Antibody Engineering, Nevoltris

Автор: Ulf Grawunder; Stefan Barth
Название: Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins
ISBN: 3319468758 ISBN-13(EAN): 9783319468754
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

Автор: Roland E. Kontermann; Stefan D?bel
Название: Antibody Engineering Volume 2
ISBN: 3642011462 ISBN-13(EAN): 9783642011467
Издательство: Springer
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Цена: 214280.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a toolbox of well-established basics and many exciting new techniques in antibody engineering, reflecting the latest hands-on work of key laboratories in this fast-moving field. The new edition is expanded to nearly double the number of protocols.

Автор: Roland E. Kontermann; Stefan D?bel
Название: Antibody Engineering Volume 1
ISBN: 3642011438 ISBN-13(EAN): 9783642011436
Издательство: Springer
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Цена: 279500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a toolbox of well-established basics and many exciting new techniques in antibody engineering, reflecting the latest hands-on work of key laboratories in this fast-moving field. The new edition is expanded to nearly double the number of protocols.

Автор: Roland E. Kontermann; Stefan D?bel
Название: Antibody Engineering Volume 2
ISBN: 3642422764 ISBN-13(EAN): 9783642422768
Издательство: Springer
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Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.

Автор: Benny K. C. Lo
Название: Antibody Engineering
ISBN: 1617373524 ISBN-13(EAN): 9781617373527
Издательство: Springer
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Цена: 163040.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Despite this setback, advances in recombinant DNA techniques over the last 15-20 years have empowered the engineering of recombinant antibodies with desired characteristics, including properties to avoid HAMA.

Автор: McCafferty, John; Hoogenboom, Hennie; Chiswell, Da
Название: Antibody Engineering A Practical Approach (Hardback)
ISBN: 0199635927 ISBN-13(EAN): 9780199635924
Издательство: Oxford Academ
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Цена: 92930.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recombinant DNA techniques have revolutionized the isolation and production of antibodies in recent years, and rapid changes have been made. The time is now ripe to assemble in a Practical Approach volume the protocols which allow the researcher to isolate a new antibody, analyse its properties, format the right antibody molecule or fragment, and produce it in usable quantitites.

Автор: Proetzel
Название: Antibody Methods and Protocols
ISBN: 1617799300 ISBN-13(EAN): 9781617799303
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The rapidly growing field of antibody research is the result of many advancing technologies allowing current developments to take advantage of molecular engineering to create tailor-made antibodies.  Antibody Methods and Protocols attempts to provide insight into the generation of antibodies using in vitro and in vivo approaches, as well as technical aspects for screening, analysis, and modification of antibodies and antibody fragments.  The detailed volume is focused on basic protocols for isolating antibodies and, at the same time, it selects a range of specific areas with the aim of providing guides for the overall process of antibody isolation and characterization as well as protocols for enhancing classical antibodies and antibody fragments.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Antibody Methods and Protocols provides a broad and useful background to support ongoing efforts by novices and experts alike and encourages the development of new imaginative approaches to this vital area of study.

Автор: Robert Aitken (Ed.)
Название: Antibody Phage Display
ISBN: 1603273018 ISBN-13(EAN): 9781603273015
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Поставка под заказ.
Описание: Phage display technology has revolutionized approaches to the analysis of biomedical problems, impacting the fields of immunology, cell biology, biotechnology, pharmacology, and drug discovery. This title provides a resource that guides readers in the design and execution of experiments based around antibody phage display.

Автор: Thomas Kindt
Название: The Antibody Enigma
ISBN: 1468446789 ISBN-13(EAN): 9781468446784
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Antibody Enigma is a somewhat personal view of the antibody diversity question from two investigators who have spent the past 18 years trying to penetrate the enigma.

Автор: Roland E. Kontermann; Stefan D?bel
Название: Antibody Engineering Volume 1
ISBN: 3662495945 ISBN-13(EAN): 9783662495940
Издательство: Springer
Рейтинг:
Цена: 217670.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a toolbox of well-established basics and many exciting new techniques in antibody engineering, reflecting the latest hands-on work of key laboratories in this fast-moving field. The new edition is expanded to nearly double the number of protocols.

Автор: Howard
Название: Basic Methods in Antibody Production & Charact.
ISBN: 0849394457 ISBN-13(EAN): 9780849394454
Издательство: Taylor&Francis
Цена: 68390.00 T
Наличие на складе: Нет в наличии.
Описание: Written for researchers and professionals in the fields of biomedical research, immunology, biochemistry, molecular biology, pathology, and biotechnology, Basic Methods in Antibody Production and Characterization uses a cookbook approach to presenting the methods for the production, characterization, and use of antiboes. Antibodies described include polyclonal and monoclonal and those made by the phage display. Basic Methods in Antibody Production and Characterization focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications.Introductory material accompanies each chapter, giving readers a better understanding of the methods and applications. Ample references arm researchers with many applications pertaining to the particular technology.

Автор: Roberto L. Ceriani
Название: Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment
ISBN: 1461360382 ISBN-13(EAN): 9781461360384
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the anti-breast cancer antibody field the availability of molecular engineering approaches to humanize murine antibodies has induced intense interest in the creation of less immunogenic antibody forms that are now available for clinical testing.