Huntington`s Disease, Sophie V. Precious; Anne E. Rosser; Stephen B. Dun

Автор: Precious
Название: Huntington`s Disease
ISBN: 1493978241 ISBN-13(EAN): 9781493978243
Издательство: Springer
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Цена: 204040.00 T
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Описание: This detailed book provides a laboratory manual and guidebook for the selection, implementation, and interpretation of a wide range of techniques in contemporary use in leading laboratories engaged in Huntington’s disease (HD) research worldwide. Only by understanding the pathology and pathogenic process at the fundamental molecular and cellular level can the research community expect to be able to slow or halt the disease process, repair the damage, and develop novel effective therapies to treat the symptoms of this condition, thus this volume collects the practical knowledge of its authors. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Bird Thomas D.
Название: Can You Help Me?: Inside the Turbulent World of Huntington Disease
ISBN: 0190684224 ISBN-13(EAN): 9780190684228
Издательство: Oxford Academ
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Цена: 23220.00 T
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Описание: This book describes the framework of the next generation of Business Information Services Library, BiSL(R). BiSL Next is a public domain standard for business information management with guiding principles, good practices and practical templates. It offers guidance for digitally engaged business leaders and those who collaborate with them, with the ultimate goal to improve business performance through better use of information and technology.Twelve elements - four drivers, four domains and four perspectives - are the basis of the guidance in BiSL Next. Target audience of this book are business managers, business information managers, business analysts, CIO`s and IT managers, as well as consultants in this field.While describing the twelve elements, the book offers them insight in the best way to manage, execute and profit from business information management in their enterprise. The book is also the official literature for the BiSL(R) Next Foundation exam.

Автор: G. Bruyn; M.R. Hayden
Название: Huntington`s Chorea
ISBN: 1447113101 ISBN-13(EAN): 9781447113102
Издательство: Springer
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Цена: 81050.00 T
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Описание: It is a pleasure to send Dr. Hayden's monograph on its way to as yet unknown but hopefully widespread destinations with all the valedictions a Foreword may contain. Since I met the author in Cape Town in 1978 I have been struck, on numerous occasions, by the fortuitous combination of an inquisitive mind, a creative drive, a sharp awareness of the historical and social setting of phenomena, and a solid discipline which his personality displays behind a good-natured laugh. If a tree is known by its fruits, both Dr Hayden's PhD thesis and the present monograph afford quite an insight into the auctor intellectualis. The amalgamation of the terrible mise ry behind scientifIc facts and the elegantly artistic presentation of this book will leave none of its readers unperturbed. It reminds me of Nietzsche's 'Denn das Sch ne ist nichts als des Schrecklichen Anfang, und wir bewundern es so weil es gelassen verschm ht uns zu zerst ren' (Beauty is but Horror's beginning, and we admire it because it resignedly spurns to destroy us). The book is a denial, a testimony against Juvenal's spurious 'Sternmata quid faciunt ... ' (of what value are pedigrees). For it is the very genetical prolongation of misery over the centuries that brought Huntington's chorea to South Africa, Australia and the USA from the shores of sea-faring seventeenth-century England and Holland.

Автор: Hoa Huu Phuc Nguyen; M. Angela Cenci
Название: Behavioral Neurobiology of Huntington`s Disease and Parkinson`s Disease
ISBN: 3662524120 ISBN-13(EAN): 9783662524121
Издательство: Springer
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Цена: 130590.00 T
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Описание: Motor dysfunction and cognitive impairment are major symptoms in both Huntington`s Disease (HD) and Parkinson`s Disease (PD). This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.

Автор: Hoa Huu Phuc Nguyen; M. Angela Cenci
Название: Behavioral Neurobiology of Huntington`s Disease and Parkinson`s Disease
ISBN: 3662463431 ISBN-13(EAN): 9783662463437
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.

Автор: Sherman Howell
Название: Living with Huntingtons Disease: Challenges, Perspectives and Quality of Life
ISBN: 1536167290 ISBN-13(EAN): 9781536167290
Издательство: Nova Science
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Цена: 89750.00 T
Наличие на складе: Невозможна поставка.
Описание: Living with Huntingtons Disease: Challenges, Perspectives and Quality of Life first discusses the variety of sleep disorders in Huntingtons Disease, as well as how sleep quality can be associated with other important clinical symptoms. Although Huntingtons disease is categorized as a movement disorder, the wide range of non-motor symptoms including cognitive impairment and behavioral abnormalities are considered by patients and their caregivers to be just as disabling as the motor symptoms. As such, the authors explore the importance of symptomatic treatment of Huntingtons disease-related symptoms. Following this, the emotional and communicational issues in Huntingtons disease and their interrelations are examined, including depressive symptomatology, anxiety, helplessness or anger, as well as verbal and non-verbal communication and assistive technology. Lastly, the authors describe current trends and efforts in gene therapy techniques and the improvements in health conditions of Huntingtons disease patients and their families.

Автор: Watt
Название: A Clinico-Genetic Study of Psychiatric Disorder in Huntington`s Chorea
ISBN: 0521459834 ISBN-13(EAN): 9780521459839
Издательство: Cambridge Academ
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Цена: 40130.00 T
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Описание: This report presents the findings of a study of people affected by Huntington`s chorea and their unaffected relatives, and in particular, of the incidence of functional psychiatric disorder of various types. It also considers the future prospects of the genetics of the condition

Автор: Huntington George S.
Название: The Anatomy of the Human Peritoneum and Abdominal Cavity
ISBN: 6057876784 ISBN-13(EAN): 9786057876782
Издательство: Неизвестно
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Цена: 27580.00 T
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Описание:

PREFACE

In the following pages an attempt has been made to emphasize the value of Embryology and Comparative Anatomy in elucidating the difficult and often complicated morphological problems encountered in the study of human adult anatomy.

Moreover, in addition to the direct advance in the method and scope of anatomical teaching afforded by these aids, it is further hoped that the broader interpretation, both of structure and function, obtained by ontogenetic and phylogenetic comparison, will impart an interest to the study of adult human morphology, such as the subject, considered solely in the narrow field of its own limitations, could never arouse.

The book represents part of the course in visceral anatomy as developed during the past fourteen years at Columbia University. The sections dealing with the morphology of the vertebrate ileo-colic junction and with the structural details of the human c cum and appendix are considered somewhat more fully, as warranted by the extensive material available. The illustrations are for the greater part taken from preparations in the Morphological Museum of the University.

Wherever practicable the direct photographic reproduction of the actual preparation is given. In the case of preparations not suitable for this purpose, careful drawings have been made which offer in every instance a faithful and correct interpretation of the conditions presented by the actual object. A number of the embryonic illustrations are taken from the standard text-books on the subject, due credit being given to their source. I desire to express my sincere thanks to Dr. Edward Leaming, of the Department of Photography and to Mr. M. Petersen, artist of the Anatomical Department of the University, for their skilful and thoroughly reliable work in the preparation of the illustrations.

George S. Huntington.