Автор: Mieczyslaw Pokorski Название: Lung Cancer and Autoimmune Disorders ISBN: 3319384902 ISBN-13(EAN): 9783319384900 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Lung cancer and autoimmune diseases are complex entities in that they involve gene disturbance, gene polymorphism, and impaired gene repair mechanisms. The volume focuses on altered gene expression in tumor processes and in chronic autoimmune disorders.
Автор: Domenico Coppola Название: Molecular Pathology and Diagnostics of Cancer ISBN: 9402402098 ISBN-13(EAN): 9789402402094 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses.
Автор: Yuti Chernajovsky; Paul D. Robbins Название: Gene Therapy for Autoimmune and Inflammatory Diseases ISBN: 3034803060 ISBN-13(EAN): 9783034803069 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This text addresses the latest advances in viral and non-viral vectors as well as novel targets and methods for the treatment of autoimmune and inflammatory disease. Its main focus is on pre-clinical testing with up-to-date clinical trials.
Автор: Jorge R. Oksenberg; David Brassat Название: Immunogenetics of Autoimmune Disease ISBN: 1489997482 ISBN-13(EAN): 9781489997487 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches.
Автор: Andrew G. Demaine; J.-Paul Banga; Alan M. McGregor Название: The Molecular Biology of Autoimmune Disease ISBN: 3642751350 ISBN-13(EAN): 9783642751356 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the NATO Advanced Research Workshop on Molecular Biology and Autoimmune Disease held in Athens, Greece, from April 16-20, 1989
Автор: W. Edward Highsmith, Jr. Название: Molecular Diagnostics ISBN: 1493942654 ISBN-13(EAN): 9781493942657 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients. Presented as a standard outline, each chapter focuses on a specific molecular test and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question. Authored by renowned experts in the field, Molecular Diagnostics: 12 Tests That Changed Everything is a valuable resource for pathologists, pathology residents, laboratory directors, development personnel, lab medicine fellows and those working in the broad area of oncology, infectious disease and genetics.
Автор: Erika Pestana; Sandor Belak; Adama Diallo; John R. Название: Early, rapid and sensitive veterinary molecular diagnostics - real time PCR applications ISBN: 9400797311 ISBN-13(EAN): 9789400797314 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This text is a comprehensive account of the practical aspects of Real time PCR and its application to veterinary diagnostic laboratories. It covers theoretical aspects of PCR as well as quality control features necessary to maintain an assured testing system.
Автор: Mousumi Debnath; Godavarthi B.K.S. Prasad; Prakash Название: Molecular Diagnostics: Promises and Possibilities ISBN: 9400791194 ISBN-13(EAN): 9789400791190 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques, instrumentation, applications and market of molecular diagnostics. It also includes advanced molecular diagnostic techniques.
Автор: Tomasz Jadczyk; Ewa Bryndza Tfaily; Sachin Mishra; Название: Innovative Diagnostics and Treatment: Nanorobotics and Stem Cells ISBN: 9811045267 ISBN-13(EAN): 9789811045264 Издательство: Springer Рейтинг: Цена: 51230.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: 1. Introduction 1.1 Current strategies for cancer and cardiovascular disease diagnosis and treatment 1.2 Therapeutic agents in the treatment of cardiovascular diseases (extensive list including drug name, its application, current limitations) 1.3 Therapeutic agents in the treatment of cancer (extensive list including drug name, its application, current limitations) 1.4 Imaging agents for diagnosis of cardiovascular diseases (extensive list) 1.5 Imaging agents for diagnosis of cancer (extensive list) 2. Integrated therapeutic-diagnostic systems for cancer and cardiovascular diseases 3. Nanorobotic agents 3.1 Types of nanorobots 3.2 Energy sources 3.3 Manipulation and control techniques 3.4 In vivo guidance and navigation of nano/micro carriers 4. Application of nanorobots for nanotheranostics 4.1 Nanorobots as a therapeutic platform 4.2 Nanorobots as a diagnostic platform 4.3 Multifunctional navigable nano/micro devices 4.4 In vivo perspective application in cancer and cardiovascular diseases
Автор: Volker A. Erdmann; Stefan Jurga; Jan Barciszewski Название: RNA and DNA Diagnostics ISBN: 3319173049 ISBN-13(EAN): 9783319173047 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”
Автор: Harald H. Kessler Название: Molecular Diagnostics of Infectious Diseases ISBN: 3110327880 ISBN-13(EAN): 9783110327885 Издательство: Walter de Gruyter Рейтинг: Цена: 117710.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The prevalence of infectious diseases is worldwide increasing. Therefore, detection methods for infectious pathogens change quickly. In the 3rd edition of Kessler´s Molecular Diagnostics of Infectious Diseases laboratory professionalists get valueable information about the current diagnostic methods, tipps and tricks in terms of sample processing, quality control, and interpretation of the results. For clinicians the book is a valuable aid for decision-making in ordering appropriate tests as well as in assuring the necessary quality of the sample material.
Автор: Coppola Название: Molecular Pathology and Diagnostics of Cancer ISBN: 9400771916 ISBN-13(EAN): 9789400771918 Издательство: Springer Рейтинг: Цена: 200260.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Molecular pathology is based on the emergence of new techniques that greatly enhance the diagnostic accuracy when facing with challenging differential diagnoses.
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