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Gene Editing: An Update, Prerna Pandey, Shiv Sanjeevi


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Автор: Prerna Pandey, Shiv Sanjeevi
Название:  Gene Editing: An Update
ISBN: 9781773614731
Издательство: Mare Nostrum (Eurospan)
Классификация:
ISBN-10: 1773614738
Обложка/Формат: Hardback
Вес: 0.00 кг.
Дата издания: 30.01.2019
Серия: Medicine
Язык: English
Размер: H 229 X W 152
Читательская аудитория: Professional and scholarly
Ключевые слова: Science: general issues,Genetics (non-medical),Medical genetics, SCIENCE / General
Подзаголовок: An update
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Поставляется из: Англии
Описание: Examines various aspects of gene editing, including an extensive overview about the tools that are used in editing of genes and related concepts. The book includes definitions of genomic editing, gene editing and the Cas system.

The Selfish Gene: 40th Anniversary Edition

Автор: Dawkins Richard
Название: The Selfish Gene: 40th Anniversary Edition
ISBN: 0198788606 ISBN-13(EAN): 9780198788607
Издательство: Oxford Academ
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Цена: 7750.00 T
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Описание: The 40th anniversary edition of the million copy international bestseller, with a new epilogue from the author. As relevant and influential today as when it was first published, this classic exposition of evolutionary thought, widely hailed for its stylistic brilliance and deep scientific insights, stimulated whole new areas of research.

Gene editing, law, and the environment

Название: Gene editing, law, and the environment
ISBN: 1138051128 ISBN-13(EAN): 9781138051126
Издательство: Taylor&Francis
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Цена: 148010.00 T
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Описание: This book considers the existing scientific, legal, and political regulatory regimes that pertain to gene editing. By exploring such a range of potential applications of gene editing - not only biomedical, but also agricultural and ecological - the book reveals numerous crossovers and disjunctions between approaches to the human and the nonhuman.

Genome Editing

Автор: Turksen
Название: Genome Editing
ISBN: 3319341464 ISBN-13(EAN): 9783319341460
Издательство: Springer
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Цена: 130430.00 T
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Описание:

This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions.
Genome Editing is an essential, of-the-moment contribution to this rapidly growing field. Drawing from a wealth of international perspectives, it presents novel techniques and applications for the engineering of the human genome. This book is essential reading for all clinicians and researchers in stem cells, regenerative medicine, genomics, biochemical and biomedical engineering- especially those interested in learning more about genome editing and applying it in a targeted, specific way.

Genome Editing

Автор: Toni Cathomen; Matthew Hirsch; Matthew Porteus
Название: Genome Editing
ISBN: 1493935070 ISBN-13(EAN): 9781493935079
Издательство: Springer
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Цена: 130610.00 T
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Описание: "American Society of Gene & Cell Therapy"--Cover.

Genome Editing in Animals

Автор: Izuho Hatada
Название: Genome Editing in Animals
ISBN: 1493971271 ISBN-13(EAN): 9781493971275
Издательство: Springer
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Цена: 130430.00 T
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Описание:

1. Construction and Evaluation of Zinc Finger Nucleases

Hiroshi Ochiai and Takashi Yamamoto

2. Current Overview of TALEN Construction Systems

Tetsushi Sakuma and Takashi Yamamoto

3. CRISPR/Cas9

Izuho Hatada and Takuro Horii

4. Computational Prediction of CRISPR/Cas9 Target Sites Reveals Potential Off-Target Risks in Human and Mouse

Qingbo Wang and Kumiko Ui-Tei

5. Genome Editing of Mouse by Cytoplasmic Injection

Takuro Horii and Izuho Hatada

6. Genome Editing in Mouse Zygotes and Embryonic Stem Cells by Introducing sgRNA/Cas9 Expressing Plasmids

Taichi Noda, Asami Oji, and Masahito Ikawa

7. Genome Editing in Mouse and Rat by Electroporation

Takehito Kaneko

8. Generation of Knock-in Mouse by Genome Editing

Wataru Fujii

9. Genome Editing of Rat

Takehito Kaneko

10. Gene Targeting in Rabbits: Single-step Generation of Knockout Rabbits by Microinjection of CRISPR/Cas9 Plasmids

Yoshihiro Kawano and Arata Honda

11. Genome Editing of Pig

Masahito Watanabe and Hiroshi Nagashima

12. Genome Editing of Monkey

Zhen Liu, Yijun Cai, and Qiang Sun

13. Genome Editing Mediated by Primordial Germ Cell in Chicken

Jae Yong Han and Hong Jo Lee

14. CRISPR/Cas9-mediated Targeted Knock-in of Exogenous Reporter Genes in Zebrafish

Atsuo Kawahara

15. Genome Editing of Medaka

Satoshi Ansai and Masato Kinoshita

16. A Simple Protocol for Loss-of-Function Analysis in Xenopus tropicalis Founders using the CRISPR-Cas System

Yuto Sakane, Ken-ich T Suzuki, and Takashi Yamamoto

17. Genome Editing of Silkworms

Takuya Tsubota and Hideki Sezutsu

18. Genome Editing in the Cricket, Gryllus bimaculatus

Takahito Watanabe, Sumihare Noji, and Taro Mito

19. Genome Editing of the Ascidian Ciona intestinalis with TALE Nuclease

Yasunori Sasakura, Keita Yoshida, and Nicholas Treen

20. &

Targeted Genome Editing Using Site-Specific Nucleases

Автор: Takashi Yamamoto
Название: Targeted Genome Editing Using Site-Specific Nucleases
ISBN: 4431562354 ISBN-13(EAN): 9784431562351
Издательство: Springer
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Цена: 149060.00 T
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Описание: This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

Gene Editing, Law, and the Environment

Название: Gene Editing, Law, and the Environment
ISBN: 0367138468 ISBN-13(EAN): 9780367138462
Издательство: Taylor&Francis
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Цена: 46950.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book considers the existing scientific, legal, and political regulatory regimes that pertain to gene editing. By exploring such a range of potential applications of gene editing - not only biomedical, but also agricultural and ecological - the book reveals numerous crossovers and disjunctions between approaches to the human and the nonhuman.

Genome editing and engineering :

Название: Genome editing and engineering :
ISBN: 1107170370 ISBN-13(EAN): 9781107170377
Издательство: Cambridge Academ
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Цена: 166850.00 T
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Описание: Endonuclease-based genomic engineering is a field with broad potential applications for the treatment of human disease. This complete reference covers the discovery, basic science and application, making it invaluable for researchers and graduate students across the biomedical sciences, and those in the biotechnology and pharmaceutical industries.

Biocommunication and Natural Genome Editing

Автор: G?nther Witzany
Название: Biocommunication and Natural Genome Editing
ISBN: 9400791143 ISBN-13(EAN): 9789400791145
Издательство: Springer
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Цена: 156720.00 T
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Описание: This book provides a uniform description of all key levels of communication in the organismic kingdoms of plants, fungi, animals, bacteria and additionally the natural genome editing competences of viruses based on the most recent empirical data.

Genome Editing in Neurosciences

Автор: Rudolf Jaenisch; Feng Zhang; Fred Gage
Название: Genome Editing in Neurosciences
ISBN: 3319601911 ISBN-13(EAN): 9783319601915
Издательство: Springer
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Цена: 46570.00 T
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Описание: This book is open access under a CC BY 4.0 license.

CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease.

This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.



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