This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Haines Duane E. Название: Fundamental Neuroscience for Basic and Clinical Applications ISBN: 0323396321 ISBN-13(EAN): 9780323396325 Издательство: Elsevier Science Рейтинг: Цена: 86450.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Using a rigorous yet clinically-focused approach, Fundamental Neuroscience for Basic and Clinical Applications, 5th Edition, covers the fundamental neuroscience information needed for coursework, exams, and beyond. It integrates neuroanatomy, pharmacology, and physiology, and offers a full section devoted to systems neurobiology, helping you comprehend and retain the complex material you need to know.
Highlights clinical content in blue
throughout the text, helping you focus on what you need to know in the clinical environment.
Presents thoroughly updated information in every chapter, with an emphasis on new clinical thinking as related to the brain and systems neurobiology.
Features hundreds of correlated state-of-the-art imaging examples, anatomical diagrams, and histology photos - nearly half are new or improved for this edition.
Pays special attention to the correct use of clinical and anatomical terminology, and provides new clinical text and clinical-anatomical correlations.
Автор: Kalet Ira J. Название: Principles of Biomedical Informatics, 2 ed ISBN: 0124160190 ISBN-13(EAN): 9780124160194 Издательство: Elsevier Science Рейтинг: Цена: 83080.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides a treatment of the deep computational ideas at the foundation of the field. This book includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: tree structured data, interval trees, and time-oriented medical data and their use.
Автор: Olinda Timms Название: Biomedical Ethics. 2 ed ISBN: 813125965X ISBN-13(EAN): 9788131259658 Издательство: Elsevier India Рейтинг: Цена: 5590.00 T Наличие на складе: Есть Описание: Each chapter focuses on a single area in a simple narrative. Illustrative case reports and case studies of ethical dilemmas are provided with points for reflection/discussion. In step with the curriculum in Medical Ethics already established in several medical colleges.
The chapters can be used to develop modules in a medical ethics program. Additional resources (titles of relevant films, readings, and references) are provided. The chapters have been linked to the AETCOM modules for easy reference, providing content for teaching modules.
This book provides the resource to create teaching modules in medical ethics. In this way, the book compliments the AETCOM modules and can be used to develop teaching-learning sessions.?
Название: Computational systems bioinformatics - methods and biomedical applications ISBN: 9812707042 ISBN-13(EAN): 9789812707048 Издательство: World Scientific Publishing Рейтинг: Цена: 100320.00 T Наличие на складе: Невозможна поставка. Описание: Computational systems biology (CSB) is a field of research concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. This book introduces the basic principles of CSB.
Автор: Mohamed, Amr Название: Energy Efficiency Of Medical Devices And Healthcare Applications ISBN: 0128190450 ISBN-13(EAN): 9780128190456 Издательство: Elsevier Science Рейтинг: Цена: 105540.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Energy Efficiency of Medical Devices and Healthcare Facilities provides comprehensive coverage of cutting-edge, interdisciplinary research, and commercial solutions in this field. The authors discuss energy-related challenges, such as energy-efficient design, including renewable energy, of different medical devices from a hardware and mechanical perspectives, as well as energy management solutions and techniques in healthcare networks and facilities. They also discuss energy-related trade-offs to maximize the medical devices availability, especially battery-operated ones, while providing immediate response and low latency communication in emergency situations, sustainability and robustness for chronic disease treatment, in addition to high protection against cyber-attacks that may threaten patients' lives. Finally, the book examines technologies and future trends of next generation healthcare from an energy efficiency and management point of view, such as personalized or smart health and the Internet of Medical Things -- IoMT, where patients can participate in their own treatment through innovative medical devices and software applications and tools. The books applied approach makes it a useful resource for engineering researchers and practitioners of all levels involved in medical devices development, healthcare systems, and energy management of healthcare facilities. Graduate students in mechanical and electric engineering, and computer science students and professionals also benefit.
Computational Learning Approaches to Data Analytics in Biomedical Applications provides a unified framework for biomedical data analysis using varied machine learning and statistical techniques. It presents insights on biomedical data processing, innovative clustering algorithms and techniques, and connections between statistical analysis and clustering. The book introduces and discusses the major problems relating to data analytics, provides a review of influential and state-of-the-art learning algorithms for biomedical applications, reviews cluster validity indices and how to select the appropriate index, and includes an overview of statistical methods that can be applied to increase confidence in the clustering framework and analysis of the results obtained.
Автор: Johri, Prashant Название: Computational Intelligence And Its Applications In Healthcare ISBN: 0128206047 ISBN-13(EAN): 9780128206041 Издательство: Elsevier Science Рейтинг: Цена: 149340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Computational intelligence is the study of the design of intelligent agents. An intelligent agent is a system that acts intelligently - it does what it thinks appropriate for its circumstances and its goal, it is flexible to changing environments and changing goals, it learns from experience, and it makes appropriate choices given perceptual limitations and finite computation. Computational intelligence paradigms offer many advantages in maintaining and enhancing the field of healthcare. Computational Intelligence and Its Applications in Healthcare presents rapidly growing application areas of computational intelligence to healthcare systems, including intelligent synthetic characters, man-machine interface, menu generators, analysis of user acceptance, pictures archiving and communication systems.
Автор: Jinglong Wu Название: Biomedical Engineering and Cognitive Neuroscience for Healthcare: Interdisciplinary Applications ISBN: 1466621133 ISBN-13(EAN): 9781466621138 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 238390.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Brings together researchers and practitioners, including medical doctors and health professionals, to provide an overview of the studies of cognitive neuroscience and biomedical engineering for healthcare. This book aims to be a reference for researchers in the related field aiming to bring benefits to their own research.
Автор: Niklaus Baltzer Название: Precious Metals for Biomedical Applications, ISBN: 0857094343 ISBN-13(EAN): 9780857094346 Издательство: Elsevier Science Рейтинг: Цена: 167310.00 T Наличие на складе: Поставка под заказ. Описание: Precious metals and semi-precious metals have been used in medicine for many years. The properties of these metals and their alloys makes them suitable for an increasing number of medical applications. This book provides readers with a useful review of this group of materials` unique properties and applications.
Автор: Picart Название: Layer-by-Layer Films for Biomedical Applications ISBN: 3527335897 ISBN-13(EAN): 9783527335893 Издательство: Wiley Рейтинг: Цена: 158400.00 T Наличие на складе: Поставка под заказ. Описание: The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance.
Functional Nanostructured Interfaces for Environmental and Biomedical Applications provides an overview on the characteristics of nanostructured interfaces and their processing technologies for a wide range of applications in the sensing, photocatalytic and bioengineering areas. The book focuses on the fundamentals of multifunctional nanostructured interfaces and their associated technologies, including versatile technologies, such as colloidal lithography, scanning probe techniques and laser nanostructuring, which can be used to obtain multifunctional 2D and 3D nanotextured interfaces. The book provides multidisciplinary chapters, summarizes the current status of the field, and covers important scientific and technological developments made over past decades.
As such, it is an invaluable reference to those working in the design of novel nanostructured materials.
Covers emerging applications of nanostructured interfaces, with a focus on sensing, bio-related and environmental applications
Provides detailed and up-to-date overviews on the characteristics of nanostructured interfaces and their processing technologies, including materials from multifunctional graphene, to extremophile materials
Includes information about versatile technologies, such as colloidal lithography, scanning probe techniques and laser nanostructuring, all of which can all be used to obtain multifunctional 2D and 3D nanotextured interfaces
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