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Stress and the Developing Brain, Lisa Wright, Tara Perrot


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Автор: Lisa Wright, Tara Perrot
Название:  Stress and the Developing Brain
ISBN: 9781615045273
Издательство: Mare Nostrum (Eurospan)
Классификация:

ISBN-10: 1615045279
Обложка/Формат: Paperback
Страницы: 76
Вес: 0.14 кг.
Дата издания: 30.12.2012
Серия: Colloquium series on the developing brain
Язык: English
Иллюстрации: Illustrations, black and white
Размер: 235 x 191 x 4
Читательская аудитория: General (us: trade)
Ключевые слова: Neurology & clinical neurophysiology
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Поставляется из: Англии
Описание: The human brain does not develop in a vacuum according to a set of predetermined blueprints--it is involved in a dynamic interplay with the environment that influences gene expression and ultimately structure and function. Some cortical regions, such as the prefrontal cortex (PFC) undergo structural changes throughout the adolescent period and into early adulthood, making their structure and functions particularly interesting to study with respect to gene-environment interactions. Repeated exposure to stress is a predisposing factor in the emergence of various mental illnesses, such as anxiety and depression, although this is by no means an absolute relationship. While some people appear to be vulnerable to the effects of repeated stressors, others are resilient, and this individual variability is partly due to developmental programming of brain regions involved in modulating stress responding, such as the PFC. In the present book, we will discuss features of adolescent brain development that may provide a basis for neural plasticity in stress responding: the highly protracted development of the PFC, the profound change in interconnectedness among cortical and subcortical brain regions, and the characteristic rise and fall pattern for many of the late-developing aspects of neural architecture in PFC and other stress-related brain regions.

Neuroscience: exploring the brain. 4 ed.

Автор: Bear M.
Название: Neuroscience: exploring the brain. 4 ed.
ISBN: 1451109547 ISBN-13(EAN): 9781451109542
Издательство: Jones & Bartlett
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Цена: 56750.00 T
Наличие на складе: Невозможна поставка.
Описание: Acclaimed for its clear, friendly style, excellent illustrations, leading author team, and compelling theme of exploration, Neuroscience: Exploring the Brain, 4e takes a fresh, contemporary approach to the study of neuroscience, emphasizing the biological basis of behavior. The authors’ passion for the dynamic field of neuroscience is evident on every page, engaging students and helping them master the material.   In just a few years, the field of neuroscience has been transformed by exciting new technologies and an explosion of knowledge about the brain.  The human genome has been sequenced, sophisticated new methods have been developed for genetic engineering, and new methods have been introduced to enable visualization and stimulation of specific types of nerve cells and connections in the brain.  The new Fourth Edition has been fully updated to reflect these and other rapid advances in the field, while honoring its commitment to be student-friendly with striking new illustrations, additional animations, and an unparalleled array of online resources.

The Developing Human Brain: Growth and Adversities

Автор: Gilles
Название: The Developing Human Brain: Growth and Adversities
ISBN: 1908316411 ISBN-13(EAN): 9781908316417
Издательство: Wiley
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Цена: 137280.00 T
Наличие на складе: Поставка под заказ.
Описание: Clinics in Developmental Medicine Well over 200 illustrations, many in colour Co-authored by two experts in neuropathology and neuroimaging Takes a quantitative approach to brain growth in weight, gyrus formation, myelination, and spectroscopy of the developing brain.

Calcium-Binding Proteins in the Human Developing Brain

Автор: N. Ulfig
Название: Calcium-Binding Proteins in the Human Developing Brain
ISBN: 3540434631 ISBN-13(EAN): 9783540434634
Издательство: Springer
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Цена: 93160.00 T
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Описание: In the mature brain calcium ions play pivotal roles in transmembrane and intracellular transmission of signals. Thus, calcium is involved in numerous neuronal functions, and this text explores the complex processes dependent on and modulated by calcium.

Guidance Cues in the Developing Brain

Автор: Ivica Kostovic
Название: Guidance Cues in the Developing Brain
ISBN: 364262426X ISBN-13(EAN): 9783642624261
Издательство: Springer
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Цена: 93160.00 T
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Описание: Molecules serving as guidance cues for migratory cells, growing axons and for recognition of postsynaptic targets are a major topic for research because they are directly involved in the formation of neuronal circuits, thus creating the foundation for subsequent functional refinement through interactions with the environment.

Sex and the Developing Brain: Second Edition

Автор: McCarthy Margaret M.
Название: Sex and the Developing Brain: Second Edition
ISBN: 161504728X ISBN-13(EAN): 9781615047284
Издательство: Mare Nostrum (Eurospan)
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Цена: 51750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain, and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone which gains access to the brain and is further metabolized into active androgens and estrogens which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. Epigenetic modifications to the genome both establish and maintain sex differences in the brain and behavior. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health. Boys are much more likely to be diagnosed with autism spectrum or attention and hyperactivity disorders, as well as speech and language deficits, compared to girls. By contrast, women are more likely to suffer from affective disorders, such as depression, anxiety, compulsion, and eating disorders and more likely to experience autoimmune and neurodegenerative disorders. Schizophrenia with an early onset is more common in males but a late-onset version is markedly more frequent in females. Male biased disorders have origins in development while female biased disorders are almost exclusively post-puberty. This remarkable shift in disease risk demands our attention. Novel insights into the biological origins of disease are also gained by comparing and contrasting the same processes in different sexes.

Sex and the Developing Brain

Автор: Margaret M. McCarthy
Название: Sex and the Developing Brain
ISBN: 1615047697 ISBN-13(EAN): 9781615047697
Издательство: Mare Nostrum (Eurospan)
Цена: 58480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain, and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone which gains access to the brain and is further metabolized into active androgens and estrogens which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. Epigenetic modifications to the genome both establish and maintain sex differences in the brain and behavior. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health. Boys are much more likely to be diagnosed with autism spectrum or attention and hyperactivity disorders, as well as speech and language deficits, compared to girls. By contrast, women are more likely to suffer from affective disorders, such as depression, anxiety, compulsion, and eating disorders and more likely to experience autoimmune and neurodegenerative disorders. Schizophrenia with an early onset is more common in males but a late-onset version is markedly more frequent in females. Male biased disorders have origins in development while female biased disorders are almost exclusively post-puberty. This remarkable shift in disease risk demands our attention. Novel insights into the biological origins of disease are also gained by comparing and contrasting the same processes in different sexes.

Endocrine Disruptors and The Developing Brain

Автор: Andrea C. Gore, Sarah M. Dickerson
Название: Endocrine Disruptors and The Developing Brain
ISBN: 1615040870 ISBN-13(EAN): 9781615040872
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 41580.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Addresses the evidence for endocrine disrupting chemical (EDC) action on the developing brain. Topics covered include background about EDCs, evidence for exposures, concerns about EDC effects in the developing organism, and particularly on the developing nervous system, how EDCs perturb the brain`s neuroendocrine systems, and transgenerational epigenetic effects of EDCs.


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