Hypothalamic-Pituitary Diseases, Felipe F. Casanueva; Ezio Ghigo

Автор: Eliza B. Geer
Название: The Hypothalamic Pituitary Adrenal Axis in Health and Disease
ISBN: 3319459481 ISBN-13(EAN): 9783319459486
Издательство: Springer
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Цена: 149060.00 T
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Описание: Cushing?s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

Автор: Brooke Swearingen; Beverly M. K. Biller
Название: Diagnosis and Management of Pituitary Disorders
ISBN: 1617378461 ISBN-13(EAN): 9781617378461
Издательство: Springer
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Цена: 231990.00 T
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Описание: This text is a review of current management techniques for pituitary tumors, incorporating recent advances and discussions by experienced clinicians. The use of both endocrinologists and neurosurgeons as chapter authors allows differing perspectives to be incorporated.

Автор: Goede Simon, Leow Melvin Khee
Название: Thyroid Systems Engineering: A Primer in Mathematical Modeling of the Hypothalamus-Pituitary-Thyroid Axis
ISBN: 8793609590 ISBN-13(EAN): 9788793609594
Издательство: Taylor&Francis
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Цена: 93910.00 T
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Описание: In recent years, a considerable amount of effort has been devoted, both in industry and academia, towards the behavioral modeling, evaluation and prediction of the hypothalamus pituitary thyroid system.Thyroid Systems Engineering targets an optimal treatment of people suffering from thyroid hormone disorders. The content is motivated by in-depth observations of such patients whose rich data supported the theoretical framework arising from formal mathematical reasoning, guided by the nature of thyroid physiology. Leveraging on the insights emerging from the unique combination of an electrical engineer working with a clinical thyroidologist, and both being scientists skilled in mathematics, the authors introduce this new discipline and field of scientific investigation aptly designated as Thyroid Systems Engineering.Readers will discover that mathematics can indeed model the behavior of the hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling, each of the eighteen chapters gives the reader a notion of the application of relevant mathematics to pertinent issues encountered in mainstream thyroidology. Many cellular processes resemble the flux of variables and states in a complex multi-parameter space through time analogous to current flow in electrical networks. It is then logical to apply the principles and physical laws of electrodynamics, electrical network theory, control systems theory and signal theory to many of the biological phenomena encountered in endocrinology. Such an approach is used liberally throughout the book and successfully yields elegant solutions to a number of models presented within.This book can serve as a reference to mathematical modeling in other aspects of endocrine physiology, and as the starting point for a fundamental course in medical modeling. It will appeal to postgraduates in electrical engineering, academic physicians and biomedical researchers. Further, readers equipped with advanced calculus, electrical network theory, control theory and signal theory should be able to follow the mathematical expositions that describe thyrotropic control. They represent a new discipline based on mathematical modeling in physiology applicable to medical diagnostics, measurement and treatment to cooperate in the clinical team and realize an optimized treatment for patients.

Автор: Eliza B. Geer
Название: The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease
ISBN: 3319834053 ISBN-13(EAN): 9783319834054
Издательство: Springer
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Цена: 102480.00 T
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Описание: Cushing?s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

Автор: Melmed, Shlomo
Название: The Pituitary
ISBN: 0128041692 ISBN-13(EAN): 9780128041697
Издательство: Elsevier Science
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Цена: 176290.00 T
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Описание: The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. . The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

Автор: Margaret E. Wierman
Название: Diseases of the Pituitary
ISBN: 0896033643 ISBN-13(EAN): 9780896033641
Издательство: Springer
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Цена: 231990.00 T
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Описание: Contains nineteen review articles that provide an overview of the normal function of the pituitary and of the diagnosis and treatment of pituitary disorders. This title features topics that range from normal hypothalamic-pituitary interactions and the processes that disrupt them to advances in pituitary imaging.

Автор: Margaret E. Wierman
Название: Diseases of the Pituitary
ISBN: 1461284384 ISBN-13(EAN): 9781461284383
Издательство: Springer
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Цена: 204040.00 T
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Описание: Nineteen cutting-edge review articles by leading authorities provide a comprehensive overview of the normal function of the pituitary and of the diagnosis and treatment of pituitary disorders.

