Let`s Eat Bugs!: A Thought- Provoking Introduction to Edible Insects for Adventurous Teens and Adults (2nd Edition), Grassi Mk
Автор: Lehmann Sylvain, Grassi Jacques Название: Techniques in Prion Research ISBN: 3764324155 ISBN-13(EAN): 9783764324155 Издательство: Birkhauser Verlag AG Цена: 120570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin.Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.Features:Purification of PrPC and the Pathological Isoform of Prion Protein (PrPsc or PrP-res)Animal Models of TSEsCell Culture Models of TSEsPrPsc ImmunohistochemistryWestern Immunoblotting TechniquesAntibody Production and ELISATSE Strain Typing in MiceBiosafety and Decontamination ProceduresCell-free Conversion of Prion ProteinsCytotoxicity of PrP PeptidesCyclic Amplification of Prion Protein MisfoldingPrion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin.Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.Abbreviations.- Transmissible Spongiform Encephalopathies or Prion Diseases (General Introduction).- Purification of PrPC. Purification of the Pathological Isoform of Prion Protein (PrPsc or PrP-res) from Transmissible Spongiform Encephalopathy-affected Brain Tissue.- Rapid Procedure for Purification and Renaturation of Recombinant PrP Protein.- Animal Models of Transmissible Spongiform Encephalopathies: Experimental Infection, Observation and Tissue Collection.- Cell Culture Models of TSEs.- PrPsc Immunohistochemistry. Western Immunoblotting Techniques for the Study of Transmissible Spongiform Encephalopathies. Antibody Production and ELISA, Diagnosis of TSEs, General Considerations.- TSE Strain Typing in Mice. Biosafety and Decontamination Procedures.- Cell-free Conversion of Prion Proteins.- Cytotoxicity of PrP Peptides.- Cyclic Amplification of Prion Protein Misfolding. Guide to Solutions.- Guide to Protocols.- Index
Автор: Anna Grassi & Cristina Kollinger Collesei Название: Developing Spanish Libro Dos ISBN: 0713679212 ISBN-13(EAN): 9780713679212 Издательство: A & C Black Рейтинг: Цена: 19790.00 T Наличие на складе: Невозможна поставка. Описание: A series of three photocopiable activity books for teaching Spanish to beginners, suitable for both primary and secondary schools, extra-curricular clubs and to use at home. The series provides lively, appealing teaching resources that encourage the acquisition and immediate use of Spanish in a communicative and natural way.
Автор: Anna Grassi & Cristina Kollinger Collesei Название: Developing Spanish Libro Uno ISBN: 0713679301 ISBN-13(EAN): 9780713679304 Издательство: A & C Black Рейтинг: Цена: 24740.00 T Наличие на складе: Невозможна поставка. Описание: A series of three photocopiable activity books for teaching Spanish to beginners, suitable for both primary and secondary schools, extra-curricular clubs and to use at home. The series provides lively, appealing teaching resources that encourage the acquisition and immediate use of Spanish in a communicative and natural way.
Автор: Grassi Duccio Название: Duccio Grassi: On Spaces ISBN: 8831729527 ISBN-13(EAN): 9788831729529 Издательство: Неизвестно Рейтинг: Цена: 41380.00 T Наличие на складе: Невозможна поставка. Описание:
Italian retail designer Duccio Grassi (born 1954) is celebrated internationally for his ability to create mesmerizing store interiors: his clients include Max Mara in New York and Zara's Rome store, and his sensuously sculptural and luminous spaces are spread out over the centers of luxury fashion, from Tokyo, Dubai, Hong Kong and New York to Milan and London. This book explores Grassi's acclaimed, highly innovative contributions to the discipline of retail design, examining the qualities that have made him one of the foremost ambassadors of Italian elegance throughout the world. Testimonies from Sheikh Mana Bin Khalifa Al Maktoum, Luigi Maramotti and Mario Nanni underscore his stylistic language, and are buttressed by illustrations documenting his best-known projects across the world.
In this work famous Italyan historian Fabio L. Grassi addresses Russian conquest of North-Western Caucasus, the massacre and expulsion of the natives, their forced migration into the Ottoman lands and the economic, political and socio-cultural impact of these events along with the struggle of the Circassians for acknowledgement and remembrance.
"A New Homeland" enlightens the tragic concequences of the colonialist policies implemented by the Trarist regime in the Caucasus and the place of the refugees and their descendants in the formation of the modern Turkish nation.
The book also includes the transcription of very important but neglected documents in French and in Italian. Also fort his reason, Fabio L. Grassi's work deserves to be welcomed as an important contribution to our knowledge of an event one must absolutly know to understand the history of late Ottoman Empire and modern Turkey.
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Istanbul Aydin University (IAU) has been providing flexible and relevant education to students, giving them both knowledge and opportunities. IAU is one of the best Turkish Universities that improves lives by producing leaders to society need, has programs suitable for and relevant to all life stages.
Автор: Van Wie Paul D., Grassi Kiera, Mutum Hannah Название: Franklin Square ISBN: 1531650112 ISBN-13(EAN): 9781531650117 Издательство: Неизвестно Цена: 29420.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
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