Demystifying Opioid Conversion Calculations: A Guide for Effective Dosing, Mary Lynn McPherson

Автор: A.F. Casy; R.T. Parfitt
Название: Opioid Analgesics
ISBN: 1489905871 ISBN-13(EAN): 9781489905871
Издательство: Springer
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Цена: 186330.00 T
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Описание: The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal­ gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono­ logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.

Автор: Branden D. Nemecek, Drayton A. Hammond
Название: Demystifying Drug Dosing in Renal Dysfunction
ISBN: 158528551X ISBN-13(EAN): 9781585285518
Издательство: Mare Nostrum (Eurospan)
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Цена: 57690.00 T
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Описание: Chronic kidney disease affects approximately 30 million adults in the United States. Demystifying Drug Dosing in Renal Dysfunction supports your clinical decision process with guidance on dosage adjustments and monitoring in renal dysfunction for medications, subpopulations, and renal replacement modalities. This time-saving resource provides helpful tips and support for a range of clinical situations, including:AntiepilepticsCardiovascular DiseaseCo-morbidities associated with chronic kidney diseaseCritical illnessInfectious diseasesOncologyPain managementPediatricsPsychiatryTherapeutic plasma exchangeTransplantation

Автор: K.O. Stumpe; Karin Kraft; Alan I. Faden
Название: Opioid Peptides and Blood Pressure Control
ISBN: 3540189351 ISBN-13(EAN): 9783540189350
Издательство: Springer
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Цена: 102480.00 T
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Описание: A. , FADEN, K. KRAFr, and K. O. STUMPE Following the discovery of the pentapeptide enkephalins in 1975, a number of endogenous opioid peptides and opiate receptors have been identified. Endogenous opioids and opiate-receptor mechanisms have been implicated in a variety of regulat- ory and dysregulatory functions including analgesia, cardiovascular regulation, shock, hypertension, traumatic spinal cord and brain injury, stroke, immune func- tion, feeding behavior, diuresis, gastrointestinal motility, and respiratory control, among others. Over the past 10 years, many studies have demonstrated a relationship between endogenous opioids and the cardiovascular system under both homeostatic and pathophysiological conditions. Opioids and opiate receptors have been found in various cardioregulatory sites within the brain and spinal cord, as well as in peripheral tissues such as sympathetic ganglia, adrenal gland, and heart. Both endogenous opioids and exogenous opiates have been shown to produce potent cardiovascular effects following central nervous system or systemic administration. Opiate-receptor antagonists have been demonstrated to reverse hypotension from sepsis, hypo- volemia, and anaphylaxis; such studies have been used to infer activity of endogenous opioid systems in shock. Changes in tissue concentrations of endogenous opioids and or opiate receptors have been found after shock and hypertension, further implying a role for opioid systems in the etiology of these conditions. In addition, modification of opiate receptor regulation, receptor binding, or opioid metabolism has also been used to establish a potential role for endogenous opioid systems in cardiovascular control and dyscontrol.

Автор: Smith Howard S.
Название: Opioid Therapy in the 21st Century
ISBN: 0199844976 ISBN-13(EAN): 9780199844975
Издательство: Oxford Academ
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Цена: 50150.00 T
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Описание: Opioid Therapy in the 21st Century, Second Edition provides clinicians with up-to-date, evidence-based information about appropriate opioid use, including the potential benefits and adverse affects of the therapy.

