Diabetes and Aging-related Complications, Sho-ichi Yamagishi

Автор: Enzo Bonora; Ralph A. DeFronzo
Название: Diabetes Complications, Comorbidities and Related Disorders (EPZ)
ISBN: 3319444336 ISBN-13(EAN): 9783319444338
Издательство: Springer
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Цена: 260870.00 T
Наличие на складе: Невозможна поставка.
Описание: This book provides the reader with comprehensive information on the interactions between diabetes and a wide range of comorbid conditions and on disease management in such patients. It has the aim of empowering health care providers in their daily battle against the disease and its consequences. Diabetes has been identified by WHO and the United Nations as a medical emergency because of the increase in its global prevalence, which may reach one billion in three to four decades if the trend remains unchanged. Despite improved care that is helping to prolong life, diabetes impacts substantially on the quality of life of those affected and kills or disables several million people each year. The disease is systemic because all organs, tissues, and cells suffer in the presence of hyperglycemia and are damaged by the diabetic milieu. Unfortunately, most patients with diabetes will consequently experience chronic diabetic complications. This book will be of value for all physicians and nurses who care for patients with diabetes and face the challenge of treating hyperglycemia and related acute and chronic complications.

Автор: Slavin Rex, Wise Windy, Cohn Roy Marcus
Название: Encyclopedia of Diabetes: Volume 10 (Complications in Type 1 Diabetes)
ISBN: 1632411520 ISBN-13(EAN): 9781632411525
Издательство: Неизвестно
Цена: 153210.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book contains reviews regarding the pathogenesis of Type-1 Diabetes, which is a classic autoimmune disease. Genetic factors are responsible but they cannot describe the rapid, even overwhelming extent of this disease. It is important to comprehend eti

Автор: Florez Jose C.
Название: The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation
ISBN: 3319791281 ISBN-13(EAN): 9783319791289
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents the state of the art of type 2 diabetes genetics, from the process of genetic discovery to its interpretation and clinical application, and illustrates a model for other complex human phenotypes. The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further section goes beyond genetics to illustrate how other data sources can help interpret genetic data, such as leveraging population diversity, the correlation of genetic associations with physiological measurements, gene expression modulation, environmental factors and our microbial commensals. The third section describes advances in elucidating the complex path from association to function using in-depth sequencing and functional studies of the cellular and molecular effects of genes in the loci identified by genetics. The final section links our current understanding with clinically relevant questions, such as prediction, interactions with drugs or nutrients, and disease prevention, and paints a realistic but hopeful vision of the future.

Автор: Harold Rifkin; Margo P. Cohen
Название: The Polyol Paradigm and Complications of Diabetes
ISBN: 1461291089 ISBN-13(EAN): 9781461291084
Издательство: Springer
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Цена: 97820.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the last decade, it has become increasingly evident that the clini- cal and morphologic changes underlying many of the complications of diabetes, including cataract formation, retinopathy, nephropathy, neuropathy, and macrovascular disease, are preceded by a variety of disturbances of biochemical and physiologic origin. Dr. Cohen has recently written a superb monograph, entitled Diabetes and Protein Glycosylation: Measurement and Biologic Relevance, in which she thoroughly explores how enhanced nonenzymatic glycosylation in uncontrolled diabetes underscores the pressing need for main- tenance of long-term euglycemia. In the present volume, The Polyol Paradigm and Complications of Diabetes, she reviews, in a most succinct and thorough manner, how another biochemical mechan- ism, involving the polyol pathway, is involved in the pathogenesis of such diabetes complications as retinopathy, neuropathy, nephropa- thy, and cataract formation. Dr. Cohen gives us a clearly written and comprehensive mono- graph, reviewing the chemistry of the polyol pathway and of the aldose reductase inhibitors, and the pathophysiologic significance of increased polyol pathway activity in a variety of tissues affected by Vlll Foreword diabetes mellitus. She insightfully describes the relationship of increased polyol pathway activity to altered metabolism of inositol- containing phospholipids and to changes in various tissue concentra- tions of myo-inositol. Finally, she provides us with a careful review of the existing experimental and clinical studies with a variety of different aldose reductase inhibitors that have been and are being performed in the hope of preventing or reversing long-term compli- cations of diabetes.

Автор: Slavin Rex, Wise Windy, Cohn Roy Marcus
Название: Encyclopedia of Diabetes: Volume 12 (Pathophysiology and Complications of Type 2 Diabetes)
ISBN: 1632411547 ISBN-13(EAN): 9781632411549
Издательство: Неизвестно
Цена: 156590.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Type-2 Diabetes is now a severe health problem worldwide. Patients with this disease have 2-4 times greater risk of renal and cardiovascular complications, mortality and morbidity. This unique book includes topics like pathophysiology and complications. C

Автор: Zachary Pearce
Название: Type 1 Diabetes: Causes, Treatment & Potential Complications
ISBN: 1631170007 ISBN-13(EAN): 9781631170003
Издательство: Nova Science
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Цена: 103480.00 T
Наличие на складе: Невозможна поставка.
Описание: Type 1 diabetes is a chronic auto-immune disease. Type 1 diabetes was previously called insulin-dependent diabetes mellitus (IDDM) or juvenile-onset diabetes. Type 1 diabetes develops when the bodys immune system destroys pancreatic beta cells, the only cells in the body that make the hormone insulin that regulates blood glucose. To survive, people with type 1 diabetes must have insulin delivered by injection or a pump. Topics discussed in this compilation include genetic and epigenetic studies of type 1 diabetes; blood pressure and diabetes during pregnancy; comparison of diseases-specific quality of life, metabolic control and cardiorespiratory fitness in physically active and inactive youths with type 1 diabetes; stem cells for the treatment of patients with type 1 diabetes; and the causes and potential complications of type 1 diabetes.

Автор: Jose C. Florez
Название: The Genetics of Type 2 Diabetes and Related Traits
ISBN: 3319015737 ISBN-13(EAN): 9783319015736
Издательство: Springer
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Цена: 174150.00 T
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Описание: Covering the very latest advanced insights into type-2 diabetes arising from the rapid developments in human genetics, this volume covers all aspects of the topic, from genetic discovery to interpretation of genetic findings and clinical applications.

Автор: American Diabetes Association
Название: Therapy for diabetes mellitus and related disorders
ISBN: 1580403042 ISBN-13(EAN): 9781580403047
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 66000.00 T
Наличие на складе: Нет в наличии.
Описание: Provides a concise overview of the advances on diabetes therapy, including glycemic control, obesity and type 2 diabetes in children, the role of exercise, geriatric diabetes, type 2 diabetes prevention, diabetes in pregnancy, insulin pump therapy and oral medications.

Автор: Donnelly
Название: Vascular Complications of Diabetes.2005
ISBN: 1405127856 ISBN-13(EAN): 9781405127851
Издательство: Wiley
Рейтинг:
Цена: 41240.00 T
Наличие на складе: Поставка под заказ.
Описание: Provides an overview of the clinical features and evidence-based therapies for microvascular and macrovascular disease in diabetes Provides detailed reviews of diabetic neuropathy and retinpathy, with emphasis on diagnosis and treatment Provides a description of the biochemical pathways involved in hyperglycaemia-induced structural and functional vascular abnormalities, in particular PKC as a new therapeutic target for delaying and reversing important pathological changes in neural, retinal, renal and endothelial tissues.