Bioinformatics and Drug Discovery, Richard S. Larson; Tudor I. Oprea
Автор: Larson Richard S. Название: Bioinformatics and Drug Discovery ISBN: 1588293467 ISBN-13(EAN): 9781588293466 Издательство: Springer Рейтинг: Цена: 172350.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.
Автор: Loging Название: Bioinformatics and Computational Biology in Drug Discovery and Development ISBN: 0521768004 ISBN-13(EAN): 9780521768009 Издательство: Cambridge Academ Рейтинг: Цена: 61240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Providing a comprehensive overview of the drug discovery and development pipeline, this book focuses on the integral role that computational biology methods play in this process. Covering technological advances and their relation to drug developmental processes, readers are exposed to new methods of discovery utilising the available technology.
This book reviews the advances and challenges of structure-based drug design in the preclinical drug discovery process, addressing various diseases, including malaria, tuberculosis and cancer. Written by internationally recognized researchers, this edited book discusses how the application of the various in-silico techniques, such as molecular docking, virtual screening, pharmacophore modeling, molecular dynamics simulations, and residue interaction networks offers insights into pharmacologically active novel molecular entities. It presents a clear concept of the molecular mechanism of different drug targets and explores methods to help understand drug resistance. In addition, it includes chapters dedicated to natural-product- derived medicines, combinatorial drug discovery, the CryoEM technique for structure-based drug design and big data in drug discovery.
The book offers an invaluable resource for graduate and postgraduate students, as well as for researchers in academic and industrial laboratories working in the areas of chemoinformatics, medicinal and pharmaceutical chemistry and pharmacoinformatics.
Автор: Loging William T. Название: Bioinformatics and Computational Biology in Drug Discovery a ISBN: 1108461158 ISBN-13(EAN): 9781108461153 Издательство: Cambridge Academ Рейтинг: Цена: 38010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Providing a comprehensive overview of the drug discovery and development pipeline, this book focuses on the integral role that computational biology methods play in this process. Covering technological advances and their relation to drug developmental processes, readers are exposed to new methods of discovery utilising the available technology.
Автор: Wadhwa, Gulshan. Название: Current trends in bioinformatics : ISBN: 981107481X ISBN-13(EAN): 9789811074813 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: This book highlights the latest breakthrough developments in bioinformatics. It presents a series of timely, in-depth reviews, drug clinical trial studies, biodiversity informatics and thematic issues. In addition, it includes insightful reviews on advances in computational molecular/structural biology, which address areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. Innovations in these fields have direct impacts on key issues related to healthcare, medicine, genetic disorders, the development of agricultural products, renewable energy, and environmental protection. Written by respected leaders in the field and covering a wide range of topics involving the integration of biology with computer and information science, the book offers an ideal basis for teaching at the undergraduate and graduate levels. It can also be used for self-instruction by research investigators interested in applying bioinformatics-based analytical methods and information technologists working with academic and industrial laboratories.
Автор: Forsdyke, Donald R. Название: Evolutionary bioinformatics / ISBN: 3319287532 ISBN-13(EAN): 9783319287539 Издательство: Springer Рейтинг: Цена: 177010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Now in its third edition and supplemented with more online material, this book aims to make the "new" information-based (rather than gene-based) bioinformatics intelligible both to the "bio" people and the "info" people.
Автор: David Posada Название: Bioinformatics for DNA Sequence Analysis ISBN: 1617378399 ISBN-13(EAN): 9781617378393 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In Bioinformatics for DNA Sequence Analysis, experts provide practical guidance and troubleshooting advice for the computational analysis of DNA sequences, covering a range of issues and methods that demonstrate the vital relevance bioinformatics has today.
Автор: Andrei L. Osterman; Svetlana Y. Gerdes Название: Microbial Gene Essentiality: Protocols and Bioinformatics ISBN: 1617375292 ISBN-13(EAN): 9781617375293 Издательство: Springer Рейтинг: Цена: 153720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. It contains detailed description of the procedures, discussion of potential difficulties and failures.
Автор: Ronald J.A. Trent Название: Clinical Bioinformatics ISBN: 1617377813 ISBN-13(EAN): 9781617377815 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With the ever-increasing volume of information in clinical medicine, researchers and health professionals need computer-based storage, processing and dissemination. In this book, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance.
Автор: Amita Kashyap; D. Bujamma; Naresh Babu M Название: Bioinformatics of Non Small Cell Lung Cancer and the Ras Proto-Oncogene ISBN: 9814585076 ISBN-13(EAN): 9789814585071 Издательство: Springer Рейтинг: Цена: 60940.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Introduction.- Review of Literature.- Materials and Methods (Tools and Databases).- Flowchart.- Conclusion.-References.
Автор: George Mias Название: Mathematica for Bioinformatics ISBN: 3030101924 ISBN-13(EAN): 9783030101923 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Поставка под заказ. Описание: This book offers a comprehensive introduction to using Mathematica and the Wolfram Language for Bioinformatics. The chapters build gradually from basic concepts and the introduction of the Wolfram Language and coding paradigms in Mathematica, to detailed worked examples derived from typical research applications using Wolfram Language code. The coding examples range from basic sequence analysis, accessing genomic databases, differential gene expression, and machine learning implementations to time series analysis of longitudinal omics experiments, multi-omics integration and building dynamic interactive bioinformatics tools using the Wolfram Language. The topics address the daily bioinformatics needs of a broad audience: experimental users looking to understand and visualize their data, beginner bioinformaticians acquiring coding expertise in providing biological research solutions, and practicing expert bioinformaticians working on omics who wish to expand their toolset to include the Wolfram Language.
Название: Companion diagnostics (cdx) in precision medicine ISBN: 9814800236 ISBN-13(EAN): 9789814800235 Издательство: Taylor&Francis Рейтинг: Цена: 118410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers the technical, historical, clinical, and regulatory aspects of CDx in precision medicine. Clearly, more and more newly developed oncology drugs will require accompanying CDx assays, and this book, with chapters contributed by renowned oncologists.
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