Drug Delivery Across Physiological Barriers, Jakub Sarto
Автор: Anya Hillery Название: Drug Delivery ISBN: 1138407364 ISBN-13(EAN): 9781138407367 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Невозможна поставка. Описание: This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments
Автор: Jakub Sarto Название: Handbook of Polyester Drug Delivery Systems ISBN: 1681176920 ISBN-13(EAN): 9781681176925 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: Polymers that can degrade into biologically compatible components under physiologic conditions are advantageous for the preparation of drug delivery systems (DDS). The use of biodegradable polymers precludes the need for retrieval at the conclusion of the dosing regimen, thereby avoiding the potential complications associated with the use of non-degradable systems. Homopolymers and copolymers, obtained from glycolide, lactide and caprolactone and trimethylene carbonate (TMC), are the most commonly considered drug delivery vehicles. However, there are still few implantable drug delivery systems obtained from biodegradable polymers. Attachment of drugs to high molecular weight polymers can significantly improve both tumor targeting and therapeutic efficacy due to the enhanced permeability and retention effect observed in tumour tissue. However, the commercial availability of well-defined water-soluble polymeric systems with narrow polydispersities that are biocompatible, nontoxic, and nonimmunogenic is rather limited. Even with the progress of novel materials, polyesters still endure at the controls of drug delivery technologies. The book provides comprehensive information of polyester drug delivery systems that covers a wide-ranging of materials design, manufacturing techniques, and applications. Polyglycolide (PGA) was one of the first biodegradable synthetic polymers investigated for biomedical applications and was synthesised for the first time in 1954. In the beginning, it was not considered for biomedical applications because of its thermal and hydrolytic instability. However, the ability to degrade inside the human body became a great advantage.
Название: Delivery Strategies for Antisense Oligonucleotide Therapeutics ISBN: 1138505897 ISBN-13(EAN): 9781138505896 Издательство: Taylor&Francis Рейтинг: Цена: 224570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific targeting and cellular uptake, manipulating subcellular distribution and producing liposomal delivery systems for antisense agents are comprehensively covered in this volume. This book links review-type articles with contributions that contain exciting never-before-published data on the cellular delivery of oligonucleotides. It stimulates reading for both established researchers and newcomers to the antisense field.
Название: Biodrug Delivery Systems ISBN: 1138116793 ISBN-13(EAN): 9781138116795 Издательство: Taylor&Francis Рейтинг: Цена: 81650.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An international group of leading experts in drug development and biopharmaceutical science discusses the latest advances in biodrug delivery systems and associated techniques.
Автор: Lino Messana Название: Nanotechnology in Drug Delivery: Fundamentals, Design & Applications ISBN: 1681176912 ISBN-13(EAN): 9781681176918 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy. Nanotechnology is the study, design, creation, synthesis, manipulation, and application of materials, devices, and systems at the nanometre scale. Recent years have witnessed unprecedented growth of research and applications in the area of nanoscience and nanotechnology. There is increasing optimism that nanotechnology, as applied to medicine, will bring significant advances in the diagnosis and treatment of disease. Anticipated applications in medicine include drug delivery, both in vitro and in vivo diagnostics, nutraceuticals and production of improved biocompatible materials. Engineered nanoparticles are an important tool to realise a number of these applications. This book presents reviews and original matter from renowned experts working in the interdisciplinary field of nanotechnology use in drug delivery. From their direct and current practice, the readers can realise a wide vision on the new and enduring potentialities of nanotechnology application of drug delivery. Nanotechnology is expected to have a revolutionary impact on medicine. Nanoparticles can play a major role in medicine and especially in diagnosis and therapy of cancer, cardiovascular diseases and infectious diseases. To further the application of nanoparticles in pharmacy, it is important that the systems are stable, capable of being functionalized, biocompatible and directed to specific target sites in the body after systemic administration. Nanotechnology is on its way to make a big impact in Pharmaceutical and Medical diagnostics sciences. A dynamic collaboration is observed within the Researchers, Government, Pharmaceutical - Biomedical companies and educational institutions all over the world in developing the nanotechnology applications in advanced medicine and patient care. It is expected that the forthcoming generations of nano products will have target specificity, may carry multiple drugs and could potentially release the payloads at varying time intervals. Pharmaceutical education in India is also taking significant steps in incorporating courses as well as offering specialization in nanotechnology and its applications in Pharmaceutical scenario.
