Автор: Prerna Pandey Название: RNAi Technologies ISBN: 177361147X ISBN-13(EAN): 9781773611471 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 133760.00 T Наличие на складе: Невозможна поставка. Описание: Discusses how gene silencing methodology has been successfully applied as a therapeutic tool against metabolic disorders, cancer, and infectious diseases. This tool has also been successfully used to improve crop resistance against plant pathogens.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Автор: Baohong Zhang; Edmund J. Stellwag Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 149395749X ISBN-13(EAN): 9781493957491 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Recent stem cell research has revealed that miRNA and RNAi-mediated gene regulation is one of the vital determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination. In RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications, expert authors from laboratories across the globe contribute an accessible compendium of up-to-date, proven methods focused on the study of the titular topic. Divided into three sections, the book first gives a brief introduction to RNAi and miRNAs in stem cells, with a focus on the current status of research and future perspectives, then it continues with detailed methods and protocols for RNAi screening, transfection, and the knockdown of specific genes and pathways in several animal species, including humans and mice, concluding with a section on recently developed methods for identification of miRNAs, including a general protocol for preparation and analysis of miRNA libraries for deep sequencing, knock down of a specific gene using miRNA-based shRNA, and miRNA expression analysis using qRT-PCR. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes highlighting tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications serves as a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and the exciting areas of medicine, including regenerative medicine, aging, cancer, and neurological disorders, that can be advanced through this expanding area of research.
Автор: Baohong Zhang Название: RNAi and Small Regulatory RNAs in Stem Cells ISBN: 1493971069 ISBN-13(EAN): 9781493971060 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Part I: Introduction
1. RNAi Technique in Stem Cell Research: Current Status and Future Perspectives
Gang-Ming Zou
2. RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells
Alexander K. Murashov
Part II: RNA Interference
3. Forward RNAi Screens in Human Hematopoietic Stem Cells
Roman Galeev, Christine Karlsson, Aurйlie Baudet, and Jonas Larsson
4. Silencing of ATP11B by RNAi-Induced Changes in Neural Stem Cell Morphology
