Public Regulation of Tumor Banks, Xavier Bioy

Автор: Glaser, Anthony N.
Название: High-Yield Biostatistics, Epidemiology, and Public Health. 4 ed.
ISBN: 1451130171 ISBN-13(EAN): 9781451130171
Издательство: Lippincott Williams & Wilkins
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Цена: 33400.00 T
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Описание: Provides a review of the biostatistics concepts that are tested in the USMLE Step 1. With tables, diagrams, photographs, and images to clarify important material, this book offers a concentrated, efficient review for both course exams and the USMLE.

Автор: Xavier Bioy
Название: Public Regulation of Tumor Banks
ISBN: 3319905627 ISBN-13(EAN): 9783319905624
Издательство: Springer
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Цена: 93160.00 T
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Описание: The multidisciplinary book assesses the legal and economic uncertainties surrounding the collection, storage, provision and economic development of biological samples (tumors, tissues, cells) and associated personal data related to oncology. Public, partly public and private sector actors in the field of cancer care and research hold collections supported by significant public and social funding. Under certain conditions, particularly in the context of networking (sometimes promoted by public authorities), these collections can also represent major economic assets and scientific resources. However, this involves a number of issues and institutional constraints:legal: the will of the source person; non-pecuniary damage; freedom to establish collections; competence in deciding on their use; legal frameworks for their distribution; desire for return on investment for public institutions, notably in terms of industrial and intellectual property.economic: cost of establishing and running biological resource centres; destroying resources; emerging markets; profit sharing.public health policy choices: prioritisation of therapeutic measures over research (fundamental or clinical trials); conservation of resources; promotion of scientific (and not commercial) value of collections.The establishment, heritage recognition (“patrimonialisation”), development and sharing of these resources thus merit our calling into question present practices and their evolution, as well as the leverage available to public authorities (incentives, legislation, regulation) in a context where norms emerge from professional practice to become widely used in collaborative networks.Filling a gap in the current literature on law and economics, which pays little heed to these specific considerations, this book explores these considerations to bring to light the economic implications of ethical choices and governance issues in the health sector (structural organisation of local, national and European actors in oncology).It is intended for researchers in fields such as law, economics and biomedical sciences, as well as for public policymakers.

Автор: Menashe Bar-Eli
Название: Regulation of Gene Expression in the Tumor Environment
ISBN: 1402083408 ISBN-13(EAN): 9781402083402
Издательство: Springer
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Цена: 213360.00 T
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Описание: The development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. This book discusses different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype.

Автор: Menashe Bar-Eli
Название: Regulation of Gene Expression in the Tumor Environment
ISBN: 9048178495 ISBN-13(EAN): 9789048178490
Издательство: Springer
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Цена: 213360.00 T
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Описание: This volume examines several different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype, shedding further light on the understanding of these complicated processes.

Автор: Mehmet Gunduz, Esra Gunduz
Название: Tumor Suppressor Genes: Functions, Regulation & Health Effects
ISBN: 1628086653 ISBN-13(EAN): 9781628086652
Издательство: Nova Science
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Цена: 267160.00 T
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Описание: Cancer is a devastating disease lacking an exact treatment. Recent advances in genetics and biotechnology have provided a deeper understanding of cancer biology, out of which aberrations in oncogenes and tumour suppresser genes have arisen as important etiological factors. Inactivation of tumour suppresser genes is one of the initial cellular changes that ultimately lead to tumour development. Thus, increasing knowledge about these genes aids in the development of novel therapeutic applications as well as identification of more effective and rapid molecular markers for early diagnosis and prognostic evaluation. This book provides up-to-date information on the structure, function and roles of the main tumour suppresser genes thus far identified. An important addition to the current literature in the field, this book is intended to help instructors for teaching purposes and researchers in the field of cancer biology as an overview of current knowledge.

Автор: John F. Atkins and Raymond F. Gesteland
Название: RNA Worlds: From Life`s Origins to Diversity in Gene Regulation
ISBN: 0879699469 ISBN-13(EAN): 9780879699468
Издательство: NBN International
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Цена: 142210.00 T
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Описание: Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA (ribonucleic acid) is now known to be a highly versatile molecule that has multiple roles in cells. It can function as an enzyme, scaffold various subcellular structures,
and regulate gene expression through a variety of mechanisms, as well as act as a key component of the protein synthesis and splicing machinery. Perhaps most interestingly, increasing evidence indicates that RNA preceded DNA as the hereditary material and played a crucial role in the early evolution
of life on Earth. This volume reviews our understanding of two RNA worlds: the primordial RNA world before DNA, in which RNA was both information store and biocatalyst; and the contemporary RNA world, in which mRNA, tRNA, rRNA, siRNA, miRNA, and a host of other RNAs operate. The early chapters of
the book analyze the role of RNA in the first life forms and the appearance of cells. Subsequent chapters examine riboswitches and ribozymes, establishing what the RNA molecule is capable of alone. The book goes on to discuss the evolution of ribosomes and the functions of RNPs, before reviewing the
recent work that has revolutionized our understanding of gene regulation by non-coding RNAs, including miRNAs and siRNAs. Also covered are viral RNAs, telomerase RNA, and tools for scientists who work on RNA. The book is thus essential reading for all molecular biologists and biochemists, as well as
chemists interested in RNA technology, information storage, or enzyme catalysis.