Molecular-Genetic Mechanisms of Development, Zhores A. Medvedev

Автор: Cornel Mulhardt
Название: Molecular Biology and Genomics,
ISBN: 0120885468 ISBN-13(EAN): 9780120885466
Издательство: Elsevier Science
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Цена: 45150.00 T
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Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.

Автор: Brown
Название: Essential Molecular Biology V1
ISBN: 0199636427 ISBN-13(EAN): 9780199636426
Издательство: Oxford Academ
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Описание: This text is a guide to the basic techniques needed for molecular biology. It concentrates on the preparation, purification and handling of nucleic acids.

Автор: Russel Meints
Название: Control Mechanisms in Development
ISBN: 1468432575 ISBN-13(EAN): 9781468432572
Издательство: Springer
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Цена: 46570.00 T
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Автор: De Pomerai David, Pomerai David De
Название: From Gene to Animal: An Introduction to the Molecular Biology of Animal Development
ISBN: 0521388562 ISBN-13(EAN): 9780521388566
Издательство: Cambridge Academ
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Цена: 44350.00 T
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Описание: This 1985 book expounds some of the views on which hierarchies of genes control aspects of animal development. The 1990 second edition, which is reprinted here, is an expanded and largely rewritten version of Dr de Pomerai`s successful first edition.

Автор: Smith Moyra
Название: Molecular Insights Into Development in Humans: Studies in Normal Development and Birth Defects
ISBN: 9814630586 ISBN-13(EAN): 9789814630580
Издательство: World Scientific Publishing
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Цена: 63360.00 T
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Описание: The Aim And Scope Of This Book Is To Review Current Information On Human Development And Processes Of Differentiation That Have Benefited From Breakthrough Analyses In Stem Cell Biology, Elucidation Of Genome And Gene Architecture And Aspects Of Regulation Of Gene Expression, Analysis Of Signaling Systems And Transcription Factor Actions.Insights Into Actions Of Specific Genes And Their Roles In Development Have Been Gathered Through Studies In Patients With Specific Birth Defects, Including Congenital Malformations, Metabolic Defects And Functional Impairments.The Book Is Organized Into Three Sections, The First Dealing With Aspects Of Genomics, Gene Structure And Regulation, Analysis Of Signaling And Function Of Specific Organelles. The Second Section Deals With Molecular Aspects Of Development Of Specific Organs And Structures Such As, Bone, Face, Brain, Heart, Liver, Pancreas, Kidney. The Last Section Deals With Specific Malformations And Tumors That Provide Insight Into Regulation Of Growth. Environmental Factors That Impact Growth And Development Are Also Covered.

Автор: Jean Lauder
Название: Molecular Aspects of Development and Aging of the Nervous System
ISBN: 1475758782 ISBN-13(EAN): 9781475758788
Издательство: Springer
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Описание: The section on Gene and Phenotypic Expression includes discussions of transient gene expression in the nervous system (Herschman), developmental regulation of myelin-associated genes (Gordon et al.

Автор: Ira Black
Название: Cellular and Molecular Biology of Neuronal Development
ISBN: 1461296862 ISBN-13(EAN): 9781461296867
Издательство: Springer
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Цена: 104480.00 T
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Описание: In Chapter 3, Weston and co-workers describe the use of monoclonal antibodies that recognize specific neuronal epitopes (including specific gangliosides) for the purpose of defining heterogeneity in the neural crest, an important model system.

Автор: Romano Regazzi
Название: Molecular Mechanisms of Exocytosis
ISBN: 1441922954 ISBN-13(EAN): 9781441922953
Издательство: Springer
Цена: 156720.00 T
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Описание:

Exocytosis is a fundamental cellular process that is used by eukaryotic cells to release a variety of biological compounds including peptide hormones and neurotransmitters or to insert specific lipids and proteins in the plasma membrane. In recent years, a multidisciplinary approach promoted an extraordinary progress in the understanding of the molecular mechanisms regulating exocytosis. This led to the discovery of a large number of components belonging to the machinery that governs the fusion of secretory vesicles with plasma membranes in different cell systems, including neuronal and endocrine cells. The basic machinery required for vesicle fusion turned out to be well conserved through evolution from yeast to man. So far, because of the large number of components involved, understanding of the molecular basis of exocytosis has remained the privilege of a relatively small group of specialists. This book, written by recognized experts in the field aims at clarifying for a non-specialist audience the role of the key players in the exocytotic process not only in neuronal and endocrine cells but also in a variety of other relevant cell systems. The book represents a unique collection of up-to-date reviews that will introduce researchers and students to the forefront of this rapidly moving and fascinating field.

