Автор: Ramkumar Название: Inflammatory Mechanisms in Mediating Hearing Loss ISBN: 3319925067 ISBN-13(EAN): 9783319925066 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Common forms of preventable hearing loss are drug and noise-induced hearing loss which are believed to be produced by a similar mechanism. The generation of reactive oxygen species appears to be a common mechanism mediating hearing loss produced by these different sources. As such, a number of laboratories have focused their research towards identifying the sources of ROS production in the cochlea following administration of chemotherapeutic agents or noise exposure. This led to the identification of ROS generating enzymes, such as xanthine oxidases, nitric oxide synthase, and NADPH oxidases which are activated and/or induced during the development of hearing loss. A consequence of these findings was the implementation of antioxidants in preclinical studies for the treatment of hearing loss. These antioxidants have provided different levels of protection in animal and human studies, but none of these have been approved by the US Food and Drug Administration for the treatment of hearing loss. More recently, it was shown that noise-induced hearing loss was associated with recruitment of inflammatory cells and mediators in the cochlea. This finding would suggest that noise could produce injury to the cochlea which stimulates local and/or circulating inflammatory cells. A similar finding was observed in the cochlea following administration of the anticancer drug, cisplatin. In addition, our laboratory and others have provided a plausible mechanism by which noise or chemotherapeutic agents could stimulate the inflammatory response. Surprisingly, this mechanism involves ROS activation of transcription factors linked to inflammatory processes in the cochlea. These studies have led to the use of anti-inflammatory agents for the treatment of hearing loss. Preliminary studies targeting inflammatory cytokines appear especially promising in preclinical studies. A primary goal of this project is to describe our current understanding of the oxidant hypothesis of noise and drug-induced hearing loss and show how this relates to cochlear inflammation. Several different aspects of the cochlear inflammatory process will be discussed in detail, ranging from the sources of inflammatory cells, chemokines, inflammatory cytokines, and cochlea resident immune cells. Molecular pathways leading to activation of the local inflammatory process will be highlighted and treatment options will be discussed. The relevance of certain clinically used anti-inflammatory interventions, such as trans-typmanic steroids will also be discussed. Furthermore, we will examine recent patents focusing on the use of anti-inflammatory agents for the treatment of drug and noise-induced hearing loss.
Автор: Valerie Newton Название: Prevention of Hearing Loss ISBN: 1619427451 ISBN-13(EAN): 9781619427457 Издательство: Nova Science Рейтинг: Цена: 299890.00 T Наличие на складе: Невозможна поставка. Описание: Hearing loss is a chronic and often lifelong disability that can cause profound damage to the development of speech, language, and cognitive skills in children, especially when commencing before the critical period of language development in infancy.
Автор: Mirko Tos Название: Volume 4: Surgical Solutions for Conductive Hearing Loss ISBN: 3131216417 ISBN-13(EAN): 9783131216410 Издательство: Thieme Verlagsgruppe Цена: 159650.00 T Наличие на складе: Нет в наличии. Описание: In this book the best surgical solutions for conductive hearing loss due to ossicular fixations are thoroughly described and discussed. The first section covers thympanosclerosis, collating all knowledge on the pathogenesis and pathology of this obscure condition, as well as the surgical methods used in fixation of the ossicular chain, when caused by myringosclerosis and tympanosclerosis.The second section covers postinflammatory, posttraumatic, and postoperative bony fixations of the ossicular chain. In the third section, the voluminous topic of otosclerosis, in particular the evolution of stapes surgery, the various stapedectomy and stapedotomy methods, and the complications of surgery for otosclerosis, are covered in great detail. This section also includes the problems that are encountered in otosclerosis surgery when the ear has been affected with chronic otitis.In the fourth section, congenital ossicular fixations and defects are covered along with some new aspects on the classification and embryology of these problems.For all topics, there is in-depth discussion of the pathogenesis and pathology of the diseases in question. Excellent hand-drawn illustrations provide a level of detail and comprehension not attainable through photography.This book will cover tympanosclerotic, bony, and fibrous fixations, retractions, atelectasis, secretory and adhesive otitis, ventilation problems of the middle ear, cholesteatoma in the tympanic cavity and more!
Автор: Duncan Jill, Rhoades Ellen A., Fitzpatrick Elizabe Название: Auditory (Re)Habilitation for Adolescents with Hearing Loss: Theory and Practice ISBN: 0195381408 ISBN-13(EAN): 9780195381405 Издательство: Oxford Academ Рейтинг: Цена: 93990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Presenting an evidence-based approach to auditory (re)habilitation for adolescents with hearing loss, this book provides professionals with theoretical and practical strategies for intervention, targeting a historically overlooked population.
Автор: Schraer-Joiner Lyn E. Название: Music for Children with Hearing Loss: A Resource for Parents and Teachers ISBN: 0199855838 ISBN-13(EAN): 9780199855834 Издательство: Oxford Academ Рейтинг: Цена: 35890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is a comprehensive and hands-on guide to working with deaf and hard-of-hearing children within and outside of the music classroom, balancing a technical overview of hearing loss with relevant music lessons, teaching practices, resources, and research promoting musical experiences for children who are deaf and hard-of-hearing.
Автор: Brian C. J. Moore Название: Cochlear Hearing Loss: Physiological, Psychological and Technical Issues ISBN: 047051633X ISBN-13(EAN): 9780470516331 Издательство: Wiley Рейтинг: Цена: 91820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Since the first edition was published in 1998, considerable advances have been made in the fields of pitch perception and speech perception. In addition, there have been major changes in the way that hearing aids work, and the features they offer.
