Handbook of Nutrition, Diet, and Epigenetics, Vinood B. Patel; Victor R. Preedy
Автор: Johannes Backs, Timothy McKinsey Название: Epigenetics in Cardiac Disease ISBN: 3319414550 ISBN-13(EAN): 9783319414553 Издательство: Springer Рейтинг: Цена: 97820.00 T Наличие на складе: Есть Описание: This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field. Edited and written by internationally respected experts, it addresses the needs of professors, students and researchers working in the fields of cardiac biology and epigenetics.
Автор: Patel Название: Handbook of Nutrition, Diet, and Epigenetics ISBN: 3319555294 ISBN-13(EAN): 9783319555294 Издательство: Springer Рейтинг: Цена: 492870.00 T Наличие на складе: Поставка под заказ. Описание: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.
Название: Nutrition and Epigenetics ISBN: 1482203812 ISBN-13(EAN): 9781482203813 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. Each chapter gives a unique perspective on a different nutritional or dietary component or group of components, and reveals novel mechanisms by which dietary factors modulate the epigenome and affect development processes, chronic disease, and the aging process. This pivotal text:
Documents the epigenetic effect of antioxidants and their health benefits
Adds to the understanding of mechanisms leading to disease susceptibility and healthy aging
Illustrates that the epigenetic origins of disease occur in early (fetal) development
Synthesizes the data regarding nutrient and epigenomic interactions
Nutrition and Epigenetics highlights the interactions among nutrients, epigenetics, and health, providing an essential resource for scientists and clinical researchers interested in nutrition, aging, and metabolic diseases.
Автор: Burdge Graham, Lillycrop Karen Название: Nutrition, Epigenetics and Health ISBN: 9813143304 ISBN-13(EAN): 9789813143302 Издательство: World Scientific Publishing Цена: 91870.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.
Автор: Walter Doerfler; Petra B?hm Название: Epigenetics - A Different Way of Looking at Genetics ISBN: 3319271849 ISBN-13(EAN): 9783319271842 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents epigenetics research as a new way of looking at genetics. Topics range from basic epigenetics mechanisms to development of cells and organisms and the biological basis of diseases. In addition the book focuses on immunology and the role of viruses in epigenetics.
Автор: Charles Spillane; Peter C. McKeown Название: Plant Epigenetics and Epigenomics ISBN: 1627037721 ISBN-13(EAN): 9781627037723 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants.
Автор: Tollefsbol, Trygve Название: The Epigenetics of Autoimmunity ISBN: 0128099127 ISBN-13(EAN): 9780128099124 Издательство: Elsevier Science Рейтинг: Цена: 159450.00 T Наличие на складе: Поставка под заказ. Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.
Автор: Trygve Tollefsbol Название: Medical Epigenetics ISBN: 0128032391 ISBN-13(EAN): 9780128032398 Издательство: Elsevier Science Рейтинг: Цена: 151310.00 T Наличие на складе: Поставка под заказ. Описание: "
Medical Epigenetics" is an inclusive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic disease that affect these systems, and modes of treating epigenetic-based disorders and diseases. This book provides stand-alone coverage of all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. It is useful not only to physicians, nurses, medical students, and many others directly involved with healthcare, but also investigators in life sciences, biotech companies, graduate students, and all others who are interested in more applied aspects of epigenetics.
The expansion of the field of epigenetics has brought a wealth of information with respect to variations in phenotypes that are heritable. In addition, many advances have emerged that have shown epigenetic aberrations as central to a number of diseases and disorders that were previously thought to be manifested primarily through genetic factors. Along with the remarkable studies that have been made in our understanding of epigenetic-based diseases and disorders has come new information that allows treatments that target these many epigenetic aberrations. "Medical Epigenetics" brings all of this knowledge together to comprehensively review the state of medical epigenetics in one defining volume.
The basic design of "Medical Epigenetics" is to lead the reader from the fundamental mechanisms of epigenetics as they apply to humans through approaches for treating epigenetic-based diseases. This book begins with the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics. "Medical Epigenetics" closes with a chapter on future prospects in medical epigenetics. This book is by far the most complete book in the area of applied epigenetics. Focuses on practical and applied aspects of medical epigeneticsIncludes peer-reviewed chapters with up-to-date coverage of emerging topics in medical epigenetics by leading expertsAppeals to those interested in fundamental epigenetics and inheritance, as well as those with more clinical interests including practicing physicians and other health care professionalsCovers the basic tenets of epigenetics in human systems and progresses through general medical aspects of epigenetics, epigenetics or system disorders, multi-system medical epigenetics, pharmacology of epigenetics, and therapeutic epigenetics
Автор: Trygve Tollefsbol Название: Handbook of Epigenetics, ISBN: 0123757096 ISBN-13(EAN): 9780123757098 Издательство: Elsevier Science Рейтинг: Цена: 128710.00 T Наличие на складе: Поставка под заказ. Описание:
Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and imprinting diseases are on the horizon.
This comprehensive collection of reviews written by leaders in the field of epigenetics provides a broad view of this important and evolving topic. From molecular mechanisms and epigenetic technology to discoveries in human disease and clinical epigenetics, the nature and applications of the science will be presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders.
Contributions by leading international investigators involved in molecular research and clinical and therapeutic applications
Integrates methods and biological topics with basic and clinical discoveries
Includes coverage of new topics in epigenetics such as prions, regulation of long-term memory by epigenetics, metabolic aspects of epigenetics, and epigenetics of neuronal disorders
Автор: L. Joseph Su; Tung-chin Chiang Название: Environmental Epigenetics ISBN: 1447166779 ISBN-13(EAN): 9781447166771 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: What is Epigenetics.- Epidemiology of environment and health.- Technologies in measuring epigenetics.- Epigenetic changes in hormone related disease.- Epigenetic effects of environmental chemicals bisphenol a and phthalates.- Environmental epigenetics: a role in endocrine diseases?.- Pregnancy exposures determine risk of breast cancer in multiple generations of offspring.- Environmental epigenetics and obesity - evidences from animal to epidemiologic studies.- Environmental toxicants, epigenetics and cancer.- Aging, genes, environment and epigenetics.- Epigenetics: The link between nature and nurture.- Gene-Environment Interactions in Human Health.- Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.- Conclusions: Lessons from epigenetic research: the impact of environmental stress can be accumulated and resulted in diverse outcome.
Автор: Junjiang Fu, Saber Imani Название: Epigenetics in Cancer ISBN: 1783323590 ISBN-13(EAN): 9781783323593 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 98870.00 T Наличие на складе: Невозможна поставка. Описание: As the second leading cause of death, cancer has cast an overwhelming shadow on millions of lives worldwide. Everyone is affected in some way, if not by having the disease themselves, then by witnessing it in friends or loved ones.
Автор: Tollefsbol, Trygve Название: Tollefsbol-Transgenerational Epigenetics, 2e ISBN: 0128163631 ISBN-13(EAN): 9780128163634 Издательство: Elsevier Science Рейтинг: Цена: 176290.00 T Наличие на складе: Невозможна поставка. Описание:
Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born.
This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.
Presents a fully-updated and expanded release addressing transgenerational epigenetics, epigenetic mechanisms of gene regulation, and the role of epigenetics in human longevity and cancer
Examines the field from "bench-to-bedside," discussing basic science, disease management, current debates, and next steps in epigenetic research and drug discovery
Features chapter contributions from international experts
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