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The Genetics and Development of Scoliosis, Kenro Kusumi; Sally L. Dunwoodie


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Цена: 93160.00T
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Автор: Kenro Kusumi; Sally L. Dunwoodie
Название:  The Genetics and Development of Scoliosis
ISBN: 9783030079444
Издательство: Springer
Классификация:




ISBN-10: 3030079449
Обложка/Формат: Soft cover
Страницы: 199
Вес: 0.33 кг.
Дата издания: 2018
Язык: English
Издание: Softcover reprint of
Иллюстрации: 12 illustrations, color; 17 illustrations, black and white; xii, 199 p. 29 illus., 12 illus. in color.
Размер: 234 x 156 x 11
Читательская аудитория: General (us: trade)
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.

Дополнительное описание: Chapter1: Developmental and Functional Anatomy of the Spine.- Chapter2: Environmental Factors and Axial Skeletal Dysmorphogenesis.- Chapter3: Congenital Scoliosis and Segmentation Defects of the Vertebrae in the Genetic Clinic.- Chapter4: The Genetics Con


Early Onset Scoliosis

Автор: El-Hawary, Ron, Eberson, Craig P.
Название: Early Onset Scoliosis
ISBN: 3319715798 ISBN-13(EAN): 9783319715797
Издательство: Springer
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Цена: 121110.00 T
Наличие на складе: Поставка под заказ.
Описание: Comprised exclusively of clinical cases demonstrating the management of idiopathic, congenital, syndromic and neuromuscular early onset scoliosis (EOS), this concise, practical casebook will provide orthopedic surgeons with the best real-world strategies to properly manage the differing presentations of EOS they may encounter. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome, clinical pearls and pitfalls, and literature review. Cases included illustrate different types and management strategies for EOS, including various spine-based growing rods, the vertical expandable prosthetic titanium rib (VEPTR), anterior vertebral body tethering (AVBT) and congenital resection. Treatment strategies for EOS with related conditions such as myelomeningocele, cerebral palsy and skeletal dysplasia are also discussed, as are common complications and the role of traction.Pragmatic and reader-friendly, Early Onset Scoliosis: A Clinical Casebook is an excellent resource for pediatric orthopedic surgeons and other physicians confronted with both common and complex disorders of the child’s spine.

The Genetics and Development of Scoliosis

Автор: Kusumi
Название: The Genetics and Development of Scoliosis
ISBN: 3319901486 ISBN-13(EAN): 9783319901480
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent genetic studies of the spine has enhanced the understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. These findings are discussed in this timely review of scoliosis and developmental studies of the spine.

The Genetics and Development of Scoliosis

Автор: Kenro Kusumi; Sally L. Dunwoodie
Название: The Genetics and Development of Scoliosis
ISBN: 1489982965 ISBN-13(EAN): 9781489982964
Издательство: Springer
Рейтинг:
Цена: 174130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent genetic studies of the spine has enhanced the understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. These findings are discussed in this timely review of scoliosis and developmental studies of the spine.

Three-Dimensional Treatment for Scoliosis

Автор: Lehnert-Schroth, Christa
Название: Three-Dimensional Treatment for Scoliosis
ISBN: 0914959026 ISBN-13(EAN): 9780914959021
Издательство: Неизвестно
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Цена: 55130.00 T
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Описание: Causation is asymmetrical in many different ways. Causes precede effects; explanations cite causes not effects. Agents use causes to manipulate their effects; they don`t use effects to manipulate their causes. Effects of a common cause are correlated; causes of a common effect are not. This is a major book for philosophers of science that will also prove insightful to economists and statisticians.

Pathogenesis of Idiopathic Scoliosis

Автор: Masafumi Machida; Stuart L. Weinstein; Jean Dubous
Название: Pathogenesis of Idiopathic Scoliosis
ISBN: 4431568611 ISBN-13(EAN): 9784431568612
Издательство: Springer
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Цена: 125770.00 T
Наличие на складе: Невозможна поставка.
Описание: Research into what causes IS has focused on the structural elements of the spine, spinal musculature, collagenous structures, the endocrine system, the central nervous system, and genetics.

Adult Lumbar Scoliosis

Автор: Eric O. Klineberg
Название: Adult Lumbar Scoliosis
ISBN: 3319838032 ISBN-13(EAN): 9783319838038
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Невозможна поставка.
Описание: Providing a sound definition and review of the pertinent treatment goals for the management of adult lumbar scoliosis, this practical and comprehensive guide covers everything from pre-operative evaluation and radiography to post-operative management and complications.

