Автор: Virella Gabriel Название: Medical Immunology 6ed ISBN: 0849396964 ISBN-13(EAN): 9780849396960 Издательство: Informa Цена: 63550 T Наличие на складе: Нет в наличии. Описание: With an abundance of illustrations, diagrams, and algorithms for a reader-friendly review of critical material, this Sixth Edition is fully updated and revised to clearly update and explore current diagnostic and clinical applications of immunology, as well as strategies for the modulation of immune response and the treatment of hypersensitivity, autoimmune response, and immune deficiency conditions. Organized into four sections that review clinical applications, methodological advances, immunological diseases, and cutting edge interventions, this guide leads readers through state-of-the-sciences technologies and demonstrates their implementation in day-to-day clinical practice.
Автор: Chu Название: Modern Immunohistochemistry with DVD-ROM ISBN: 1107040159 ISBN-13(EAN): 9781107040151 Издательство: Cambridge Academ Рейтинг: Цена: 334810.00 T Наличие на складе: Нет в наличии. Описание: Fully updated to reflect the latest developments in the field, this best-selling practical guide offers concise text, summary tables and high-quality images. An essential text for residents, this is also an extremely valuable resource for practitioners in anatomic pathology wishing to familiarise themselves with diagnostic markers at a quick glance.
Автор: Marc S. Ernstoff, Igor Puzanov, Caroline Robert, Adi M. Diab, Peter M. Hersey Название: SITC`s Guide to Immunotherapy Toxicity: Best Practices for Managing Side Effects of Cancer Treatment ISBN: 0826172148 ISBN-13(EAN): 9780826172143 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 45270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Part One contains chapter-based overviews of immune checkpoint inhibitors in the clinic. Part Two is structured by common and uncommon toxicities that affect major organ sites throughout the body.
Автор: Gerhard Gross Название: Stem Cell-dependent Therapies ISBN: 3110298260 ISBN-13(EAN): 9783110298260 Издательство: Walter de Gruyter Цена: 210690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Multipotent mesenchymal stem cells (MSCs) are a heterogeneous population of cells which reside in a variety of tissues. They differentiate into several mesodermal lineages, secrete a multitude of trophic factors and contribute to tissue homeostasis. MSCs are able to exert immunosuppressive activities by interfering with inflammatory cytokine production and with T- and B-cell proliferation. These immunomodulating properties make MSCs promising candidates for the treatment of chronic inflammatory and autoimmune disorders. There are, however, certain caveats involved including inappropriate migration of cells in the body, immune rejection, tumor formation, or graft versus host disease (GvHD). This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders and, lastly, tumors and solid organ transplantations. This book also questions the immunoprivileged status of MSCs, discusses the therapeutic role of MSCs in experimental animal disease models and their translation to the corresponding human disorders, envisions a role for MSCs in tumor interventions and, lastly, describes a systems biology approach for stem cells and inflammation.
Автор: Wang Jim Название: Medical Immunology ISBN: 1632413914 ISBN-13(EAN): 9781632413918 Издательство: Неизвестно Цена: 160930.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Gerhard Gross, Thomas Haupl Название: Stem Cell-Dependent Therapies: Mesenchymal Stem Cells in Chronic Inflammatory Disorders ISBN: 3110298317 ISBN-13(EAN): 9783110298314 Издательство: Walter de Gruyter Цена: 283890.00 T Наличие на складе: Невозможна поставка. Описание: This book investigates the current state of the MSC-dependent therapy of chronic inflammatory disorders and autoimmune diseases. Among the covered topics are GvHD, chronic kidney, liver and lung disease, ischemic heart and inflammatory bowel disease, diabetes, osteoarthritis, various rheumatic and neurological disorders, tumors and solid organ transplantations.
Автор: Apurba Sankar Sastry, Bhat Sandhya K Название: Review of Microbiology and Immunology ISBN: 9386322390 ISBN-13(EAN): 9789386322395 Издательство: JayPee Brothers Рейтинг: Цена: 27450.00 T Наличие на складе: Невозможна поставка.
