Guide to Cancer Immunotherapy, Suzanne Walker, Elizabeth Prechtel Dunphy

Автор: Karp Daniel D
Название: Handbook of Targeted Cancer Therapy and Immunotherapy
ISBN: 1496389131 ISBN-13(EAN): 9781496389138
Издательство: Lippincott Williams & Wilkins
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Цена: 53190.00 T
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Описание: A must-have resource for oncologists, researchers, and other cancer care professionals! This comprehensive yet concise reference includes clinical trial results of more than 190 targeted therapy and immunotherapy agents. Immunotherapy trial results expanded Tumor immunology section added Recent landmark trial results incorporated FDA approvals highlighted Approach clinical challenges from any direction. Chapters organized by tumor type, pathway, and drug name. Find information quickly and easily, using a color-coded, intuitive format. Small enough to fit in your lab coat pocket. Or, download the eBook to your smartphone or other device for even more convenient referencing. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Автор: Anand Rotte; Madhuri Bhandaru
Название: Immunotherapy of Melanoma
ISBN: 3319480650 ISBN-13(EAN): 9783319480657
Издательство: Springer
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Цена: 186330.00 T
Наличие на складе: Поставка под заказ.
Описание: Introducing metastatic melanomas, this book details diagnosis, clinical symptoms, types and AJCC staging, followed by a discussion of treatment problems and how immunotherapy provided the solution. The immune system, approved drugs and their molecular action are discussed, with the most promising candidates from ongoing clinical trials.

Автор: Xiang-Yang Wang
Название: Immunotherapy of Cancer,128
ISBN: 0128023163 ISBN-13(EAN): 9780128023167
Издательство: Elsevier Science
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Цена: 132500.00 T
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Описание:

Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.

Автор: Donnadieu
Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
ISBN: 3319422219 ISBN-13(EAN): 9783319422213
Издательство: Springer
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Цена: 139310.00 T
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Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.

Название: Immunotherapy of cancer
ISBN: 4431550305 ISBN-13(EAN): 9784431550303
Издательство: Springer
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Цена: 139750.00 T
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Описание: This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunology and the recent advances in clinical trials have opened new avenues with a cancer vaccine in 2010 and immunocheckpoint modulation in 2011, with their approval already granted in the United States. Today, there are no doubts, even among experts in cancer chemotherapy and radiotherapy, that the immune system plays a vital role in tumor eradication. Following American approval, many clinical trials of cancer immunotherapy are being conducted. With this book the reader will readily understand the paradigm shift in cancer treatment and will realize the importance of cancer immunotherapy. The great value of immunotherapy will be obvious, not only for tumor shrinkage but for prolonging patient survival.

Автор: Benjamin Bonavida; Salem Chouaib
Название: Resistance of Cancer Cells to CTL-Mediated Immunotherapy
ISBN: 3319178067 ISBN-13(EAN): 9783319178066
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.

Автор: Mary L. Disis
Название: Immunotherapy of Cancer
ISBN: 1617376450 ISBN-13(EAN): 9781617376450
Издательство: Springer
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Цена: 243800.00 T
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Описание: Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments.

Автор: Britten
Название: Cancer Immunotherapy Meets Oncology
ISBN: 3319051032 ISBN-13(EAN): 9783319051031
Издательство: Springer
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Цена: 139750.00 T
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Автор: Zhang
Название: Progress in Cancer Immunotherapy
ISBN: 9401775532 ISBN-13(EAN): 9789401775533
Издательство: Springer
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Цена: 148020.00 T
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Описание: Thisbook provides readers an extensive overview of recent progress in basicand clinical research on cancer immunotherapy. Thanks to rapid advances inmolecular biology and immunology, it has become increasingly evident thatcancer growth is influenced by host immune responses. With the success of anumber of clinical trials, immunotherapy has become a promising treatmentmodality of cancer. This book covers five major topics, including monoclonalantibodies, biological response modifiers, cancer vaccines, adoptive cellulartherapy and oncolytic viruses. It also examines the combination of differentimmune strategies as well as the combination of immunotherapy with othertreatments to increase anti-tumor effects. Throughthecomprehensive discussion of the topic, the book sheds valuable new light on thetreatment of tumors.

Автор: George C. Prendergast
Название: Cancer Immunotherapy,
ISBN: 0123942969 ISBN-13(EAN): 9780123942968
Издательство: Elsevier Science
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Цена: 107790.00 T
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Описание: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles.

Автор: Yotnda
Название: Immunotherapy of Cancer
ISBN: 1607617854 ISBN-13(EAN): 9781607617853
Издательство: Springer
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Цена: 153720.00 T
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Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.

Автор: Dranoff
Название: Cancer Immunology and Immunotherapy
ISBN: 3642141358 ISBN-13(EAN): 9783642141355
Издательство: Springer
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Цена: 191560.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.