Neglected Tropical Diseases: Drug Discovery and Development, David C. Swinney, Michael Pollastri, Raimund Mannh
Автор: Mary Ann McDowell; Sima Rafati Название: Neglected Tropical Diseases - Middle East and North Africa ISBN: 3709119839 ISBN-13(EAN): 9783709119839 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume covers the most prevalent neglected tropical diseases (NTDs) found in over 20 Middle East and North Africa countries. Includes an extensive discussion on disease burden, clinical manifestation and control approaches for individual diseases.
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.
In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.
Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Автор: Carlos Franco-Paredes; Jos? Ignacio Santos-Preciad Название: Neglected Tropical Diseases - Latin America and the Caribbean ISBN: 3709114217 ISBN-13(EAN): 9783709114216 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book addresses the major neglected tropical diseases (NTDs) – based on their prevalence and the years of healthy life lost to disability – in Latin American and Caribbean countries. These include Chagas disease, leishmaniasis, hookworm infection, and other soil-transmitted helminth infections, followed by dengue, schistosomiasis, leishmaniasis, leprosy, cysticercosis, bartonellosis, Plasmodium vivax malaria, and onchocerciasis. Topics like disease burden, major manifestations and approaches to the control and elimination of NTDs in Latin America and the Caribbean are discussed in detail. As such, the book will be of general interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of this region of the world.
Автор: Kristensson Krister Название: Neglected Tropical Diseases and Conditions of the Nervous Sy ISBN: 146148099X ISBN-13(EAN): 9781461480990 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines diseases and conditions that occur primarily in remote rural or poor urban areas of low-income countries. It provides information on how these diseases affect the human nervous systems.
Название: Medicinal Chemistry of Neglected Tropical Diseases ISBN: 1138541249 ISBN-13(EAN): 9781138541245 Издательство: Taylor&Francis Рейтинг: Цена: 178640.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The book focuses on medicinal chemistry research into developing effective drugs for the treatment of Neglected Tropical Diseases. The challenge of developing novel drugs and countering resistance to the available drugs requires indepth & updated knowledge on the subject area which this book is aimed at providing for an enthusiastic researcher.
Автор: Carlos Franco-Paredes; Jos? Ignacio Santos-Preciad Название: Neglected Tropical Diseases - Latin America and the Caribbean ISBN: 3709148405 ISBN-13(EAN): 9783709148402 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Neglected tropical diseases represent some of the most common infections of the poor in Latin American and the Caribbean. Each chapter of this book covers a major disease, focusing on disease burden, major manifestations and approaches to control.
Автор: Singh Название: Neglected Tropical Diseases - South Asia ISBN: 3319684922 ISBN-13(EAN): 9783319684925 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Поставка под заказ. Описание: This book covers all aspects of Neglected Tropical Diseases in the region of South Asia. NTDs constitute a significant part of the total disease burden in this geographic area, including soil borne helminth infections, vector borne viral infections, protozoan infections and a few bacterial infections. The current volume covers the most common neglected viral, bacterial and protozoan infections. On top of that, the last part of the volume is dedicated to the management of neglected tropical diseases.
Автор: Roy M Anderson Название: Mathematical Models for Neglected Tropical Diseases: Essential To ISBN: 0128032561 ISBN-13(EAN): 9780128032565 Издательство: Elsevier Science Рейтинг: Цена: 179660.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology.
Advances in Parasitology includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.
The 2013 impact factor is 4.36.
Автор: McDowell Название: Neglected Tropical Diseases - Middle East and North Africa ISBN: 3709116120 ISBN-13(EAN): 9783709116128 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Middle East and North Africa (MENA) is highly endemic for several neglected tropical diseases (NTDs), including viral, bacterial, protozoan and helminth infections. This new volume covers the most prevalent NTDs found in about 22 MENA countries emphasizing the disease burden, clinical manifestations and control approaches. Each individual chapter deals with one specific disease and is written by a group of experts on that topic.
Автор: Miguel Kottow Название: Bioethics and Neglected Diseases ISBN: 1536153338 ISBN-13(EAN): 9781536153330 Издательство: Nova Science Рейтинг: Цена: 149940.00 T Наличие на складе: Невозможна поставка. Описание: Neglected diseases are severe conditions that mainly affect the worlds poorest people. Those suffering from neglected diseases are mostly suffering from tropical infections that have failed to receive priority in pharmaceutical research and development programs, as well as in public health policies aimed at improving availability and access to preventive, diagnostic and curative medicine. The World Health Organization has issued a number of documents directing attention to the plight affecting one third of the worlds population, assisted by active support from private organizations, notably the Bill and Melissa Gates Foundation, but the overall situation remains dismal. In the wake of major socioeconomic processes including globalization, steadily growing economic disparity, healthcare inequality, the instability created by rogue states and terrorism, as well as massive migration, and epidemic outbreaks, the features of neglected diseases have been changing. Neglected populations affected by tropical diseases are suffering increasingly from non-infectious degenerative conditions and disabilities due to untreated chronic maladies. Pockets of poverty and neglect can also be detected in high-income countries, contributing to the emergence of new diseases and the reemergence of infections believed to be disappearing such as tuberculosis and the measles. Included in the issues of neglect are rare diseases, mostly of genetic origin, affecting a small number of patients that suffer from multiple life-shortening functional impairment and organ defects. Effective medicines are extremely expensive, allegedly because research and development of appropriate drugs is resources and time consuming, requiring exorbitant prices to recoup investment from a small number of consumers. Bioethics has been tardy in addressing the suffering and destitution of neglected and rare diseases. Convinced that permanently repeated denunciations blunt the sensitivity towards suffering, whereas statistics are bloodless and unable to elicit commitment, this book attempts to explore a different strategy. In an upstream approach, bioethics needs to engage in ethnographic fieldwork that confronts and shares the context in which people suffer, vividly presenting what epidemiological research has blunted into statistical data. Additionally, a downstream approach is suggested, requiring bioethics to vigorously and openly denounce unethical biomedical and pharmaceutical research, misdeeds in registration and marketing of drugs, and misalignment of policies with the unmet healthcare needs of the destitute. More than being critical observers, bioethicists ought to shed lurking conflicts of interests and seek active participation in planning research and public healthcare practices aimed at improving the lives of medically neglected populations.
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