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Summer`s Complaint: My Family`s Courageous, Century-Long Struggle with a Rare Genetic Cancer Syndrome, Kieger Laura
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Автор:
Kieger Laura
Название:
Summer`s Complaint: My Family`s Courageous, Century-Long Struggle with a Rare Genetic Cancer Syndrome
ISBN:
9780998429335
Классификация:
Биографии деятелей науки, техники и медицины
Медицинские работники
ISBN-10: 0998429333
Обложка/Формат: Paperback
Страницы: 258
Вес: 0.33 кг.
Дата издания: 08.11.2017
Язык: English
Размер: 216 x 140 x 15
Поставляется из: США
Описание: Familial Adenomatous Polyposis, or FAP, accounts for roughly 1 percent of hereditary colorectal cancer and carries an extremely high lifetime risk of colon cancer and elevated risks for other exceedingly rare cancers. It is an autosomal dominant condition caused by germline mutations in the adenomatous polyposis coli (APC) gene. By the age of fifty, nearly 99 percent of untreated FAP patients will have developed cancer.
This is the dark shadow that has lingered over one family since at least 1911, when a matriarch was first seen at the Mayo Clinic in Rochester, Minnesota for symptoms that would become commonplace in her descendants. Three of her five children died in their thirties with what theyd come to call summers complaint. Her granddaughter, genetically programmed by a defect on her 5th chromosome also developed cancer, which would ultimately take her life.
This is that familys sometimes tragic story. As told by a daughter, aunt, and sister who has been surrounded by its relentless destruction her entire life, Summers Complaint is at once a testament to the courage of those one family has lost and a journey toward understanding hereditary predispositions to disease and how best to combat them.
This book is a wonderful blend of reflections and medicine. Well-written and deeply informed, Lauras story will especially be of interest to curious readers in the healthcare space. -Maren R
Amazingly well-written and very interesting read Bravo -Katie H
Extremely well-written and very understandable. One of the best books Ive read this year. -Jane T
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