Endocannabinoids, Roger G. Pertwee

Название: Endocannabinoids
ISBN: 0367391910 ISBN-13(EAN): 9780367391911
Издательство: Taylor&Francis
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Цена: 65320.00 T
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Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease

Endocannabinoids: The Brain and Body's Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system's association across all of human physiology, including the immune, endocrine, and reproductive systems.

With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS's relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer.

The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology.

Автор: Miriam Melis
Название: Endocannabinoids and Lipid Mediators in Brain Functions
ISBN: 3319573691 ISBN-13(EAN): 9783319573694
Издательство: Springer
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Цена: 158380.00 T
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- The Endocannabinoid System in Leptin-Driven Changes of Orexinergic Signalling Under Physiological and Pathological Conditions.- How CB1 Receptor Activity and Distribution Contribute to Make the Male and Female Brain Different Towards Cannabinoid-Induced Effects.- Endocannabinoids, Stress, and Negative Affect.- Cell-Autonomous Endocannabinoid Production Shapes Polarized and Dynamic Distribution and Signaling Patterns of Cannabinoid CB1 Receptors in Neurons.- Endocannabinoid-Dependent Synaptic Plasticity in Striatum.- Lipid Mediators in the Regulation of Emotions, Memory and Cognitive Functions.- The Endocannabinoid System in Prefrontal Synaptopathies.- Cannabinoids and Mitochondria.- Endocannabinoids and Lipid Mediators in Brain Function.- Endocannabinoid Signaling in Reward and Addiction: From Homeostasis to Pathology.- Roles of N-Acylethanolamines in Brain Functions and Neuropsychiatric Diseases.- Mast Cells and Glia as Targets for the Anandamide Congener Palmitoylethanolamide, and Anti-Inflammatory and Neuroprotective Lipid-Signaling Molecule.

Автор: Van Bockstaele
Название: Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders
ISBN: 1461479398 ISBN-13(EAN): 9781461479390
Издательство: Springer
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Цена: 174150.00 T
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Описание: This book offers current information on advances in the field of endocannabinoid signaling and potential therapeutic applications with a particular emphasis on monoaminergic circuits.

Автор: Melanie E. M. Kelly, Christian Lehmann, Juan Zhou
Название: The Endocannabinoid System in Local and Systemic Inflammation
ISBN: 1615047727 ISBN-13(EAN): 9781615047727
Издательство: Mare Nostrum (Eurospan)
Цена: 79380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the role of the endocannabinoid system in local and systemic inflammation, with individual chapters written by experts in the field of cannabinoid research and medicine. The topics explore the actions of the endocannabinoid system on the immune system, including neuroinflammation in autoimmune disorders such as multiple sclerosis, and in neurodegenerative disorders such as Huntington's and Alzheimer's, as well as local and systemic inflammatory conditions affecting organs including the eye (uveitis and corneal inflammation), the bladder (interstitial cystitis), pancreas (diabetes), cardiovascular system (stroke), joints (arthritis), and sepsis. The objective of this book is to provide knowledge transfer on the use of cannabinoids in inflammatory disease by critically examining preclinical and clinical research on the immunomodulatory actions of the endocannabinoid system, with specific emphasis on the actions of cannabinoids in diseases where inflammation is a prominent component. By drawing these results together, we seek to provide further understanding of the complexities of endocannabinoid system modulation of immune function and identify potential uses and limitations for cannabinoid-based therapeutics.

Автор: Elisabeth J. Van Bockstaele
Название: Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders
ISBN: 1489996087 ISBN-13(EAN): 9781489996084
Издательство: Springer
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Цена: 148010.00 T
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Описание: This book offers current information on advances in the field of endocannabinoid signaling and potential therapeutic applications with a particular emphasis on monoaminergic circuits.

Автор: Dave Kendall; Stephen Alexander
Название: Behavioral Neurobiology of the Endocannabinoid System
ISBN: 3642260780 ISBN-13(EAN): 9783642260780
Издательство: Springer
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Цена: 191550.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The endocannabinoid signaling system is a key modulator of central nervous function. This volume, essential reading for interested neuroscientists, provides in-depth coverage of the roles of the endocannabinoid signaling system in the neurobiology of behavior.