Название: Jumbo book of hidden pictures (r) ISBN: 1629798266 ISBN-13(EAN): 9781629798264 Издательство: Random House (USA) Рейтинг: Цена: 7970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This jumbo book is packed with more than 175 favourite Hidden Pictures puzzles drawn in the classic Highlights black-and-white style. With more than 15,000 things to find, this is an ideal gift for all ages.
Автор: Smith, Kim Название: E.t. the extra-terrestrial ISBN: 1683690265 ISBN-13(EAN): 9781683690269 Издательство: Random House (USA) Рейтинг: Цена: 4900.00 T Наличие на складе: Невозможна поставка. Описание: Arriving just in time for the 35th anniversary of the film, this picture book adaptation will introduce everyone s favorite alien to a new generation of fans!
Автор: Martini, Frederic H. Nath, Judi L. Bartholomew, Ed Название: Fundamentals of anatomy & physiology, global edition 11 ISBN: 1292229861 ISBN-13(EAN): 9781292229867 Издательство: Pearson Education Рейтинг: Цена: 107170.00 T Наличие на складе: Невозможна поставка. Описание: This reader is accompanied with a CD that contains the full audio of the text in MP3 format. Oliver`s mother dies when he is born and he is brought up in a workhouse. His first years are cold and lonely - and then he runs away to London. But he falls into the hands of Fagin and the terrifying Bill Sykes. They try to turn Oliver into a criminal. Will he escape to find a better life?
Название: Concrete Mixtures & Reports of Tests.. ISBN: 1360804781 ISBN-13(EAN): 9781360804781 Издательство: Неизвестно Цена: 21140.00 T Наличие на складе: Невозможна поставка.
Автор: Vladimir A. Sirotkin Название: Preferential Solvation and Hydration of Proteins in Water-Organic Mixtures: Two Sides of One Coin ISBN: 1536160202 ISBN-13(EAN): 9781536160208 Издательство: Nova Science Рейтинг: Цена: 89750.00 T Наличие на складе: Невозможна поставка. Описание: This book describes the basic principles of a novel methodology to investigate the preferential hydration and solvation of proteins in ternary protein-water-organic solvent systems. Protein-water interactions are well-known to play a critical role in determining the function, structure, and stability of protein macromolecules. Elucidation of the processes occurring upon protein hydration in the presence of third component (organic solvents, salts, urea) is essential in a wide range of biophysical, biomedical, and biotechnological applications. In particular, there are many advantages in employing water-poor organic solvents, including the suppression of undesirable side reactions caused by water, the biocatalysis of reversed hydrolytic reactions (transesterification, peptide synthesis), or increased thermostability. Distinct intermediate protein states induced by organic solvents may be responsible for numerous neurodegenerative diseases (Alzheimers disease, Parkinsons disease, and Huntingtons disease). However, the manner in which organic solvents increase/decrease the thermal stability, induce/reduce the extent of denaturation, and stabilise/destabilise the partially folded conformations of proteins (amyloid fibrils and molten globules) is an intricate function of water content in organic liquids. Preferential hydration/solvation is an effective method for revealing the mechanism of the protein stabilisation or denaturation. When a protein interacts with a binary water-organic solvent mixture, the three components do not equally mix. Water or organic solvent molecules exist preferentially in the proteins solvation shell. This difference between the solvation shell and bulk solvent in the solvent components has been termed preferential solvation. Preferential solvation is a thermodynamic quantity that describes the protein surface occupancy by the water and cosolvent molecules. This is associated with the actual numbers of water/cosolvent molecules that are in contact with the proteins surface. It was also found that the protein destabilisation is directly associated with the preferential binding of the denaturant molecules to specific protein groups. The aim of our study is to monitor the preferential solvation and preferential hydration of the protein macromolecules at low, intermediate, and high water content in organic solvents at 25 oC. Our approach is based on the simultaneous measurements of the absolute values of the water and organic solvent sorption. The preferential solvation/hydration parameters were calculated using the water and organic solvent sorption values. The preferential solvation/hydration parameters were compared with the corresponding changes in the protein structure that transpire regarding the interaction of the protein with organic solvent and water molecules. The effect of organic solvent on the protein structure was investigated by FTIR (Fourier Transform Infrared) spectroscopy.
Автор: Danielson Phillip B. Название: Mitochondrial DNA Analysis by Denaturing Liquid Chromatography for the Separation of Mixtures in Forensic Samples - Scholar`s Choice Edition ISBN: 1296046907 ISBN-13(EAN): 9781296046903 Издательство: Неизвестно Рейтинг: Цена: 24210.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.
This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.
As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
