Targeting Trafficking in Drug Development, Alfredo Ulloa-Aguirre; Ya-Xiong Tao
Автор: Alfredo Ulloa-Aguirre; Ya-Xiong Tao Название: Targeting Trafficking in Drug Development ISBN: 3319741632 ISBN-13(EAN): 9783319741635 Издательство: Springer Рейтинг: Цена: 204040.00 T Наличие на складе: Поставка под заказ. Описание: Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.
Автор: Kerry B. Barker, Sandeep M. Menon, Ralph B. D`Agostino, Siyan Xu, Bo Jin Название: Biosimilar Clinical Development: Scientific Considerations and New Methodologies ISBN: 1482231697 ISBN-13(EAN): 9781482231694 Издательство: Taylor&Francis Рейтинг: Цена: 132710.00 T Наличие на складе: Нет в наличии. Описание: Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and analysis of pharmacokinetics (PK) studies, and the design and analysis of efficacy studies.
Автор: Steven Kanner Название: Tumor Metabolome Targeting and Drug Development ISBN: 146149544X ISBN-13(EAN): 9781461495444 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism.
Автор: Steven Kanner Название: Tumor Metabolome Targeting and Drug Development ISBN: 1493953435 ISBN-13(EAN): 9781493953431 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism.
This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices.
This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.
Автор: Jose das Neves Название: Drug Delivery and Development of Anti-HIV Microbicides ISBN: 9814463566 ISBN-13(EAN): 9789814463560 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Невозможна поставка. Описание:
The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issues related to the subject are discussed. In the absence of a cure, prophylaxis represents a cornerstone in the battle against infection. One promising strategy comprises the use around the time of sexual intercourse of vaginal/rectal products containing antiviral compounds, termed microbicides. It is now recognized that specific development of drug dosage forms and/or drug delivery systems is an indispensable aspect for the success of microbicides. Different groups strived over the last decade to optimize the biophysical and technological performance of traditional dosage forms (gels, tablets, and suppositories) to fulfill the specificities of microbicides use, without neglecting users' preferences and affordability issues. Moreover, new formulation approaches, such as vaginal rings and films, nanotechnology-based systems, stimuli-sensitive formulations, targeted drug delivery systems, among others have been proposed and are currently undergoing pre-clinical or even clinical testing.
Автор: Held, Jr Название: Deep Homology? ISBN: 1316601218 ISBN-13(EAN): 9781316601211 Издательство: Cambridge Academ Рейтинг: Цена: 40120.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a comparison of the genetic circuits of Homo sapiens and Drosophila melanogaster to reveal the evidence for deep homology, from the field of evolutionary developmental biology. Individual body parts including the nervous system, limbs and heart are compared in chapters that also feature concept maps and encyclopaedic tables to aid learning.
Автор: Jolles Название: New Approaches to Drug Development ISBN: 3764361298 ISBN-13(EAN): 9783764361297 Издательство: Birkhauser Verlag AG Рейтинг: Цена: 289670.00 T Наличие на складе: Нет в наличии. Описание: This work reviews discoveries in drug research and highlights some of the many therapeutic possibilities whose growing applications can only be estimated in part. Contributors to the text work in the fields of genetics and molecular biology, pharmacology, genetic engineering and psychiatry.
Автор: Teicher Название: Anticancer Drug Development Guide. 2ed.2004 ISBN: 1588292282 ISBN-13(EAN): 9781588292285 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This thoroughly updated and expanded second edition of Beverly Teicher's widely used classic survey provides a step-by-step guide to anticancer drug development from initial design through FDA approval. The authors have included new material on the use of high throughput screening in industry, on specialized in vitro/in vivo procedures employed by the National Cancer Institute (NCI) in preclinical drug evaluations, and on nonclinical testing to support both human clinical trials, as well as trials of biologic oncology products. The chapters on phase I, II, and III clinical trials and on novel phase II clinical trial designs for targeted therapies have been significantly updated, along with those on cancer drug development in Europe, working with the NCI, and the FDA's role in cancer drug development and setting requirements for approval.
Автор: Krishna, Rajesh Название: Biopharmaceutics applications in drug development ISBN: 1441944346 ISBN-13(EAN): 9781441944344 Издательство: Springer Рейтинг: Цена: 204040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.
Автор: Wang Название: Predictive ADMET: Integrated Approaches in Drug Discovery and Development ISBN: 1118299922 ISBN-13(EAN): 9781118299920 Издательство: Wiley Рейтинг: Цена: 142510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: By guiding in the application of techniques and tools for predicting ADMET outcomes in drug candidates, Predictive ADMET offers a road map for drug discovery scientists to generate effective and safe drugs for unmet medical needs.
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