Автор: Apurba Sankar Sastry, K Sandhya Bhat Название: Review of Microbiology and Immunology ISBN: 935270410X ISBN-13(EAN): 9789352704101 Издательство: JayPee Brothers Рейтинг: Цена: 32730.00 T Наличие на складе: Невозможна поставка. Описание: Considers lethal autonomous weapon systems, approaching the issue from five different perspectives. The United Nations Office for Disarmament Affairs Occasional Papers are a series of ad hoc publications featuring papers or statements made at meetings, symposiums, seminars, workshops or lectures that deal with topical issues in the field of arms limitation, disarmament and international security.
Автор: Subhash C. Basak, Apurba K. Bhattacharjee, Ashesh Nandy Название: Zika Virus: Basic Biology, Symptoms, Transmission, Immunology, and Anti-Zika Drug Discovery ISBN: 1536149705 ISBN-13(EAN): 9781536149708 Издательство: Nova Science Рейтинг: Цена: 77080.00 T Наличие на складе: Невозможна поставка. Описание: The bubonic plague, smallpox, HIV/AIDS, malaria, and influenza are some of the worst epidemics/pandemics that afflicted human beings from antiquity to modern times, killing millions of people. The mosquito-borne human-infecting viruses, rotavirus, and the seasonal influenza regularly affect lives across continents in the millions. Currently, we are facing various disease-inducing organisms of the Flavivirus family the Yellow fever virus (YFV), West Nile virus (WNV), Japanese encephalitis virus (JEV), Tick-borne encephalitis virus (TBEV), Dengue virus (DENV) and Zika virus (ZIKV). Zika virus was first isolated from a febrile rhesus monkey in the Zika forest of Uganda in 1947. It drew out heightened attention following the large number of microcephaly in newborn babies in Latin America in 2015. On 1 February 2016, WHO declared that the association of Zika infection with clusters of microcephaly and other neurological disorders constituted a Public Health Emergency of International Concern. Although the severity and number of ZIKV afflicted cases have gone down lately, the public health community worldwide is keeping a watchful eye on it. ZIKV is an enveloped virus with a positive-sense RNA genome that translates into a single polypeptide, which then gets cleaved into three structural and seven nonstructural viral proteins. As compared to the earlier centuries, we have an expanding repertoire of diverse and fast acting technologies available at our hand to manage and mitigate emerging diseases. Completion of the Human Genome Project has given rise to sequencing methods which can quickly determine the genetic sequence of an alarming pathogen. Following Moores law, the power of computers, essential for data analysis and visualization, has grown substantially with time. The combination of genomic data of pathogens, computational modeling methods, and data driven methodologies can lead to a generic approach of surveillance, mitigation, vaccine design as well as new drug discovery for emerging pathogens. The four pillars of this may consist of: a) Epidemiological approaches for the characterization of carriers of next possible emerging pathogens; b) Fast computational sequence comparison methods for the characterization of emerging pathogens to understand how novel or severe they could be; c) Once the sequences of the pathogen have been determined, computer-aided vaccine design (CAVD) methods can be used to suggest a set of probable vaccine candidates for quick synthesis and testing in the laboratory; and d) Computer-assisted design of novel therapeutics and their laboratory testing as well as repurposing of already existing FDA-approved drugs. A combination of different classes of methods in vivo, in vitro and in silico will be needed to tackle suddenly emerging viruses like the Zika virus. As in many other fields of biomedical research, high throughput and low cost in silico technologies may provide the first line of defense against such emerging pathogens providing decision support systems for the judicious applications of medium throughput in vitro methods and low throughput as well as costly in vivo techniques. An emerging trend in many scientific disciplines is a strong tendency of being transformed into some form of information science. The editors of this book sincerely hope that the four-pronged computer-assisted approach described in this book will help in managing and mitigating emerging infectious diseases like Zika.
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