Human Genetics and Genomics: A Practical Guide, Bahar Taneri, Esra Asilmaz, T?rem Delikurt, Pembe

Автор: Eberhard Passarge
Название: Color Atlas of Genetics, 5 еd.
ISBN: 3132414409 ISBN-13(EAN): 9783132414402
Издательство: Thieme Verlagsgruppe
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Цена: 71560.00 T
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Ever since the International Human Genome Project achieved its extraordinary goal of sequencing and mapping the entire human genome, represented by approximately 3 billion base pairs, with its far-reaching implications for understanding the causes of human genetic disorders and their diagnosis, progress in the field has not slowed down.

In the fifth edition of the bestselling Color Atlas of Genetics, readers will be rewarded with a complete and current overview of the field, with an emphasis on the interface between fundamental principles and practical applications in medicine and the role of signaling pathways in causing diseases.

Using the acclaimed Flexibook format designed for easy visual learning and retention, the atlas is invaluable for students, clinicians, and scientists interested in staying up to date in this fast-evolving area.

New fully illustrated topics in the revised fifth edition of the atlas include:

• An overview of disorders resulting from structural changes of the genome (genomic disorders)
• Abnormal imprinting patterns
• Examples of impaired signal pathways (laminopathies, fibrillinopathies, cohesinopathies, and others)
• The CRISPR-Cas system
• Genetic features of the aging processes
• Disorders due to rearrangements of chromatin in the cell nucleus, and others

With almost 200 stunning color plates explained by concise texts on the opposite pages, including tables presenting useful data, a glossary of terms, key references, and online resources, the atlas presents clear and accessible concepts. It is an excellent refresher for investigators in any field of medicine or biology.

Автор: Robert L. Nussbaum, Roderick R. McInnes
Название: Thompson & Thompson Genetics in Medicine
ISBN: 1437706967 ISBN-13(EAN): 9781437706963
Издательство: Elsevier Science
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Цена: 36450.00 T
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Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders.

• Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics.
• Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies.
• Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos.

• Immerse yourself in updated graphics, full-color text, illustrations, line diagrams, and clinical photos of genetic diseases.
• Explore the latest genetic content available in order to remain up to date on the most current trends in the field.
• Take advantage of a double-page clinical case study section that demonstrates and reinforces general principles of disease inheritance, pathogenesis, diagnosis, management, and counseling.
• Enhance your critical thinking skills and better retain information. Each chapter ends with up to 5 quick genetic problems related to what has just been reviewed, with answers provided in the back of the book.
• Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. You'll also access USMLE-style and multiple choice questions.

Автор: Gangane
Название: Human Genetics, 5e
ISBN: 8131248704 ISBN-13(EAN): 9788131248706
Издательство: Elsevier India
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Цена: 6500.00 T
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Описание: The present edition is updated according to the syllabus for undergraduates, recommended by the Medical Council of India. This examination-friendly-book written in simple to-the-point is also useful for postgraduates, immunologists and geneticists. Salient Features Revision in chapters on molecular genetics, chromosomal aberrations, modes of inheritance, population genetics, and genetic counselling to meet current advances in the field Inclusion of new features such as learning objectives facilitate to focus on important facts and key words that form SAQ's in examinationsAddition of new figures and improvement in earlier diagrams to support the utility of this book Additional Feature Complimentary access to enhanced e-book along with online videos.

Автор: Passarge
Название: Genetics, Color Atlas
ISBN: 3131003634 ISBN-13(EAN): 9783131003638
Издательство: Thieme Verlagsgruppe
Цена: 38530.00 T
Наличие на складе: Нет в наличии.
Описание: A remarkable achievement by a single author...concise but informative...No geneticist or physician interested in genetic diseases should be without a copy of this remarkable edition." --American Journal of Medical GeneticsMore than ever, a solid understanding of genetics is a fundamental element of all medical and scientific educational programs, across virtually all disciplines. And the applications--and implications--of genetic research are at the heart of current medical scientific debates. Completely updated and revised, The Color Atlas of Genetics is an invaluable guide for students of medicine and biology, clinicians, and anyone else interested in this rapidly evolving field. The latest edition of this highly praised atlas retains several popular features, such as the accessible layout and logical structure, in addition to many novel features and 20 completely new color plates on new topics, including:-Cell-to-cell communication, including important signaling and metabolic pathways-Taxonomy of living organisms ("tree of life")-Epigenetic modifications in chromatin-Apoptosis-RNA interference (RNAi)-Comparative genomic hybridization -Origins of cancer-Principles of gene and stem cell therapy, etc.With more than 200 absorbing full-color plates concisely explained on facing pages, the atlas offers readers an easy-to-use, yet remarkably detailed guide to key molecular, theoretical, and medical aspects of genetics and genomics. Brief descriptions of numerous genetic diseases are included, with references for more detailed information.Readers will find that this incomparable book presents a comprehensive picture of the field from its fascinating history to its most advanced applications.Contents Overview:-Introduction-Chronology: important dates in genetics-Part I. Fundamentals: Molecular Basis of Genetics, Prokaryotic Cells and Viruses, Eukaryotic Cells, Mitochondrial Genetics, Formal Genetics, Chromosomes, Regulation and Expression of Genes-Part II. Genomics-Part III. Genetics and Medicine: Cell-to-Cell Interactions, Lysosomes and LDL Receptor, Genes in Embryonic Development, Immune System, Oxygen and Electron Transport, Homeostasis, Maintaining Cell and Tissue Shape, Mammalian Sex Determination and Differentiation, Atypical Inheritance Pattern, Karyotype--Phenotype Correlation, A Brief Guide to Genetic Diagnosis-Guide to Genetic Diagnosis and Map of Important Human Genetic Diseases-Appendix: Supplementary Data in Tables-Glossary

