Sue L. Fielding; Judy S.E. Moyes; Maggie A. Flower Neuroblastoma 9781447116769

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Автор: Sue L. Fielding; Judy S.E. Moyes; Maggie A. Flower
Название: Neuroblastoma
ISBN: 9781447116769
Издательство: Springer
Классификация:

Онкология

Радиотерапия

Педиатрия

Медицинская радиология (лучевая диагностика, лучевая терапия)

ISBN-10: 1447116763
Обложка/Формат: Paperback
Страницы: 168
Вес: 0.42 кг.
Дата издания: 21.12.2011
Язык: English
Размер: 279 x 210 x 10
Основная тема: Medicine & Public Health
Подзаголовок: mIBG in its Diagnosis and Management
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Neuroblastoma is the third most common malignancy of childhood. accounting for 8% of all cancers in patients under 15 years of age. In the majority of cases. by the time neuroblastoma is diagnosed. it has already spread from its site of origin to involve distant sites. Approximately 90% of cases of neuroblastoma can be diagnosed by a combination of techniques including detection of specific tumour markers in the urine. histopathological and immunocytological assessment of involved bone marrow and the characteristic appearances of tumours dem- onstrated by computerised tomography and ultrasonography. However. despite this plethora of techniques. up to. 10% of cases of neuroblastoma are still difficult to diagnose and rely on excisional biopsy of a site of disease. It was against this background that the scintigraphic localisation of neuroblastoma with the radiolabelled guanethidine analogue. mIBG. became available. With mIBG scintigraphy it is now possible to demonstrate the presence of neuro- blastoma (and related tumours) at the primary site. soft tissue sites. in the bone marrow and in cortical bone. in a single investigation. The success of mIBG scintigraphy depends on many factors including the choice of isotope for labelling the mIBG. the equipment used to carry out the procedure. and the manipulation and interpretation of the information obtained. At the Royal Marsden Hospital we have performed over 100 mIBG studies in children. and our advice has frequently been sought by other centres who are. or intend to become.

Neuroblastoma, Sue L. Fielding; Judy S.E. Moyes; Maggie A. Flower