Название: Colorectal cancer: prevention, diagnosis and treatment ISBN: 1536165980 ISBN-13(EAN): 9781536165982 Издательство: Nova Science Рейтинг: Цена: 77080.00 T Наличие на складе: Невозможна поставка. Описание: Adenocarcinoma is the predominant malignancy found in the colon and rectum. Colorectal cancer is the third most common cancer diagnosed in the developed world with a high incidence of mortality and morbidity. The average five-year survival rate remains poor at 55%, although the development of new drugs has improved the survival rate of colorectal cancer patients. The prognosis of colorectal cancer remains poor in spite of the development of novel therapeutic strategies. Human colorectal cancer represents a heterogeneous group of diseases, and its molecular classification is increasingly important. Characterization of novel biomarker targets may lead to prolong the survival rate of colorectal cancer. Biomarkers may have a potential role in screening, diagnosis, prognosis and monitoring disease. Mutations in the KRAS gene in ~ 40% of tumors have been reported to be induced by genetic and epigenetic alterations. This book, comprised of four chapters, introduces recent topics regarding colorectal cancer, and provides recent highlighted information concerning prevention, diagnosis and treatment. This book will be of interest to undergraduate and graduate students, biomedical researchers, and medical doctors focused on the fields of molecular and cellular biology, medical sciences, and clinical challenges.
Автор: John D. Potter; Noralane M. Lindor Название: Genetics of Colorectal Cancer ISBN: 1441918655 ISBN-13(EAN): 9781441918659 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume explores the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers.
Автор: Cameron Название: Atlas of Gastrointestinal Surgery (Volume 2) ISBN: 1607950278 ISBN-13(EAN): 9781607950271 Издательство: Mare Nostrum (Eurospan) Цена: 262410.00 T Наличие на складе: Невозможна поставка. Описание: Once again, Doris Graber brings readers the most thought-provoking and recent scholarship about the actual power of the media in the real world of politics. With approximately 35 essays, half of them new to this edition, the selections reflect the latest changes in American politics, in American media platforms, and in the interactions between political actors and journalists.
Автор: Herring Lancel Название: Pathogenesis, Diagnosis and Management of Colorectal Cancer ISBN: 1632427486 ISBN-13(EAN): 9781632427489 Издательство: Неизвестно Рейтинг: Цена: 150200.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Colorectal cancer refers to the cancer of the rectum or colon. Its symptoms are a change in bowel movement, weight loss, blood in the stool and a persistent state of exhaustion. Consumption of processed meat, red meat and alcohol, lack of physical activity, obesity and smoking are considered risk factors that contribute to the occurrence of this cancer. It can be diagnosed by performing a colonoscopy or sigmoidoscopy, or by a microscopical examination of a tissue sample. A referral medical imaging determines the spread or localization of the disease. Colorectal cancer can be treated through a combination of chemotherapy, radiation therapy, surgery and targeted therapy. Depending on the stage of the tumor and patient's health, treatment can be palliative or done with the intent to cure. The topics covered in this extensive book deal with the core aspects of colorectal cancer. Its aim is to present researches pertaining to the pathogenesis, diagnosis and management of colorectal cancer. It will prove to be immensely beneficial to students and researchers in this field.
Автор: Qin Название: Multidisciplinary Management of Liver Metastases in Colorectal Cancer ISBN: 9401777535 ISBN-13(EAN): 9789401777537 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery. This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecular diagnostics, marker screening, imaging technology, surgery, chemotherapy and prevention, etc. It provides professionals with up-to-date and comprehensive information on colorectal liver metastases. This book is relevant for senior surgeons and physicians working in oncology, general surgery, chemotherapy, digestive medicine, liver medicine and hepatic surgery.
Автор: Peter Jordan Название: Targeted Therapy of Colorectal Cancer Subtypes ISBN: 3030027708 ISBN-13(EAN): 9783030027704 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. Recent years have increased significantly our understanding of the genetic alterations that can underlie CRC, but also unraveled the molecular heterogeneity of the disease. Although a simple correlation between genetic pathways, histopathological features and clinical outcome cannot be established, the heterogeneity of CRC is also an opportunity for the development of targeted therapeutic approaches, able to treat an individual tumor with higher efficiency and less toxic side effects. One CRC subtype is characterized by high mutation rates (MSI-H), DNA methylation changes (CIMP-H), mutation in the BRAF oncogene and occurrence of serrated adenomas in the proximal colon. Other groups prevail in the distal colon and consist of either adenomatous polyps with chromosomal aberrations (CIN) and WNT pathway activation, or carry frequent KRAS mutation and metabolic deregulation, or have strong mesenchymal and infiltrative characteristics. Characterization of driver-mutation events in these CRC subgroups has led to the development of specific drugs targeting, for example, the MAPK pathway, but initial clinical trials have revealed unexpected response rates. The collection of chapters in this volume address the biology of specific CRC subtypes and how these may be targeted to improve precision therapy and clinical benefit for the patients.
Автор: Waqar Ahmed Qureshi Название: Diagnosis and Management Guide for Anorectal Disease: A Clinical Reference ISBN: 1630914924 ISBN-13(EAN): 9781630914929 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 132130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Many gastroenterologists are presented with patients complaining of one or more of several anorectal symptoms. Dr. Waqar Ahmed Qureshi states that most of these problems can be successfully treated non-surgically. This book reviews a number of diseases that gastroenterologists should be able to effectively manage in their office.
Автор: Bleiberg Название: Colorectal Cancer ISBN: 185317808X ISBN-13(EAN): 9781853178085 Издательство: Informa Рейтинг: Цена: 204190.00 T Наличие на складе: Нет в наличии. Описание: Bringing together a strong international team comprised of surgeons, medical oncologists, and radiation therapists, this book presents a detailed discussion of all aspects of colorectal cancer. The authors offer a critical review of the various studies on the association of molecular markers with prognosis and response to therapy. They describe and compare the new surgical approaches for treatment of rectal cancer with total excision of the mesorectum with the previous standard of care. The book provides an excellent overview of the current diagnostic and treatment options for colorectal cancer and contains several chapters highlighting genetics and molecular pathology.
Автор: Kim Название: Surgical Treatment of Colorectal Cancer ISBN: 9811338469 ISBN-13(EAN): 9789811338465 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Поставка под заказ. Описание: This book presents an Asian perspective on how the treatment of colorectal cancer can be optimized and standardized in ways that take into account technological advances and the trend towards individually tailored therapy.
Автор: Kees Welvaart; L.H. Blumgart; J. Kreuning Название: Colorectal Cancer ISBN: 9400991606 ISBN-13(EAN): 9789400991606 Издательство: Springer Рейтинг: Цена: 81050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Perhaps the most outstanding new areas discussed and reflected in the proceedings are the possible range and scope of screening techniques, the new possibilities both in treatment and in endoscopic surgery now available as a result of developments in fibre-optic endoscopy, and new approaches and important parameters in staging of the disease.
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