Idiopathic Scoliosis. The Harms Study Group Treatment Guide

Автор: Peter O. Newton
Название: Idiopathic Scoliosis. The Harms Study Group Treatment Guide
ISBN: 1604060247 ISBN-13(EAN): 9781604060249
Издательство: Thieme Verlagsgruppe
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Цена: 225710.00 T
Наличие на складе: Невозможна поставка.
Описание:

Based on over a decade of research and observation conducted by the members of the Harms Study Group and other spinal deformity experts from around the world, this must-have clinical reference provides focused coverage of the most current evaluation and treatment guidelines for idiopathic scoliosis. It draws on case studies to guide readers through specific surgical and nonoperative approaches to the multiple types of adolescent idiopathic spinal deformity, including practical information on the rationale for each approach, techniques, and results.

Features:

  • In-depth information culled from vast clinical data of world-renowned experts in the Harms Study Group
  • Curve assessment and treatment recommendations listed by curve type and pattern
  • Comprehensive discussion of pathogenesis and epidemiology, osteobiologics for spinal fusion, anesthesia for scoliosis surgery, surgical complications, and more
  • Chapters on key treatment decisions, such as the selection of fusion levels, that teach readers how to critically address clinical questions
  • More than 600 high-quality illustrations, including numerous full-color clinical photographs, detailed line drawings, and complementary high-resolution radiographs

This state-of-the-art text is ideal for orthopaedic surgeons, neurosurgeons, and spine fellows, and is an invaluable companion for any practitioner involved in the surgical and nonsurgical care of patients with spinal deformity.


Scoliosis: Diagnosis, Classification and Management Options

Автор: Federico Canavese, Antonio Andreacchio, Hongwen Xu
Название: Scoliosis: Diagnosis, Classification and Management Options
ISBN: 1536144649 ISBN-13(EAN): 9781536144642
Издательство: Nova Science
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Цена: 257650.00 T
Наличие на складе: Невозможна поставка.
Описание: The importance of the initial diagnosis and subsequent management of scoliosis is crucial as it affects the patients future. Initial diagnosis is highly important in orientating the patient and correlating available therapeutic means to the expected results. Since the 1900s, the surgical approach to scoliosis has changed as thoughts and possibilities have evolved. Nowadays, progressive spinal deformities can be managed with specific orthopedic devices or vertebral arthrodesis surgery, depending on the age of the patient. Additionally, the type and extent of scoliotic deformity as well as on the presence of comorbidities have aided in the transforming of these methods. Arthrodesis is not considered the best treatment for younger patients; however, it becomes almost inevitable to cure important deformities of the spine in older children. Surgical fusion in patients with severe scoliosis can improve the deformity, but the spine is rendered more rigid and spinal growth is subsequently affected. The information contained in this clinical book are derived from the valuable experience of over 40 authors and co-authors from all over the world, and we hope this format will help the reader at the critical junctures to which decisions must be made. All the participants provided their own analysis, and their therapeutic choices and contributions have served this project well. This book would not exist without their efforts, diligence and commitment. This clinical book is an opportunity for every physician and surgeon dealing with children and adolescents with scoliosis to obtain updates concerning actual trends and knowledge in this field of study.

Bioinformatics and Computational Biology in Drug Discovery and Development

Автор: Loging
Название: Bioinformatics and Computational Biology in Drug Discovery and Development
ISBN: 0521768004 ISBN-13(EAN): 9780521768009
Издательство: Cambridge Academ
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Цена: 61240.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Providing a comprehensive overview of the drug discovery and development pipeline, this book focuses on the integral role that computational biology methods play in this process. Covering technological advances and their relation to drug developmental processes, readers are exposed to new methods of discovery utilising the available technology.

Post-genomic Approaches in Drug and Vaccine Development

Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra
Название: Post-genomic Approaches in Drug and Vaccine Development
ISBN: 8793102844 ISBN-13(EAN): 9788793102842
Издательство: Taylor&Francis
Рейтинг:
Цена: 88800.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, genome sequencing projects and associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, and understand their role in physiological pathways and associated diseases with the aim of translating these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic, and metabolomic approaches. Post-genomic Approaches to Drug and Vaccine Development focuses on some key advances in the field.

Technical topics discussed in the book include:
- Drug discovery
- Target identification and prioritization
- Hypothesis driven multi-target drug design
- Genomics in vaccine development
- Gene regulatory networks
- Vaccine design and development
- Prediction of drug side effects in silico

Genetics and Global Public Health: Sickle Cell and Thalassaemia

Автор: Simon M. Dyson, Karl Atkin
Название: Genetics and Global Public Health: Sickle Cell and Thalassaemia
ISBN: 113811118X ISBN-13(EAN): 9781138111189
Издательство: Taylor&Francis
Рейтинг:
Цена: 51030.00 T
Наличие на складе: Невозможна поставка.
Описание: Sickle cell and thalassaemia are the world`s leading genetic conditions. This book breaks new ground in bringing together social scientific research on the experiences of peoples living with a haemoglobin disorder. This book was originally published as a special issue of Ethnicity and Health.


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