Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Автор: Fleming, Diane O. Название: Biological safety ISBN: 1555816207 ISBN-13(EAN): 9781555816209 Издательство: Wiley Рейтинг: Цена: 126670.00 T Наличие на складе: Поставка под заказ. Описание:
Good science is safe science
Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk--no matter how small--must be considered, assessed, and properly mitigated. If the science is not safe, it is not good science. Now in its fifth edition, Biological Safety: Principles and Practices remains the most comprehensive biosafety reference.
This book presents the guiding principles of laboratory safety, including the identification, assessment, and control of the broad variety of risks encountered in laboratories, production facilities, classrooms, and other unique environments. Specifically, Biological Safety covers
protection and control elements, ranging from biological safety cabinets and personal protection systems to workplace practices and decontamination methods
administrative controls in biorisk management, including regulations, guidelines, and compliance
various aspects of risk assessment, including bacterial, viral, mycotic, zoonotic, and molecular agents; protozoa and helminthes; viral vectors, allergens, and toxins; and decontamination, aerobiology, occupational medicine, and training topics
A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological Safety is also a critical reference for laboratory managers and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.
Автор: Li, Cheng Wei Название: Big Mechanisms in Systems Biology ISBN: 0128094796 ISBN-13(EAN): 9780128094792 Издательство: Elsevier Science Рейтинг: Цена: 116780.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource.
This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements.
The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research.
This book focuses on the biological mechanisms of minimal residual disease (MRD) and recurrence. It integrates this biology in solid cancers and in hematological malignancies. It reports also on technological advancements for monitoring MRD, derived from mechanistic insights. Chapters in solid and hematological malignancies address stem cell biology, genetics, epigenetics and micro-environmental regulation of dormant MRD. Novel insight into technologies for molecular phenotyping of MRD and monitoring of CTCs, DTCs and cell free RNA and DNA are also addressed extensively. Five chapters explore the above concepts in solid cancers such as prostate, breast, melanoma, head and neck and esophageal. Two chapters also explore the basic mechanisms of vascular biology targeting and epigenetic mechanisms regulating pluripotency programs during dormancy. Similar biology is explored in hematological malignancies such as T-ALL, CML, AML and multiple myeloma in additional four chapters. This book is edited and prefaced by Dr. Julio Aguirre-Ghiso, an expert in dormancy and recurrence. The chapters are written by world-recognized experts Drs. Ravi Bahtia, Samir Parekh, Russel Taichman, Monica Guzman, David Hoon, Denis Schewe, Irmela Jeremias, Cyrus Ghajar, Maria Soledad Sosa and Nicholas Stoecklein. The topic of this book is of particular interest to both basic cancer cell biologists and physician scientists that are working to provide a more integrated view of the biology of MRD and to those interested in working on or learning about this paradigm. The integrated and cross-disciplinary focus of the book from biology to medicine seeks to help bridge gaps to improve cancer care and prevent recurrences.
Автор: Alberts Bruce Название: Molecular biology of the cell 6 ed ISBN: 0815344643 ISBN-13(EAN): 9780815344643 Издательство: Wiley Рейтинг: Цена: 112200.00 T Наличие на складе: Невозможна поставка. Описание: As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
Автор: Karimi Название: Molecular Mechanisms of Autonomy in Biological Systems ISBN: 3319918230 ISBN-13(EAN): 9783319918235 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems.
Автор: Craig Nancy Название: Molecular Biology Principles of Genome Function ISBN: 0199658579 ISBN-13(EAN): 9780199658572 Издательство: Oxford Academ Рейтинг: Цена: 61240.00 T Наличие на складе: Поставка под заказ. Описание: A fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated coverage of experimental methods and approaches, Molecular Biology is the perfect companion to any molecular biology course.
Автор: Alberts Bruce, Johnson Alexander, Lewis Julian Название: Molecular Biology of the Cell, 6 ed. ISBN: 0815344325 ISBN-13(EAN): 9780815344322 Издательство: Wiley Рейтинг: Цена: 0.00 T Наличие на складе: Невозможна поставка. Описание: The definitive text in cell biology.
Автор: Lodish H.; Berk A. et al Название: Molecular Cell Biology. 8 ed ISBN: 1464187444 ISBN-13(EAN): 9781464187445 Издательство: Springer Рейтинг: Цена: 74530.00 T Наличие на складе: Невозможна поставка. Описание: With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on key experiments, Molecular Cell Biology has justly earned an impeccable reputation as an exciting and authoritative textbook. Avoiding an encyclopedic approach, the book grounds its coverage in the experiments that define our understanding of cell biology, engaging students with the exciting breakthroughs that define the field’s history and point to its future. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. Molecular Cell Biology is available with LaunchPad. LaunchPad combines an interactive ebook with high-quality multimedia content and ready-made assessment options, including LearningCurve adaptive quizzing. See ‘Instructor Resources’ and ‘Student Resources’ for further information.
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