Recent Advances in Diabetes, Rajeev Chawla

Автор: Richardson
Название: Recent Advances in Transthyretin Evolution, Structure and Biological Functions
ISBN: 3642006450 ISBN-13(EAN): 9783642006456
Издательство: Springer
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Цена: 231990.00 T
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Описание: There is a strong interest in transthyretin in connection with protein evolution, medical and clinical research. Transthyretin is a protein found in human blood and cerebrospinal fluid. It is directly involved in the transport of thyroid hormones, and indirectly in that of retinol. This monograph presents various developments and discoveries.

Автор: A. Cato; H. Schaecke; K. Asadullah
Название: Recent Advances in Glucocorticoid Receptor Action
ISBN: 3662046628 ISBN-13(EAN): 9783662046623
Издательство: Springer
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Цена: 174150.00 T
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Автор: Maria Diakonova, PhD
Название: Recent Advances in Prolactin Research
ISBN: 3319121138 ISBN-13(EAN): 9783319121130
Издательство: Springer
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Цена: 130430.00 T
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Описание: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged.

Автор: Maria Diakonova, PhD
Название: Recent Advances in Prolactin Research
ISBN: 3319352768 ISBN-13(EAN): 9783319352763
Издательство: Springer
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Цена: 121890.00 T
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Описание: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors.

Название: Best of Five MCQS for the Endocrinology and Diabetes SCE
ISBN: 0198729332 ISBN-13(EAN): 9780198729334
Издательство: Oxford Academ
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Цена: 51730.00 T
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Описание: Best of Five MCQs for the Endocrinology and Diabetes SCE is designed specifically for this new high-stakes exam. It contains over 300 best of five questions with explanatory answers, each accurately reflecting the layout of questions in the exam.

Автор: Turner, Helen; Wass, John
Название: Oxford Handbook of Endocrinology and Diabetes
ISBN: 0198567391 ISBN-13(EAN): 9780198567394
Издательство: Oxford Academ
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Цена: 31680.00 T
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Описание: This practical and concise guide to endocrinology and diabetes has been fully revised for the new edition. Covering clinical investigations and management of both common and rare conditions, it includes the protocols and clinical information necessary for the management of patients with endocrine and diabetic disorders.

Автор: Samantha J. Richardson; Vivian Cody
Название: Recent Advances in Transthyretin Evolution, Structure and Biological Functions
ISBN: 3642420710 ISBN-13(EAN): 9783642420719
Издательство: Springer
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Цена: 204970.00 T
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Описание: Since its ?rst description in 1942 in both serum and cerebrospinal ?uid, transthyretin (TTR) has had an eventful history, including changes in name from “prealbumin” to “thyroxine-binding prealbumin” to “transthyretin” as knowledge increased about its functions. TTR is synthesised in a wide range of tissues in humans and other eutherian mammals: the liver, choroid plexus (blood- cerebrospinal ?uid barrier), retinal pigment epithelium of the eye, pancreas, intestine and meninges. However, its sites of synthesis are more restricted in other vertebrates. This implies that the number of tissues synthesising TTR during vertebrate evolution has increased, and raises questions about the selection pressures governing TTR synthesis. TTR is most widely known as a distributor of thyroid hormones. In addition, TTR binds retinol-binding protein, which binds retinol. In this way, TTR is also involved with retinoid distribution. More recently, TTR has been demonstrated to bind a wide variety of endocrine disruptors including drugs, pollutants, industrial compounds, heavy metals, and some naturally occurring plant ?avonoids. These not only interfere with thyroid hormone delivery in the body, but also transport such endocrine disruptors into the brain, where they have the potential to accumulate.

Название: Oxford Handbook of Endocrinology and Diabetes
ISBN: 0199644438 ISBN-13(EAN): 9780199644438
Издательство: Oxford Academ
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Цена: 39060.00 T
Наличие на складе: Невозможна поставка.
Описание: This practical and concise guide to endocrinology and diabetes has been fully revised for the new edition. Covering clinical investigations and management of both common and rare conditions, it includes the protocols and clinical information necessary for the management of patients with endocrine and diabetic disorders.

Автор: Johnstone Michael T., Veves Aristidis
Название: Diabetes and Cardiovascular Disease
ISBN: 1588294137 ISBN-13(EAN): 9781588294135
Издательство: Springer
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Цена: 241310.00 T
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Описание: The importance of this text on Diabetes and Cardiovascular Disease is evident by the magnitude of the population affected by diabetes mellitus. The prognosis of patients with diabetes mellitus who develop overt clinical cardiovascular disease is much worse than those cardiovascular patients free of diabetes mellitus.