Автор: Nachtigall
Название: Pituitary Tumors
ISBN: 331990907X ISBN-13(EAN): 9783319909073
Издательство: Springer
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Цена: 65210.00 T
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Описание: Comprised of cases presenting diverse clinical scenarios involving pituitary tumors and related conditions, this concise, practical casebook provides clinical endocrinologists with the best real-world strategies to properly diagnose and treat the various presentations and symptoms they may encounter in daily practice. Discussing macroprolactinoma, non-functioning adenoma, TSH-secreting adenoma, Cushing’s disease and acromegaly, each chapter is a case that provides a unique clinical presentation of a patient’s symptoms and clinical findings, diagnostic work-up and the thought process involved in navigating the treatment options, as well as the supporting evidence. Cases included illustrate different types of tumors, related disorders and special situations and considerations, in addition to various management strategies, complications and outcomes, with helpful clinical pearls and pitfalls.Pragmatic and reader-friendly, Pituitary Tumors: A Clinical Casebook is written by experts in the field and is designed to facilitate and guide endocrinologists in the sometimes challenging decision-making process by presenting real case scenarios that span the spectrum of pituitary tumor presentations and treatment options.

Автор: Kohn
Название: Pituitary Disorders of Childhood
ISBN: 3030113388 ISBN-13(EAN): 9783030113384
Издательство: Springer
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Цена: 130430.00 T
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Описание: This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know.

Автор: Stanton Lee
Название: Pituitary Adenomas: A Study of Non Cancerous Tumors
ISBN: 1632413213 ISBN-13(EAN): 9781632413215
Издательство: Неизвестно
Цена: 85770.00 T
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Описание: Non-cancerous tumors which occur in the brain are called pituitary adenomas. This book is a wholesome account on the most known pathology of the pituitary gland in the sellar region. Topics range from epidemiology, symptoms and signs, imaging, therapeutic

Автор: NoA©mi Barta
Название: The Pituitary Gland and Adrenal Glands: New Research
ISBN: 1536176052 ISBN-13(EAN): 9781536176056
Издательство: Nova Science
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Цена: 149940.00 T
Наличие на складе: Невозможна поставка.
Описание: In The Pituitary Gland and Adrenal Glands: New Research, the authors first discuss pituicytomas, rare primary glial neoplasms that arise in the neurohypophysis (or posterior portion) of the pituitary gland. They typically present with signs and symptoms of a slow growing, non-hormonally active mass of the sellar and suprasellar region, compressing adjacent structures. Following this, the clinical and pathologic features of spindle cell oncocytomas are discussed. Spindle cell oncocytomas are rare tumors, accounting for less than 0.5% of sellar masses. Tumors typically present in adults and most commonly manifest with visual disturbances and pituitary hypofunction. Additionally, the authors review the clinical and pathological features of gangliocytomas, rare benign tumors of the neuroaxis. They are most commonly seen in children and young adults, and most often arise in the cerebellum as part of Cowdens disease, or in the sellar region. The clinicopathologic features of granular tumors, rare neoplasms that most commonly arise in the neurohypophysis or posterior portion of the pituitary gland, are also discussed. This compilation goes on to examine the adrenal glands, paired structures located superior to the kidneys in the retroperitoneal space. Mineralocorticoids, glucocorticoids and adrenal androgens are synthesized respectively in the zona glomerulosa, zona fasciculatis and zona reticularis that make up the cortex, while the inner adrenal medulla produces the catecholamines and peptides. The risk of developing adrenal insufficiency among glucocorticoid users is assessed, and risk factors are identified. Glucocorticoids are widely used for the treatment of various inflammatory conditions and malignancies, as well as after organ transplantation. The closing study explores hypothalamic-pituitary-adrenal axis activation, a potent and complex response to heat stress in domestic livestock. The hypothalamic-pituitary-adrenal axis is activated during stress, which leads to the secretion of cortisol and aldosterone from the adrenal gland.

Автор: E. van Cauter; G. Copinschi
Название: Human Pituitary Hormones
ISBN: 9400982844 ISBN-13(EAN): 9789400982840
Издательство: Springer
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Цена: 81050.00 T
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