Автор: Grace Y. Sun; P. Kevin Rudeen; W. Gibson Wood; Yau
Название: Molecular Mechanisms of Alcohol
ISBN: 146128855X ISBN-13(EAN): 9781461288558
Издательство: Springer
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Цена: 121890.00 T
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Описание: Nevertheless, the key to an effective treatment to this problem is through research into understanding the mechan- isms underlying how ethanol interacts with cells and membranes. The second section is directed to the use of cell cuI tures in ethanol research and the usefulness of cell cultures in examination of the effects of ethanol in vitro.

Автор: Marie-Francoise Chesselet
Название: Molecular Mechanisms of Neurodegenerative Diseases
ISBN: 1617371971 ISBN-13(EAN): 9781617371974
Издательство: Springer
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Цена: 231990.00 T
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Описание: The field ofneurodegenerative diseases is undergoing an unprecedented revolution. The past decade has seen the identification of new mutation mecha- nisms, such as triplet repeat expansions, and new genes causing familial forms of common neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. Cellular and animal models based on this genetic information are now available and, importantly, common mechanisms are rapidly emerging among diseases that were once considered unrelated. The field is poised for the development of new therapies based on high throughput screenings and a bet- ter understanding of the molecular and cellular mechanisms leading to neurodegeneration. Molecular Mechanisms of Neurodegenerative Diseases reviews recent progress in this exploding field. By nature, such a book cannot be all inclu- sive. It focuses on Alzheimer's, Parkinson's, and CAG triplet repeat diseases. In the first chapter, Bill Klein reviews the role of A toxicity in the patho- physiology of Alzheimer's disease. This controversial issue is further exam- ined in the context of transgenic models of Alzheimer's disease by LaFerla and colleagues. Sue Griffin and Robert Mrak, and Caleb Finch and collabora- tors, then examine the role of glial cells and inflammation in Alzheimer's disease; a review of the role of proteolysis in the generation of abnormal pro- tein fragments by Hook and Mende-Mueller follows. Therapeutic opportuni- ties offered by a better understanding of Alzheimer's disease pathophysiology are examined by Perry Molinoff and his colleagues at Bristol-Myers Squibb.

Автор: Zhao-Wen Wang
Название: Molecular Mechanisms of Neurotransmitter Release
ISBN: 1627038841 ISBN-13(EAN): 9781627038843
Издательство: Springer
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Цена: 191550.00 T
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Описание: The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release.

Автор: Jeanne Wilson-Rawls; Kenro Kusumi
Название: Innovations in Molecular Mechanisms and Tissue Engineering
ISBN: 331944994X ISBN-13(EAN): 9783319449944
Издательство: Springer
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Цена: 149060.00 T
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Описание: This book marries stem cell biology, tissue engineering, and regenerative biology into a single, interdisciplinary volume. The chapters also explore embryonic stem cells, induced pluripotent stem cells, cardiovascular regeneration, skeletal development, inflammation, polymeric biomaterials, neural injury, cartilage regeneration, regeneration in ambystoma, models for regeneration using salamander and zebrafish, and more. The volume also discusses recent advances and their potential in developing future therapies. Innovations in Molecular Mechanisms and Tissue Engineering combines perspectives from the biomedical, bioengineering, and medical fields to present a cutting-edge, multifaceted picture of the tissue engineering and regenerative medicine fields. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is ideal for scientists, clinicians, and researchers in the fields of stem cell biology, regenerative medicine, biomedical engineering, and tissue engineering.