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Radiopharmaceutical chemistry, 


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Название:  Radiopharmaceutical chemistry
ISBN: 9783319989464
Издательство: Springer
Классификация:
ISBN-10: 3319989464
Обложка/Формат: Hardcover
Страницы: 651
Вес: 2.60 кг.
Дата издания: 13.05.2019
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 336 tables, color; 336 illustrations, color; 152 illustrations, black and white; approx. 575 p. 488 illus., 336 illus. in color.
Размер: 222 x 287 x 31
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic.

The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like The Production of Radionuclides and Basics of Radiochemistry. The second section is the main focus of the book. In this section, each chapters author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a Best of the Rest chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including Bioconjugation Methods, Click Chemistry in Radiochemistry, and Radiochemical Instrumentation.

This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.



Biological Models in Radiopharmaceutical Development

Автор: R.M. Lambrecht
Название: Biological Models in Radiopharmaceutical Development
ISBN: 9401065586 ISBN-13(EAN): 9789401065580
Издательство: Springer
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Цена: 81050.00 T
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Описание: Radiophannaceuticals labeled with short-lived radionuclides are utilized to unravel biochemical processes, and to diagnosis and treat diseases of the living body are-developed through extensive evaluation in ~iological models.

Radiopharmaceuticals for therapy

Автор: Knapp, F. F. Dash, Ashutosh
Название: Radiopharmaceuticals for therapy
ISBN: 8132226062 ISBN-13(EAN): 9788132226062
Издательство: Springer
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Цена: 121110.00 T
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Описание: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation.  Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy.  In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.

New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

Автор: Ali M. Emran
Название: New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control
ISBN: 1489906282 ISBN-13(EAN): 9781489906281
Издательство: Springer
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Цена: 186330.00 T
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Описание: Proceedings of an American Chemical Society international symposium, held in Washington, DC, August 27-30, 1990

Название: Therapeutic Radiopharmaceuticals Labelled with Copper-67, Rhenium-186 and Scandium-47
ISBN: 9201272227 ISBN-13(EAN): 9789201272225
Издательство: Mare Nostrum (Eurospan)
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Цена: 16630.00 T
Наличие на складе: Нет в наличии.
Описание: Presents the outcome of an IAEA coordinated research project (CRP) focusing on the production quality control and radiopharmaceutical aspects of three key radionuclides - 67CU 186Re and 47Sc - which have been selected based on their theranostic potential and their dual production routes.

Trends in Radiopharmaceuticals (ISTR-2019): Proceedings of an International Symposium Held in Vienna, Austria, 28 October–1 November 2019

Название: Trends in Radiopharmaceuticals (ISTR-2019): Proceedings of an International Symposium Held in Vienna, Austria, 28 October–1 November 2019
ISBN: 9201177208 ISBN-13(EAN): 9789201177209
Издательство: Mare Nostrum (Eurospan)
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Цена: 30930.00 T
Наличие на складе: Невозможна поставка.
Описание: The use of radiopharmaceuticals is an important tool not only for management of diseases and dysfunctions, but also for better understanding human diseases and developing effective treatment options, such as in the case of neurology. In this context, there is concern of continuous, impressive progress in nuclear medicine which is linked to the development of new radiopharmaceuticals and efficient production of relevant radioisotopes. These proceedings highlight the main findings and developments discussed during the International Symposium on Trends in Radiopharmaceuticals. They cover the key issues and advances in the field of radiopharmaceuticals from development, production, and use of diagnostic, therapeutic, and theranostic radioisotopes and radiopharmaceuticals, as well as regulatory and licensing issues related to their production. Additional topics addressed were education, certification and training methodologies. A supplementary file contains the detailed programme of the symposium and the abstracts of all oral and poster presentations.

Radiopharmaceuticals

Автор: Calabria
Название: Radiopharmaceuticals
ISBN: 303027778X ISBN-13(EAN): 9783030277789
Издательство: Springer
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Цена: 79190.00 T
Наличие на складе: Поставка под заказ.

Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects

Автор: G. St?cklin; V.W. Pike
Название: Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects
ISBN: 9048142857 ISBN-13(EAN): 9789048142859
Издательство: Springer
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Цена: 186340.00 T
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Описание: Radiochemical methodology constitutes the most important base for the successful functioning of a PET group in the routine production and development of radiopharmaceuticals.

Production, Quality Control and Clinical Applications of Radiosynovectomy Agents

Название: Production, Quality Control and Clinical Applications of Radiosynovectomy Agents
ISBN: 9201185200 ISBN-13(EAN): 9789201185204
Издательство: Mare Nostrum (Eurospan)
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Цена: 38810.00 T
Наличие на складе: Нет в наличии.
Описание: Presents recommendations and suggestions for production, quality control and quality assurance procedures for Member State laboratories in charge of radiopharmaceutical production, with a focus on the latest radiation synovectomy agents.

Radiopharmaceuticals

Автор: Ferdinando Calabria; Orazio Schillaci
Название: Radiopharmaceuticals
ISBN: 303027781X ISBN-13(EAN): 9783030277819
Издательство: Springer
Рейтинг:
Цена: 79190.00 T
Наличие на складе: Поставка под заказ.

Alternative Radionuclide Production with a Cyclotron

Название: Alternative Radionuclide Production with a Cyclotron
ISBN: 9201030215 ISBN-13(EAN): 9789201030214
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 38450.00 T
Наличие на складе: Нет в наличии.
Описание: Cyclotrons are currently used for the preparation of a wide variety of radionuclides that have applications in single photon emission computed tomography (SPECT) and positron emission tomography (PET). Consequently, there is high demand from IAEA Member States for support in the area of radiopharmaceutical production using cyclotron produced radioisotopes. This publication describes the potential radionuclide production routes using cyclotrons in different energy ranges and provides methods for the development of targets and provides details of the chemistry for the separation of radionuclides from target materials. The readership of this publication includes scientists, operators interested in putting this technology into practice, technologists already working with cyclotrons who wish to enhance the utility of existing machines, and managers in the process of setting up radionuclide facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.

Safety and efficacy of radiopharmaceuticals 1987

Автор: Knud Kristensen; Elisabeth N?rbygaard
Название: Safety and efficacy of radiopharmaceuticals 1987
ISBN: 940108016X ISBN-13(EAN): 9789401080163
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Safety and Efficacy of Radiopharmaceuticals was established as a very important and comprehensive subject at the First Europe- an Symposium on Radiopharmacy and Radiopharmaceuticals in Denmark in 1983.

Radiopharmaceuticals in the Management of Leptomeningeal Metastasis

Автор: Wong
Название: Radiopharmaceuticals in the Management of Leptomeningeal Metastasis
ISBN: 303114290X ISBN-13(EAN): 9783031142901
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Поставка под заказ.
Описание: This book reviews the current clinical practice of leptomeningeal metastasis (LM) diagnosis and treatment, which is predominately by intrathecal chemotherapy and/or in combination with external beam radiotherapy. LM is a refractory lethal complication of many human malignancies when neoplastic cells grow in the meninges. The use of penetrating emissions from radionuclides has the advantages of visualizing cerebrospinal fluid (CSF) flow and ablating meninges at shallow depths and has been used to diagnose CSF flow anomalies and to treat LM. The scientific bases of using radionuclides inside human CSF and ablating LM will be discussed within the text, with results from established and completed clinical trials to explore optimal use of radionuclides to diagnose and treat LM. Many limitations of current practices of treating LM are also discussed, as well as potential avenues of overcoming these limitations. This book is an ideal guide for clinical researchers in the practice of treating leptomeningeal metastasis including radiologists, neurologists, oncologists and radiotherapists as well as their associates.


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