How to Design and Implement Powder-to-Tablet Continuous Manufacturing Systems provides a comprehensive overview on the considerations necessary for the design of continuous pharmaceutical manufacturing processes. The book covers both the theory and design of continuous processing of associated unit operations, along with their characterization and control. In addition, it discusses practical insights and strategies that the editor and chapter authors have learned. Chapters cover Process Analytical Technology (PAT) tools and the application of PAT data to enable distributed process control.
With numerous case studies throughout, this valuable guide is ideal for those engaged in, or learning about, continuous processing in pharmaceutical manufacturing.
Discusses the development of strategy blueprints in the design of continuous processes
Shows how to create process flowsheet models from individual unit operation models
Includes a chapter on characterization methods for materials, the use of statistical methods to analyze material property data, and the use of material databases
Covers the evolving regulatory expectations for continuous manufacturing
Provides readers with ways to more effectively navigate these expectations
Автор: Watson, David G. Название: Pharmaceutical Analysis: A Textbook for Pharmacy Students and Pharmaceutical Chemists 4E IE ISBN: 0702070297 ISBN-13(EAN): 9780702070297 Издательство: Elsevier Science Рейтинг: Цена: 22690.00 T Наличие на складе: Есть Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over GBP10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition.
Автор: Shah B. Название: Textbook Of Pharmacognosy And Phytochemistry 2Ed ISBN: 9386217732 ISBN-13(EAN): 9789386217738 Издательство: CBS India Рейтинг: Цена: 36580.00 T Наличие на складе: Есть
The phenomenon of adhesion is of cardinal importance in the pharmaceutical, biomedical and dental fields. A few eclectic examples will suffice to underscore the importance/relevance of adhesion in these three areas. For example, the adhesion between powdered solids is of crucial importance in tablet manufacture. The interaction between biodevices (e.g., stents, bio-implants) and body environment dictates the performance of such devices, and there is burgeoning research activity in modifying the surfaces of such implements to render them compatible with bodily components. In the field of dentistry, the modern trend is to shift from retaining of restorative materials by mechanical interlocking to adhesive bonding.
This unique book addresses all these three areas in an easily accessible single source. The book contains 15 chapters written by leading experts and is divided into four parts: General Topics; Adhesion in Pharmaceutical Field; Adhesion in Biomedical Field; and Adhesion in Dental Field. The topics covered include:
- Theories or mechanisms of adhesion. - Wettability of powders. - Role of surface free energy in tablet strength and powder flow behavior. - Mucoadhesive polymers for drug delivery systems. - Transdermal patches. - Skin adhesion in long-wear cosmetics. - Factors affecting microbial adhesion. - Biofouling and ways to mitigate it. - Adhesion of coatings on surgical tools and bio-implants. - Adhesion in fabrication of microarrays in clinical diagnostics. - Antibacterial polymers for dental adhesives and composites. - Evolution of dental adhesives. - Testing of dental adhesives joints.
Автор: Teerapol Srichana Название: Dry Powder Inhalers: Formulation, Device & Characterization ISBN: 1536106410 ISBN-13(EAN): 9781536106411 Издательство: Nova Science Рейтинг: Цена: 83410.00 T Наличие на складе: Невозможна поставка. Описание: This book is a compilation of most works published during 2000-2016 in the area of dry powder inhalers, especially related to the issues with formulation and device design. The dry powder inhalers aim to deliver the medication to the respiratory airways. It is suitable for postgraduate students and researchers who work in the areas of dry powder inhalers. It provides some background knowledge in size characterization, flow properties, forces, and interaction of air and particles. It also ends with in vitro quality control of dry powder inhalers. This book was finished in Hawaii where the author spent his time during April 2016. Thank you to Prince of Songkla University for the financial support. The author had to work very hard for one month without a holiday. Thank you to Professor Aran Pattanothai for overseeing this work to make sure that the researchers were on schedule all the time. Thanks to the authors staff at the Graduate School, Prince of Songkla University who had to work hard and be patient when the author was not in the office. Thanks to the authors wife and son who had to wait for him at home in Thailand. Thanks to Dr Tan Suwandecha and Dr Janwit Dechraksa for their great efforts in copy editing and compiling all the references. The author also thanks Dr Somchai Sawatdee and Dr Dhamodharan Bakkiyaraj for their comments, and Dr Padmavathi Alwar Ramanujam for her proofreading. The greatest help was from Professor Alan Coombes, Professor Pornanong Aramwit, and Dr Brian Hodgeson for their criticisms and comments to make this book readable.
Автор: Hickey Название: Pharmaceutical Powder and Particles ISBN: 3319912194 ISBN-13(EAN): 9783319912196 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Поставка под заказ. Описание: This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.
Название: Pharmaceutical Chemistry ISBN: 0199655308 ISBN-13(EAN): 9780199655304 Издательство: Oxford Academ Рейтинг: Цена: 35890.00 T Наличие на складе: Поставка под заказ. Описание: Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, an understanding of organic compounds and their reactions is essential.