Автор: Campbell
Название: A Time-Release History of the Opioid Epidemic
ISBN: 3319917870 ISBN-13(EAN): 9783319917870
Издательство: Springer
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Цена: 51230.00 T
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Описание: From the isolation and development of the first alkaloids with morphine that relieved pain within the home and on the battlefield, to the widespread use of nostrums and the addiction crisis that ensued, to the dissemination of drugs by what became known as Big Pharma after the World Wars;

Автор: Santi M. Spampinato
Название: Opioid Receptors
ISBN: 1493955500 ISBN-13(EAN): 9781493955503
Издательство: Springer
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Цена: 111790.00 T
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Описание: Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors. Other methods cover the cellular detection and trafficking of opioid receptors in vitro and in vivo. Procedures aimed to investigate signaling pathways modulated by opioid receptors and model systems to study opioid receptor-mediated functions are also included. Finally, methods to assay behavioral effects mediated by opioid receptors are described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective introductions, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Wide-ranging and authoritative, Opioid Receptors: Methods and Protocols will help both experienced and new entrants in this field to carry out their experiments successfully and with new inspiration.

Автор: Merrill Norton
Название: The Pharmacist`s Guide to Opioid Use Disorders
ISBN: 1585285862 ISBN-13(EAN): 9781585285860
Издательство: Mare Nostrum (Eurospan)
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Цена: 38450.00 T
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Описание: Pharmacists and other healthcare practitioners are on the frontlines of the fight against opioid use disorders. Through their training and direct contact with patients, they are uniquely qualified to prevent and manage misuse of opioids and other drugs. But knowing where and how to start isn’t always obvious. The Pharmacist’s Guide to Opioid Use Disorders provides a comprehensive resource for all aspects of this devastating epidemic, starting with a discussion of the neuroscience of substance use disorders. Edited by Merrill Norton, PharmD, ICCDP-D, a Clinical Associate Professor at the University of Georgia College of Pharmacy and a specialist in psychopharmacology and substance use disorders, it compiles the most current information, science, and best practices in one concise guide.Readers will benefit from the insights and lessons described in each chapter, as well as the clinical pearls—practice points—gleaned from the writers’ medical, nursing, and pharmacy clinical practices. The Guide also provides useful information in its appendices, including references and resources and a naloxone products table.

Автор: Ballantyne, Jane; Tauben, David J.
Название: Expert Decision Making on Opioid Treatment
ISBN: 0199768889 ISBN-13(EAN): 9780199768882
Издательство: Oxford Academ
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Цена: 64410.00 T
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Описание: This book offers expert, balanced, concise guidance on how clinicians can navigate a number of complex considerations to formulate a treatment plan for chronic pain that either includes or advisedly excludes opioids.

Автор: Jutkiewicz
Название: Delta Opioid Receptor Pharmacology and Therapeutic Applications
ISBN: 3319951319 ISBN-13(EAN): 9783319951317
Издательство: Springer
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Цена: 107130.00 T
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Описание: This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson’s disease. Throughout the book, the DOR system as a target for drug development will be discussed.

Автор: Annette M. Matthews; Jonathan C. Fellers
Название: Treating Comorbid Opioid Use Disorder in Chronic Pain
ISBN: 3319298615 ISBN-13(EAN): 9783319298610
Издательство: Springer
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Цена: 83850.00 T
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Описание: ГЇВїВЅ This in-depth text addresseshow to approach and treat the chronic pain patient struggling with problematicopioid use. The last part of the book addressestreating comorbid pain and opioid use disorder in different medical settings and thetreatment of co-occurring mental illnesses and substance abuse.

Автор: A.F. Casy; R.T. Parfitt
Название: Opioid Analgesics
ISBN: 0306421305 ISBN-13(EAN): 9780306421303
Издательство: Springer
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Цена: 243800.00 T
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Описание: The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal- gesics particularly relevant and timely.

Автор: Cynthia J. Watkins
Название: Pharmacology Clear & Simple: A Guide to Drug Classifications and Dosage Calculations
ISBN: 0803666527 ISBN-13(EAN): 9780803666528
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 65170.00 T
Наличие на складе: Невозможна поставка.
Описание: This thoroughly updated seventh edition includes everything you need to know about the rehabilitation management of adult patients, from integrating basic surgical, medical, and therapeutic interventions to how to select the most appropriate evaluation procedures, develop rehabilitation goals, and implement a treatment plan. Includes 60 video clips.