Автор: Naumova Anna K & Taketo-Hosotani Teruko
Название: Epigenetics In Human Reproduction And Development
ISBN: 9813144262 ISBN-13(EAN): 9789813144262
Издательство: World Scientific Publishing
Цена: 121440.00 T
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Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.

Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Автор: Michael Dean
Название: From Gene to Therapy: Understanding Human Disease through Genetics
ISBN: 1615047719 ISBN-13(EAN): 9781615047710
Издательство: Mare Nostrum (Eurospan)
Цена: 50120.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Lecture provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases will be provided, drawing on the author's research. Topics include examples from simple Mendelian diseases, such as cystic fibrosis, inherited cancers, oncogenes activated by chromosomal translocations, host genes involved in infectious disease, genes identified via genomewide association studies, pathogens causing cancer, and gene families contributing to multiple diseases. For each example, historical details will be provided as background for readers to understand the context and process of the discoveries, technologies explained, and current understanding and treatment implications detailed.

Автор: Hong Jiang; Ming Liu
Название: Heart Genomics
ISBN: 9811314284 ISBN-13(EAN): 9789811314285
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a series of important breakthroughs in various heart diseases. Applying unbiased genomics, combined with a disease-focused and hypothesis-driven approach, represents a promising way to advance our understanding of cardiac diseases. The book offers an important reference work on introducing genomics in heart disease for all scientists and graduate students whose work involves genomics and cardiology, as well as for clinical physicians.

Автор: Mario Cesar Lopez-Camarillo
Название: Comparative Genomics in Neglected Human Parasites
ISBN: 162417874X ISBN-13(EAN): 9781624178740
Издательство: Nova Science
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Цена: 195350.00 T
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Описание: To date, parasite diseases still affect millions of people world-wide, mainly in developing countries. The recent sequencing of parasite genomes opened a new era in parasitology research since the acquisition of new genomic data, providing a useful tool to analyse and compare gene structure, location and characteristics from different species to study evolution and gene function. This book is a collection of the recent findings of international experts in modern parasitology, computational biology, evolutionary biology, and genetics. It includes specific data on the current knowledge and understanding of genome organisation, dynamic and function for Plasmodium falciparum, Trypanosoma spp., Leishmania spp., Trichomonas vaginalis, Giardia lamblia, Entamoeba histolytica and Microsporidium, which represent the main causes of parasitic infections in humans. This book will be an essential reference for all parasitologists and scientists, as well as researchers, postdoctoral fellows and graduate students in computational biology, evolutionary biology, and genetics.

Автор: Shirley V. Hodgson; William D. Foulkes; Charis Eng
Название: A Practical Guide to Human Cancer Genetics
ISBN: 1447171721 ISBN-13(EAN): 9781447171720
Издательство: Springer
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Цена: 102480.00 T
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Описание: This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. There is information about the genes causing Mendelian cancer predisposing conditions and their mechanism of action.

Автор: Korf
Название: Human Genetics and Genomics. 2006.IE
ISBN: 0632046562 ISBN-13(EAN): 9780632046560
Издательство: Wiley
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Цена: 34840.00 T
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Описание: "Human Genetics and Genomics, 3rd edition", the new re-edition of the classic textbook "Human Genetics: A Problem-Based Approach", merges basic genetic principles with clinical applications of genetics in medical practice. By presenting the core concepts of human genetics while maintaining an emphasis on a problem-based learning and clinical approach, the third edition of "Human Genetics and Genomics" acts both as a textbook for genetics courses, and a bridge into the clinical environment. The features include enhanced emphasis on microbiology content, a chapter devoted to laboratory techniques, and a vast array of new pedagogy, such as: recommended readings for each chapter; "Clinical snapshots" covering major genetic disorders and integrating a clinical approach; ethics boxes covering ethical implications in genetics; key points at the beginning of each chapter for a quick summary and Question-Answers at the end of each chapter for self-testing; and "Hot topics" sections at the ends of chapters covering new and emerging areas in genetics.

Автор: Hodgson Shirley V
Название: Practical Guide to Human Cancer Genetics
ISBN: 1447123743 ISBN-13(EAN): 9781447123743
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. There is information about the genes causing Mendelian cancer predisposing conditions and their mechanism of action.

Автор: Shirley Hodgson
Название: A Practical Guide to Human Cancer Genetics
ISBN: 052168563X ISBN-13(EAN): 9780521685634
Издательство: Cambridge Academ
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Цена: 102430.00 T
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Описание: This is a comprehensive guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. This 2006 edition was fully up-dated with more molecular, screening and management information. It covers risk analysis, predictive testing and genetic counselling for individuals with a family history of cancer.