Safety of Biologics Therapy, Brian A. Baldo

Автор: Baldo
Название: Safety of Biologics Therapy
ISBN: 3319304704 ISBN-13(EAN): 9783319304700
Издательство: Springer
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Цена: 149060.00 T
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Описание: This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.

Автор: W.-H. Boehncke; H.H. Radeke
Название: Biologics in General Medicine
ISBN: 364243567X ISBN-13(EAN): 9783642435676
Издательство: Springer
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Цена: 158380.00 T
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Описание: The idea for this book was born during the symposium on biologics organized by ZAFES (Center for Drug Research, Development and Safety at the University of Frankfurt am Main) in September 2005. Highly distinguished researchers special- ing in the field of biologics had gathered together to exchange information on this relatively new subject. Realizing that this symposium was one of the few sources of condensed information on biologics, it became obvious that we had to create a means of informing an interested wider circle of scientists and especially general c- nicians. Therefore, the editors of this book suggested to the researchers at the symposium andalsotoprominent scientists andcliniciansinvolvedinthe developmentand application of biologics as their major field of interest the idea of assembling this compendium. We received an overwhelmingly positive response – thankfully also from the publisher – most being more than willing to support this innovative project with highly relevant chapters on the latest state of the art. As we were eager to fill the information gap with up-to-date knowledge, the project had to be finished within the shortest time possible. To all experienced with editing this was obviously a ch- lengeand we areverythankfultoall thecontributorsthatour timeline hadtobe extended by only a few months. This book represents a collection of the most recent knowledge on biologics written by people who have been active in the field for many years. Wolf-Henning Boehncke Heinfried H. Radeke Contents 1 Introduction: Definition and Classification of Biologics W. -H. Boehncke, H. H. Radeke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Автор: Manmohan Singh
Название: Novel Approaches and Strategies for Biologics, Vaccines and Cance
ISBN: 0124166032 ISBN-13(EAN): 9780124166035
Издательство: Elsevier Science
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Цена: 176290.00 T
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Описание: Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. Written by leading authors across academia and industry, this book covers important topics such as unique drug delivery devices, non-parenteral delivery trends, novel approaches to the treatment of cancer, immunotherapy and more. It includes real-world cases and examples which highlight formulations with therapeutic proteins, monoclonal antibodies, peptides and biobetters, as well as cases on novel vaccines formulations including evolving pathogens, novel modalities of vaccines, universal vaccines. This book is a thorough and useful resource on the development of novel biologics, vaccines and cancer therapies.

Автор: Cheifetz
Название: Treatment of Inflammatory Bowel Disease with Biologics
ISBN: 3319868233 ISBN-13(EAN): 9783319868233
Издательство: Springer
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Цена: 83850.00 T
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Описание: This second edition is primarily for trainees and junior pediatric residents in adult rheumatology who will be seeing pediatric patients with rheumatic diseases. The short chapters have clear tables and many clinical photos to demonstrate key features of diseases and allow the reader to be well informed when seeing patients with rheumatic diseases.