Автор: Ashley Wilber Название: Glutathione: Dietary Sources, Role in Cellular Functions & Therapeutic Effects ISBN: 1634633725 ISBN-13(EAN): 9781634633727 Издательство: Nova Science Рейтинг: Цена: 257650.00 T Наличие на складе: Невозможна поставка. Описание: This book presents, for the first time, a comprehensive analysis and assessment of sustainability of the contemporary civil air transport system, examining its three main components: airports, air traffic control, and airlines. It offers an in-depth examination and quantitative insight into the system`s current and prospective structure and operations, as well as the related effects and impacts.
Автор: Vina Название: Glutathione (1990) ISBN: 1138105643 ISBN-13(EAN): 9781138105645 Издательство: Taylor&Francis Рейтинг: Цена: 433840.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The aim of this important book is to present the reader with developments concerning glutathione research
Автор: H. Sies; A. Wendel Название: Functions of Glutathione in Liver and Kidney ISBN: 3642671349 ISBN-13(EAN): 9783642671340 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The serene phrase, Lest I forget thee, glutathione ..., coined by the Kosowers (1) to describe the state in the 1960's, must be replaced now by something like "Inevitable GSH" in order to characterize the current situation. The surge in interest on the ubiquitous tripeptide has been ama- zing, with publications on GSH running at rates as high as one per day, so that it seemed appropriate to convene international experts for a discussion of recent develop- ments this year. Unlike the two previous meetings in this decade held in Tlibingen in 1973 (2) and in santa Ynez in 1975 (3), the scope was restricted to Functions of Gluta- thione in Liver and Kidney. Only in this way did an in-depth discussion of the current state of knowledge in a limit- ed topic appear possible. The last couple of years have seen a fascinating pro- ductivity in the fields of (a) Regulation of the Glutathione Level in the Liver, (b) Role of y-Glutamyltransferase in Gluta- thione Turnover with emphasis on the renal enzyme, and a critical appraisal of the y-Glutamyl Cycle, (c) Hyd: roperox- ide and Disulfide Metaholism, enriched by the discovery of the nonseleniurn-dependent glutathione peroxidase activ- ity and its relation to the glutathione-S-transferases, and the participation of the 2GSH/GSSG system in redox transitions in intact organ, cells and isolated mito- chondria, and (d) a multitude of Pharmacological and Toxi- cological Aspects related to glutathione, mainly centered on the events leading to liver damage and the protective
Автор: Mohammad Anwar Hossain; Mohammad Golam Mostofa; Pe Название: Glutathione in Plant Growth, Development, and Stress Tolerance ISBN: 3319666819 ISBN-13(EAN): 9783319666815 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Glutathione (γ-glutamyl-cysteinyl-glycine) is a ubiquitously distributed sulfurcontaining antioxidant molecule that plays key roles in the regulation of plant growth, development, and abiotic and biotic stress tolerance. It is one of the most powerful low-molecular-weight thiols, which rapidly accumulates in plant cells under stress. Recent in-depth studies on glutathione homeostasis (biosynthesis, degradation, compartmentalization, transport, and redox turnover) and the roles of glutathione in cell proliferation and environmental stress tolerance have provided new insights for plant biologists to conduct research aimed at deciphering the mechanisms associated with glutathione-mediated plant growth and stress responses, as well as to develop stress-tolerant crop plants. Glutathione has also been suggested to be a potential regulator of epigenetic modifications, playing important roles in the regulation of genes involved in the responses of plants to changing environments. The dynamic relationship between reduced glutathione (GSH) and reactive oxygen species (ROS) has been well documented, and glutathione has been shown to participate in several cell signaling and metabolic processes, involving the synthesis of protein, the transport of amino acids, DNA repair, the control of cell division, and programmed cell death. Two genes, gamma-glutamylcysteine synthetase (GSH1) and glutathione synthetase (GSH2), are involved in GSH synthesis, and genetic manipulation of these genes can modulate cellular glutathione levels. Any fluctuations in cellular GSH and oxidized glutathione (GSSG) levels have profound effects on plant growth and development, as glutathione is associated with the regulation of the cell cycle, redox signaling, enzymatic activities, defense gene expression, systemic acquired resistance, xenobiotic detoxification, and biological nitrogen fixation. Being a major constituent of the glyoxalase system and ascorbate-glutathione cycle, GSH helps to control multiple abiotic and biotic stress signaling pathways through the regulation of ROS and methylglyoxal (MG) levels. In addition, glutathione metabolism has the potential to be genetically or biochemically manipulated to develop stress-tolerant and nutritionally improved crop plants. Although significant progress has been made in investigating the multiple roles of glutathione in abiotic and biotic stress tolerance, many aspects of glutathione-mediated stress responses require additional research.
The main objective of this volume is to explore the diverse roles of glutathione in plants by providing basic, comprehensive, and in-depth molecular information for advanced students, scholars, teachers, and scientists interested in or already engaged in research that involves glutathione. Finally, this book will be a valuable resource for future glutathione-related research and can be considered as a textbook for graduate students and as a reference book for frontline researchers working on glutathione metabolism in relation to plant growth, development, stress responses, and stress tolerance.
Автор: Pal Perjesi Название: Glutathione: Biosynthesis, Functions and Biological Implications ISBN: 1536147400 ISBN-13(EAN): 9781536147407 Издательство: Nova Science Рейтинг: Цена: 215410.00 T Наличие на складе: Невозможна поставка. Описание: Glutathione (GSH) is a ubiquitous tripeptide (γ-L-gluatamyl-Lcysteinyl-glycin) playing an important role in cellular redox homeostasis, defence against electrophilyc reactive species, and control of several cellular events, among others. Most of these cellular functions are related to its tiol (SH) function of the cysteine moiety. With increasing knowledge on the molecular basis of its cellular functions, use of GSH as a nutritional supplement is receiving increasing interest. The present book summarizes the recent literature and new develeopments on three distinct, but closely related topics: Production, biochemical functions, implications and applications of glutathione. The topics cover comprehensive reviews on physico-chemical characterization, pharmacopoeal qualification, biotechnological production, surveys on different analytical methods for its quantitation, and the role of several physiological abnormalities (e.g., cardiac disfunctions, neurological disorders, kidney injuries and different types of cancer) related to non-appropriate biosynthesis and/or metabolism of endogeneous GSH. The information presented represents a valuable source for advanced students, scholars, teachers and scientists (academic and industrial) interested or already engaged in research that involves glutathione.
Автор: D. Grill; Michael M. Tausz; L.J. de Kok Название: Significance of Glutathione to Plant Adaptation to the Environment ISBN: 904815894X ISBN-13(EAN): 9789048158942 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Glutathione is a thiol-containing tripeptide, which appears to be present in nearly all living organisms and which is involved in many important metabolic and physiological processes.
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