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Hepatic stem cells, 


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Название:  Hepatic stem cells
ISBN: 9781493989607
Издательство: Springer
Классификация:




ISBN-10: 149398960X
Обложка/Формат: Hardcover
Страницы: 248
Вес: 0.67 кг.
Дата издания: 08.12.2018
Серия: Methods in molecular biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 60 illustrations, color; 11 illustrations, black and white; viii, 256 p. 71 illus., 60 illus. in color.
Размер: 184 x 260 x 23
Читательская аудитория: Professional & vocational
Подзаголовок: Methods and protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume looks at the liver’s epithelial cells—hepatocytes and cholangiocytes—and their progenitors. This book is divided into five parts: isolation of progenitor cells; characterization of liver progenitors in vivo; generation of hepatocytes, cholangiocytes, and their progenitors; reconstitution of liver tissue structures; and liver injury models. The chapters in this book cover topics such as expansion of bipotential liver stem/progenitor cells (LPCs) from fetal and neonatal liver; identifying progenitor cells involved in liver regeneration in vivo; methods for generating hepatocytes and cholangiocytes from multiple cellular sources; 3D tissue structures ex vivo; and resolving hepatic fibrosis by bone marrow transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, Hepatic Stem Cells: Methods and Protocols is a valuable resource to help researchers understand the current theories used to study hepatic stem/progenitor cells, and aid them in performing experiments related to liver biology and pathophysiology.

Дополнительное описание: Long-Term Culture of Mouse Fetal Hepatic Stem/Progenitor Cells.- Isolation of Bipotential Liver Progenitor Cells from Neonatal Mouse Liver.- Identification and Isolation of Clonogenic Cholangiocyte in Mouse.- Isolation and Expansion of Rat Hepatocytic Pro


Hepatic Transport of Organic Substances

Автор: Ernst Petzinger; Rolf K.H. Kinne; Helmut Sies
Название: Hepatic Transport of Organic Substances
ISBN: 3642742491 ISBN-13(EAN): 9783642742491
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of a Symposium, held May 8-11, 1988 at Schloss Ringberg, Rottach Egern

Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy

Автор: Vicente Felipo
Название: Advances in Cirrhosis, Hyperammonemia, and Hepatic Encephalopathy
ISBN: 1461377242 ISBN-13(EAN): 9781461377245
Издательство: Springer
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Цена: 46570.00 T
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Описание: Proceedings of an international symposiu, held in Valencia, Spain, December 2-4, 1996

Liver Diseases and Hepatic Sinusoidal Cells

Автор: Kyuichi Tanikawa; Takato Ueno
Название: Liver Diseases and Hepatic Sinusoidal Cells
ISBN: 4431680128 ISBN-13(EAN): 9784431680123
Издательство: Springer
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Цена: 46570.00 T
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Описание: Hepatic sinusoidal cells such as sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and pit cells play an important role in hemodynamic and metabolic function and are involved in various liver diseases.

Liver Diseases and Hepatic Sinusoidal Cells

Автор: Kyuichi Tanikawa; Takato Ueno
Название: Liver Diseases and Hepatic Sinusoidal Cells
ISBN: 4431702377 ISBN-13(EAN): 9784431702375
Издательство: Springer
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Цена: 81050.00 T
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Описание: Hepatic sinusoidal cells such as sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and pit cells play an important role in hemodynamic and metabolic function and are involved in various liver diseases.

Hepatic Metabolism and Disposition of Endo- and Xenobiotics

Автор: Karl-Walter Bock; W. Gerok; S. Matern
Название: Hepatic Metabolism and Disposition of Endo- and Xenobiotics
ISBN: 0792389530 ISBN-13(EAN): 9780792389538
Издательство: Springer
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Цена: 277650.00 T
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Hepatic Surgery: Recent Advances

Автор: Cerny Lewis
Название: Hepatic Surgery: Recent Advances
ISBN: 1632416344 ISBN-13(EAN): 9781632416346
Издательство: Неизвестно
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Цена: 150200.00 T
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Regulation of Hepatic Metabolism

Автор: K. Jungermann; F.C. Kauffman; R.G. Thurman
Название: Regulation of Hepatic Metabolism
ISBN: 1468450433 ISBN-13(EAN): 9781468450439
Издательство: Springer
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Цена: 93160.00 T
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Описание: The liver contains many cell types including hepatic parachymal cells, Kiipffer cells, Ito cells, and endothelial cells. The most abundant cell type, the parenchymal cells, are biochemically and structurally heterogeneous.

Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity

Автор: Santiago Grisol?a; Vicente Felipo; Maria-Dolores M
Название: Cirrhosis, Hepatic Encephalopathy, and Ammonium Toxicity
ISBN: 1468458280 ISBN-13(EAN): 9781468458282
Издательство: Springer
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Цена: 93160.00 T
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Описание: Proceedings of an international symposium held in Valencia, Spain, November 27--29, 1989

Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity

Автор: Vicente Felipo; Santiago Grisol?a
Название: Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity
ISBN: 1461358205 ISBN-13(EAN): 9781461358206
Издательство: Springer
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Цена: 46570.00 T
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Описание: This volume contains the papers presented at the International Symposium on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy", held in Valencia, Spain, January 24th-27th, 1994.

Hepatic Steatosis: Clinical Risk Factors, Molecular Mechanisms and Treatment Outcomes

Автор: Sergio Santos
Название: Hepatic Steatosis: Clinical Risk Factors, Molecular Mechanisms and Treatment Outcomes
ISBN: 1633214036 ISBN-13(EAN): 9781633214033
Издательство: Nova Science
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Цена: 234420.00 T
Наличие на складе: Невозможна поставка.
Описание: In the last few years, human metabolic disorders have become some of the most prevalent and prejudicial diseases worldwide. Hepatic steatosis, among many health problems, has several risk factors related to the disease prognosis such as obesity, nutritional problems, diabetes, hypertension, hyperuricemia, and even sleep apnea. Alcohol abuse also can lead to a severe liver-steatosis state. The progression of hepatic steatosis can lead to complications such as cryptogenic cirrhosis and hepatocellular carcinoma. Drug therapy has instead been focused on the mitigation of risk factors, however new potential therapeutic perspectives are being discussed. This book presents the origins, diagnosis and epidemiology of hepatic steatosis with new perceptions. The authors also aimed to show the molecular basis and signaling involved in liver disorders, discussing the inflammatory process, lipid metabolism and angiogenesis mechanisms. The role of nutrition in the treatment and development of steatosis was also presented and new advances were highlighted. Recent studies revealed the need for the use of bariatric surgery, functional foods and the modulation of endogenous systems, such as the sirtuins and renin-angiotensin systems, to treat liver disease. In this context, we aimed to introduce, review and discusses one of the most widespread metabolic disorders in the world: hepatic steatosis and its repercussions.

Hepatic Encephalopathy and Nitrogen Metabolism

Автор: D. H?ussinger; G. Kirchels; F. Schless
Название: Hepatic Encephalopathy and Nitrogen Metabolism
ISBN: 9400788576 ISBN-13(EAN): 9789400788572
Издательство: Springer
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Цена: 250630.00 T
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Описание: Hepatic Encephalopathy and Nitrogen Metabolism is an interdisciplinary symposium bringing together basic science and clinical applications. It contains up-to-date research findings at the highest scientific level.

Hepatic Encephalopathy

Автор: Roger F. Butterworth; Gilles Pomier Layrargues
Название: Hepatic Encephalopathy
ISBN: 1461288517 ISBN-13(EAN): 9781461288510
Издательство: Springer
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Цена: 144410.00 T
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Описание: Hepatic Encephalopathy (HE) is a neuropsychiatric disorder resul t- ing from liver failure. HE may be associated with fulminant (acute) hepatic failure or chronic liver disease with portal-systemic shunting. The latter condition is characterized neuropathologically by astro- cytic rather than neuronal changes (Alzheimer Type II astrocytosis). The former is frequently accompanied by cerebral edema. Several hypotheses have been proposed to explain the pathogene- sis of HE. These include: 1. A toxic action of a substance (or substances) such as ammonia on brain function 2. A deficit of cerebral energy metabolism 3. Neurotransmitter changes, and, more recently 4. The role of "endogenous benzodiazepines. " This volume summarizes the results of a symposium held in Val David, Quebec from October 3D-November I, 1988, that was devoted to an evaluation of the evidence for and against the various hypothe- ses of HE. Data from studies in patients, in experimental (animal) models of HE, and in cultured cell preparations were discussed. In addition, a review of available approaches to the treatment and man- agement of HE was included. The therapeutic use of lactulose, anti- biotics, dietary treatment, and branched-chain amino acid treatments were included, as well as the results of preliminary studies of the therapeutic use of the benzodiazepine antagonist, flumazenil. Roger F. Butterworth, PhD Gilles Pomier Layrargues, MD v Acknowledgments The symposium was made possible by the generous financial assistance of: Hoffman-La Roche Ltd.


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