Автор: Razdan B. Название: Medicinal Chemistry 2Ed (Pb 2019) ISBN: 9387964051 ISBN-13(EAN): 9789387964051 Издательство: CBS India Рейтинг: Цена: 45290.00 T Наличие на складе: Невозможна поставка. Описание: This is the thoroughly revised, rewritten and enlarged second edition of a core textbook for undergraduate students of pharmacy, as well as other related disciplines that offer medicinal chemistry as an elective. Each of the 38 chapters provide an introduction, classes of compounds used, their mechanism of action, and structure-activity relationships. At the end of each chapter, a synthesis of selected compounds used in clinical practice is given. The latest developments in the field of medicinal chemistry, along with three new chapters, have been added to this upddated edition. All the illustrations, chemical configurations and molecular modeling have been modified, improved and redrawn to clarify the content.
Автор: S. Narasimha Murthy Название: Dermatokinetics of Therapeutic Agents ISBN: 1138114588 ISBN-13(EAN): 9781138114586 Издательство: Taylor&Francis Рейтинг: Цена: 81650.00 T Наличие на складе: Невозможна поставка. Описание:
Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.
Presenting the first comprehensive reference on this important area of research, Dermatokinetics of Therapeutic Agents includes a general overview of the theoretical as well as practical aspects of dermatokinetics and addresses the impact of a drug delivery system on the dermatokinetics of drugs. Chapters and illustrations cover introductory aspects and the significance, methods, and models used in dermatokinetic studies of therapeutic agents.
Topics include:
Theoretical Models for Dermatokinetics of Therapeutic Agents
Drug Delivery Approaches to Modulate Dermatokinetics of Drugs
Conventional Methods of Cutaneous Drug Sampling
Cutaneous Microdialysis
Sampling Substrates by Skin Permeabilization
Spectroscopic Techniques in Dermatokinetics Studies
Regulatory Perspective of Dermatokinetic Studies
Автор: Denyer Stephen P Название: Hugo and russell`s pharmaceutical microbiology ISBN: 1444330632 ISBN-13(EAN): 9781444330632 Издательство: Wiley Рейтинг: Цена: 65420.00 T Наличие на складе: Поставка под заказ. Описание: THE TWENTY ETUDES FOR PIANO were composed during the years from 1991 to 2012. Their final configuration into Book 1 and Book 2 was determined by the music itself in the course of its composition.
Book 1 (Etudes 1-10) had a twin objective - to explore a variety of tempi, textures and piano techniques. At the same time it was meant to serve as a pedagogical tool by which I would improve my piano playing. In these two ways, Book 1 succeeded very well. I learned a great deal about the piano and in the course of learning the music, I became a better player.
New projects came along and interrupted the work on the Etudes for several years. Perhaps for that reason, when I took up work with the Etudes again I found the music was following a new path. Though I had settled questions of piano technique for myself in Book 1, the music in Book 2 quickly began to suggest a series of new adventures in harmony and structure.
In this way, Books 1 and 2, taken together, suggest a real trajectory that includes a broad range of music and technical ideas.
In the end, the Etudes are meant to be appreciated not only by the general listener, but especially by those who have the ability and patience to learn, play and perform the music themselves.
Автор: McCormick, Kate Jr, D. Wylie McVay Название: Pharmaceutical Process Design and Management ISBN: 1138255505 ISBN-13(EAN): 9781138255500 Издательство: Taylor&Francis Рейтинг: Цена: 53070.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A quality product or service is the successful and profitable outcome of organising resources, as judged by the final customer. Every business unit needs processes in order to do this effectively; and all processes must be documented so that achievements can be measured and future improvements planned and implemented. Pharmaceutical Process Design and Management takes a step-wise approach to process management. It presents the various elements comprising a process (man, machine, materials, method and environment); it looks at quality control and quality assurance, tools for quality improvements and ways of structuring a process into discrete, fully accountable elements; it proposes that for processes to run successfully, all operators must be the initial problem-solvers; finally, it illustrates how, with the right tools, every problem can be broken down into solvable elements. Learn how to deploy a science and risk-based approach to pharmaceutical manufacturing, by taking a fundamental approach to process design and management and, as a consequence, keep your customers satisfied and your profits healthy.
Автор: Demetzos, Costas Название: Pharmaceutical Nanotechnology: Fundamentals and Practical Applications ISBN: 981100790X ISBN-13(EAN): 9789811007903 Издательство: Springer Рейтинг: Цена: 65210.00 T Наличие на складе: Невозможна поставка. Описание: This textbook explains the fundamental aspects of nanotechnology and fills the gap between bio-inspired nanotechnological systems and functionality of living organisms, introducing new insights to their physicochemical, biophysical and thermodynamic behaviour. Addressed to all those involved in recent advances in pharmaceutics, this book is divided in three major parts: Part A refers to the physicochemical and thermodynamics aspects of nanosystems, wherein their biophysical behaviour is correlated with that of the cells of living organisms; Part B refers to the application of nanotechnology in imaging, diagnostics and therapeutics; Part C is focused on issues regarding safety and nanotoxicity of nanosystems, and the regulatory framework that surrounds these. The text promotes the concept that biophysics, thermodynamics and nanotechnology are considered to be emerging tools that, when approached within regulatory boundaries, provide new and integrated knowledge for the production of new medicines. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.
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