Obesity, Type 2 Diabetes and the Adipose Organ, Cinti

Автор: Cinti
Название: Obesity, Type 2 Diabetes and the Adipose Organ
ISBN: 3319405209 ISBN-13(EAN): 9783319405209
Издательство: Springer
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Цена: 93160.00 T
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Описание: This richly illustrated book provides a detailed description of the gross anatomy, light microscopy, immunohistochemistry, and electron microscopy of the adipose organ, which comprises subcutaneous and visceral fat depots. Findings in mice of differing genetic backgrounds (obesity prone and resistant) and maintained in standard and various physiologic and pathologic conditions are presented. The latter conditions include chronic cold exposure, warm exposure, fasting, pregnancy–lactation, and obesity. Features of the fetal adipose organ are described in a separate chapter, and results from transgenic mice are also presented when relevant. The human adipose organ is addressed in several chapters that include magnetic resonance and fetal findings. Most of the results regarding the adipose organ anatomy in different physiologic conditions are new, and the story of pink adipocytes (white-to-pink transdifferentiation) is quite innovative. The concept of using browning of the adipose organ as a therapeutic tool for obesity must take into consideration the anatomic and morphologic aspects described here, and the study of pink adipocytes could lead to a better comprehension of breast cancer tumor biology. This book will be of interest to all scientists who deal with obesity and related disorders.

Автор: Pfeifer Alexander, Klingenspor Martin, Herzig Stephan
Название: Brown Adipose Tissue
ISBN: 3030105121 ISBN-13(EAN): 9783030105129
Издательство: Springer
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Цена: 186330.00 T
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Описание: The main focus of this book is on brown adipose tissue and its metabolic function. The book provides a timely update on the latest research and shows where the field is heading. Brown adipose tissue (BAT) dissipates energy and has received considerable attention in the last few years, having been re-discovered in adult humans in 2007/9. Moreover, BAT might offer a target for novel therapies to address obesity, a health condition that has reached pandemic dimensions.

Автор: Iacobellis
Название: Epicardial Adipose Tissue
ISBN: 3030405699 ISBN-13(EAN): 9783030405694
Издательство: Springer
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Цена: 79190.00 T
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Описание:

This book is the first authoritative and comprehensive volume dedicated to epicardial adipose tissue (EAT). It provides an up-to-date and highly illustrated synopsis of the anatomical, biomolecular, genetic, imaging features, and clinical applications of EAT and its role in cardiovascular disease.

It relays to the reader a contemporary view of the emerging interplay between the heart and adiposity-related diseases. In addition, this volume discusses the clinical implications and therapeutic targets of EAT in atrial fibrillation, heart failure and coronary artery disease.

Comprehensive yet focused, Epicardial Adipose Tissue: From Cell to Clinic is an essential resource for physicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention.

Автор: Iacobellis Gianluca
Название: Epicardial Adipose Tissue: From Cell to Clinic
ISBN: 3030405729 ISBN-13(EAN): 9783030405724
Издательство: Springer
Цена: 79190.00 T
Наличие на складе: Поставка под заказ.
Описание: Theologies on the Move examines how the experiences of migration and pilgrimage that are created as a result of the pressures of neoliberal capitalism shape theological and religious traditions. Based on these insights, the contributors examine what difference religion can make in a world dominated by the interests of the few rather than the many.

Автор: Franck Mauvais-Jarvis
Название: Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
ISBN: 3319888978 ISBN-13(EAN): 9783319888972
Издательство: Springer
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Цена: 279500.00 T
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Описание: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Автор: Mauvais-Jarvis
Название: Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
ISBN: 3319701770 ISBN-13(EAN): 9783319701776
Издательство: Springer
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Цена: 232910.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases.There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men. 

Автор: Giamila Fantuzzi; Carol Braunschweig
Название: Adipose Tissue and Adipokines in Health and Disease
ISBN: 1627037691 ISBN-13(EAN): 9781627037693
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint.

Автор: Jean-Philippe Bastard; Bruno F?ve
Название: Physiology and Physiopathology of Adipose Tissue
ISBN: 2817805127 ISBN-13(EAN): 9782817805122
Издательство: Springer
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Цена: 186330.00 T
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Описание: The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.

Автор: Giamila Fantuzzi; Carol Braunschweig
Название: Adipose Tissue and Adipokines in Health and Disease
ISBN: 1493956469 ISBN-13(EAN): 9781493956463
Издательство: Springer
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Цена: 139750.00 T
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Описание: The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.

Автор: Faintuch Joel, Faintuch Salomгo
Название: Obesity and Diabetes: Scientific Advances and Best Practice
ISBN: 3030533727 ISBN-13(EAN): 9783030533724
Издательство: Springer
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Цена: 107130.00 T
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Описание: In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy.

Автор: Boris Draznin; Robert Rizza
Название: Clinical Research in Diabetes and Obesity, Volume 2
ISBN: 1617370517 ISBN-13(EAN): 9781617370519
Издательство: Springer
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Цена: 231990.00 T
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Описание: An unprecedented compilation of state-of-the-art advances in clinical research by premier clinical scientists around the world. This volume discusses the methods of clinical research and the interpretation of their results in studies of normal individuals, obese subjects, and patients with diabetes mellitus.

Автор: Christos S. Mantzoros
Название: Obesity and Diabetes
ISBN: 1617376302 ISBN-13(EAN): 9781617376306
Издательство: Springer
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Цена: 241310.00 T
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Описание: International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity.