Letters Upon the Atalantis of Plato, and the Ancient History of Asia: Intended as a Continuation of the Letters Upon the Origin of the Sciences Addres, Bailly Jean Sylvain, Jacque James

Автор: Michael Bishop
Название: Earth and Mind: Dreaming, Writing, Being: Nine Contemporary French Poets - Yves Bonnefoy, Jacqueline Risset, Salah Stetie, Venus Khoury-Ghata, Tahar Ben Jelloun, Andre Velter, Marie-Claire Bancquart, Jean-Claude Pinson, Jacques Dupin
ISBN: 9004367667 ISBN-13(EAN): 9789004367661
Издательство: Brill
Цена: 116890.00 T
Наличие на складе: Невозможна поставка.
Описание: In Earth and Mind : Dreaming, Writing, Being Michael Bishop examines the very recent work of nine major contemporary French and Francophone writers : Yves Bonnefoy, Jacqueline Risset, Salah Stetie, Venus Khoury-Ghata, Tahar Ben Jelloun, Andre Velter, Marie-Claire Bancquart, Jean-Claude Pinson and Jacques Dupin. The issue of writing’s complex relation to the experience of the earth is of central pertinence, involving questions of dreaming, voice, figurativity, emotion, desire, revolt, metaphysics, meaning, poiein and being. Discussion entails close reading of works as well as broad contextualisation and a sensitivity to interrelevancies from writer to writer. Bishop’s book is intended as a companion to his 2014 Dystopie et poiein, agnose et reconnaissance. Seize etudes sur la poesie francaise et francophone contemporaine.

Автор: Todd H.J. Pettigrew, Stephanie M. Pettigrew, Jacques A. Bailly
Название: The Major Works of John Cotta : The Short Discovery (1612) and The Trial of Witchcraft (1616)
ISBN: 9004367160 ISBN-13(EAN): 9789004367166
Издательство: Brill
Цена: 228460.00 T
Наличие на складе: Невозможна поставка.
Описание: This volume presents, for the first time, a critical edition of the works of the early modern English physician John Cotta. No mere country doctor, Cotta spoke out eloquently and courageously against what he saw as abuses in medicine and injustices in the prosecution of witchcraft. Read by important thinkers such as Robert Burton in England, and by colonial administrators in New England, Cotta helped shape two of the most important debates of his time. Included are the full texts of Cotta's Short Discovery and The Trial of Witchcraft, both books painstakingly edited and annotated. Also included is a detailed introduction dealing with Cotta's medical and religious contexts, his extensive learning and much more.

Автор: Lehmann Sylvain, Grassi Jacques
Название: Techniques in Prion Research
ISBN: 3764324155 ISBN-13(EAN): 9783764324155
Издательство: Birkhauser Verlag AG
Цена: 120570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin.Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.Features:Purification of PrPC and the Pathological Isoform of Prion Protein (PrPsc or PrP-res)Animal Models of TSEsCell Culture Models of TSEsPrPsc ImmunohistochemistryWestern Immunoblotting TechniquesAntibody Production and ELISATSE Strain Typing in MiceBiosafety and Decontamination ProceduresCell-free Conversion of Prion ProteinsCytotoxicity of PrP PeptidesCyclic Amplification of Prion Protein MisfoldingPrion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin.Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.Abbreviations.- Transmissible Spongiform Encephalopathies or Prion Diseases (General Introduction).- Purification of PrPC. Purification of the Pathological Isoform of Prion Protein (PrPsc or PrP-res) from Transmissible Spongiform Encephalopathy-affected Brain Tissue.- Rapid Procedure for Purification and Renaturation of Recombinant PrP Protein.- Animal Models of Transmissible Spongiform Encephalopathies: Experimental Infection, Observation and Tissue Collection.- Cell Culture Models of TSEs.- PrPsc Immunohistochemistry. Western Immunoblotting Techniques for the Study of Transmissible Spongiform Encephalopathies. Antibody Production and ELISA, Diagnosis of TSEs, General Considerations.- TSE Strain Typing in Mice. Biosafety and Decontamination Procedures.- Cell-free Conversion of Prion Proteins.- Cytotoxicity of PrP Peptides.- Cyclic Amplification of Prion Protein Misfolding. Guide to Solutions.- Guide to Protocols.- Index