living cells to inorganic nanostructures. This book can be used by researchers in biological and medical physics. Due to its logically organizational structure, it can be also used as a teaching tool in graduate and upper-division undergraduate-level courses devoted to super-resolved microscopy, nanoscale imaging, microscopy instrumentation, and biomedical imaging.

Large-Scale Annotation of Biomedical Data and Expert Label Synthesis and Hardware Aware Learning for Medical Imaging and Computer Assisted Intervention

Автор: Luping Zhou; Nicholas Heller; Yiyu Shi; Yiming Xia
Название: Large-Scale Annotation of Biomedical Data and Expert Label Synthesis and Hardware Aware Learning for Medical Imaging and Computer Assisted Intervention
ISBN: 3030336417 ISBN-13(EAN): 9783030336417
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

4th International Workshop on Large-Scale Annotation of Biomedical Data and Expert Label Synthesis (LABELS 2019).- Comparison of active learning strategies applied to lung nodule segmentation in CT scans.- Robust Registration of Statistical Shape Models for Unsupervised Pathology Annotation.- XiangyaDerm: A Clinical Image Dataset of Asian Race for Skin Disease Aided Diagnosis.- Data Augmentation based on Substituting Regional MRI Volume Scores.- Weakly supervised segmentation from extreme points.- Exploring the Relationship between Segmentation Uncertainty, Segmentation Performance and Inter-observer Variability with Probabilistic Networks.- DeepIGeoS-V2: Deep Interactive Segmentation of Multiple Organs from Head and Neck Images with Lightweight CNNs.- The Role of Publicly Available Data in MICCAI Papers from 2014 to 2018.- First International Workshop on Hardware Aware Learning for Medical Imaging and Computer Assisted Intervention (HAL-MICCAI 2019).- Hardware Acceleration of Persistent Homology Computation.- Deep Compressed Pneumonia Detection for Low-Power Embedded Devices.- D3MC: A Reinforcement Learning based Data-driven Dyna Model Compression.- An Analytical Method of Automatic Alignment for Electron Tomography.- Fixed-Point U-Net Quantization for Medical Image Segmentation.- Second International Workshop on Correction of Brainshift with Intra-Operative Ultrasound (CuRIOUS 2019).- Registration of ultrasound volumes based on Euclidean distance transform.- Landmark-based evaluation of a block-matching registration framework on the RESECT pre- and intra-operative brain image data set.- Comparing deep learning strategies and attention mechanisms of discrete registration for multimodal image-guided interventions.




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