Автор: Lino Messana Название: Colloids in Drug Delivery ISBN: 1681176998 ISBN-13(EAN): 9781681176994 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: Nanomedicine, or medicine using nanometric devices, has emerged in the past decade as an exhilarating domain that can help to solve a number of problems linked to unsatisfactory therapeutic responses of so-called old drugs. This dissatisfaction stems from inadequate biodistribution after a drugs application, which leads to a limited therapeutic response but also to numerous side effects to healthy organs. The biodistribution of drugs encapsulated in a nanoobject that will act as a vector can be modified to tune its therapeutic efficacy. This review provides a general overview of existing colloidal nanovectors: liposomes, polymeric micelles, polymeric vesicles, polymeric nanoparticles (NPs), and dendrimers. We describe their characteristics, advantages and drawbacks, and discuss their use in the treatment of various diseases. Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. This book offers contemporary research in the field by worlds leading experts and colloid scientists who inspect the full spectrum of this rapidly developing science. It presents an overview on extensive range of colloidal drug delivery systems with special focus on vesicular and particulates systems that are being used in research or might be potentially useful as carriers systems for drug or active biomolecules or as cell carriers with application in the therapeutic field. This class of systems is widely used due to excellent drug targeting, sustained and controlled release behavior, higher entrapment efficiency of drug molecules, prevention of drug hydrolysis or enzymatic degradation, and improvement of therapeutic efficacy. These characteristics help in the selection of suitable carrier systems for drug, cell, and gene delivery in different fields. All those concerned with the research, development, and manufacture of drugs will find this a valuable tool, presenting a wealth of research upon which they can build.
Автор: Yitzhak Rosen Название: Drug Delivery: An Integrated Clinical and Engineering Approach ISBN: 1466565942 ISBN-13(EAN): 9781466565944 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Невозможна поставка. Описание: The book integrates clinical and engineering aspects of drug delivery. It discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, and simulations, and describes the latest drug delivery advances involving nanotechnology, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound.
Название: Nanomedicine in Drug Delivery ISBN: 1138072613 ISBN-13(EAN): 9781138072619 Издательство: Taylor&Francis Рейтинг: Цена: 83690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. Nanomedicine in Drug Delivery gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies.
Featuring contributions by leading researchers from around the world, the book examines:
The integration of nanoparticles with therapeutic agents
The synthesis and characterization of nanoencapsulated drug particles
Targeted pulmonary nanomedicine delivery using inhalation aerosols
The use of biological systems--bacteria, cells, viruses, and virus-like particles--as carriers to deliver nanoparticles
Nanodermatology and the role of nanotechnology in the diagnosis and treatment of skin disease
Nanoparticles for the delivery of small molecules, such as for gene and vaccine delivery
The use of nanotechnologies to modulate and modify wound healing
Nanoparticles in bioimaging, including magnetic resonance, computed tomography, and molecular imaging
Nanoparticles to enhance the efficiency of existing anticancer drugs
The development of nanoparticle formulations
Nanoparticles for ocular drug delivery
Nanoparticle toxicity, including routes of exposure and mechanisms of toxicity
The use of animal and cellular models in nanoparticles safety studies
With its practical focus on the design, synthesis, and application of nanomedicine in drug delivery, this book is a valuable resource for clinical researchers and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner. It explores a wide range of promising approaches for the diagnosis and treatment of diseases using cutting-edge nanotechnologies.
Название: Nanodispersions for drug delivery ISBN: 177188701X ISBN-13(EAN): 9781771887014 Издательство: Taylor&Francis Рейтинг: Цена: 133730.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume, Nanodispersions for Drug Delivery, addresses efforts to overcome the shortcomings of conventional dosage forms by exploiting the principles of nanoscience to deliver drugs for medical treatment.
Автор: Amit Singh Название: Stimuli-Responsive Drug Delivery Systems ISBN: 1788011139 ISBN-13(EAN): 9781788011136 Издательство: Royal Society of Chemistry Рейтинг: Цена: 223870.00 T Наличие на складе: Нет в наличии. Описание: This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials.
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