Автор: Edmund Barton Название: Sensorineural Hearing Loss: Prevalence, Risk Factors and Treatment ISBN: 1536144754 ISBN-13(EAN): 9781536144758 Издательство: Nova Science Рейтинг: Цена: 103480.00 T Наличие на складе: Невозможна поставка. Описание: Hearing loss in the pediatric population is often a source of anxiety both for families and health professionals, with current rehabilitation options mainly consisting of hearing aids and cochlear implants. As such, the authors of Sensorineural Hearing Loss: Prevalence, Risk Factors and Treatment present an overview of the causes of progressive hearing loss (both congenital and acquired) and explore the management of this condition. Sensorineural hearing loss, if not properly treated, may likely compromise speech and, consequently, the psychosocial development of the affected child. Therefore, early diagnosis and treatment has a significant impact on the likelihood of hearing rehabilitation and on social development. The authors provide an analysis of the prevalence, stratification of risk factors, and the most appropriate treatment for sensorineural hearing loss. The authors go on to review the role of the gender medicine in the field of audiology. Currently, there is growing interest on the effects of gender differences on the pathophysiology and pharmacology of several disorders; however, there are still few data about the relation between gender-related factors and hearing loss. This compilation also proposes hyperbaric oxygenation as an adjunct therapy in the treatment of sudden sensorineural hearing loss. The authors take into consideration the physiologic, biochemical and cellular effect of oxygenation on the human brain and body. The authors discuss congenital cytomegalovirus infection, the most common cause of nonhereditary sensorineural hearing loss during childhood worldwide. It affects 0.2% to 2.5% of all live-born neonates and the highest incidence occurs in developing countries, where 1% to 5% of all live births can be infected. An overview of hearing loss caused by the Zika virus infection (both congenital and adult) is provided and recent discussion on the management of this condition is explored. First isolated in 1947, Zika virus rose to prominence after its outbreak in Latin America in 2015. Due to a high incidence of microcephaly in the Brazilian northeast, the correlation between Zika virus infection during pregnancy and this congenital malformation was recognized. With 30-35% of people suffering from presbycusis, also known as age-related hearing loss, it is the leading cause of hearing impairment among the elderly. Even though it is a multifactorial disease, its prevalence increases with aging and is higher among men. The authors propose that once age-related hearing loss has been diagnosed, the possibility of benefitting from conventional hearing aids should be taken into account according to hearing test results.
Автор: Francesco Dispenza, Francesco Martines Название: Sensorineural Hearing Loss: Pathophysiology, Diagnosis and Treatment ISBN: 1536150487 ISBN-13(EAN): 9781536150483 Издательство: Nova Science Рейтинг: Цена: 215410.00 T Наличие на складе: Невозможна поставка. Описание: Hearing loss is one the commonest disabling diseases affecting populations of all ages worldwide. The impairment of hearing may be the cause of impaired language development in children, the cause of scholarly issues in adolescents, the cause of worsening of quality of life in the adults, and the cause of isolation of aged people. In this book, the authors present the hearing loss in all its facets, starting from the basis of pathophysiology and anatomy, passing through the clinical and instrumental diagnosis and, finally, describing the most important diseases causing hearing loss with reasonable treatment options. A section was dedicated to the imaging of the ear with about 100 original figures. The readers will find a complete classification of genetic hearing loss and all information related to congenital deafness as well. A wide section was reserved to the description and discussion of the most important pathology leading to hearing loss (Menieres disease, otosclerosis, trauma and occupational hearing impairment, etc.). The treatment of hearing loss is continuously evolving with the progress of technology, and the authors gave a wide space to describe all treatment options available for the patients, providing all information useful to manage hearing disease correctly.
Автор: Saima Riazuddin, Zubair Ahmed Название: Inner Ear Development & Hearing Loss ISBN: 1624170110 ISBN-13(EAN): 9781624170119 Издательство: Nova Science Рейтинг: Цена: 224920.00 T Наличие на складе: Невозможна поставка. Описание: System science and engineering is a field that covers a wide spectrum of modern technology. A system can be seen as a collection of entities and their interrelationships, which forms a whole greater than the sum of the entities and interacts with people, organizations, cultures and activities and the interrelationships among them. Systems composed of autonomous subsystems are not new, but the increased complexity of modern technology demands ever more reliable, intelligent, robust and adaptable systems to meet evolving needs. This book presents papers delivered at the International Conference on System Science and Engineering ICSSE2015,
Название: Genetic Hearing Loss ISBN: 0367394928 ISBN-13(EAN): 9780367394929 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Genetic Hearing Loss branches into syndromic and nonsyndromic categorical directions in its coverage of the genetics behind hearing loss.
Автор: Williams Diana Название: Early Listening Skills for Children with a Hearing Loss ISBN: 0367193469 ISBN-13(EAN): 9780367193461 Издательство: Taylor&Francis Рейтинг: Цена: 45930.00 T Наличие на складе: Нет в наличии. Описание: Now in a revised second edition, Early Listening Skills is a practical manual for use with children and young people with underdeveloped listening skills related to hearing loss. The activities stimulate and develop auditory awareness and discrimination skills in children with a range of developmental levels and abilities.
Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2) ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
