Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes, Yechiel Becker; Gholamreza Darai
Автор: Stuart B. Levy Название: Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids ISBN: 1468439855 ISBN-13(EAN): 9781468439854 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there.
Автор: W. Goebel Название: Genetic Approaches to Microbial Pathogenicity ISBN: 364270588X ISBN-13(EAN): 9783642705885 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Important progress in the elucidation of the mechanisms influencing bacterial pathogenicity has recently been made through the introduction of modem genetic techniques. Molecular cloning allows the isolation of genes for pheno- types that epidemiological surveys have suggested play an important role in pathogenesis. The structural analysis of determinants for pathogenic traits can lead to the identifica- tion not only of the primary sequence but also of the possi- ble secondary and tertiary structures for important viru- lence factors such as toxins and adhesins. From these data, the prediction of antigenic domains suitable for the devel- opment of new vaccines appears to be feasible. The regula- tion of virulence determinants by endogenous and exoge- nous factors can be more clearly understood through the functional analysis of the cloned virulence genes. This volume surveys representative virulence properties of gram-positive and gram-negative bacteria to which the genetic approach has been successfully applied. The exam- ples described here include important bacterial toxins (e.g., diphtheria toxin, cholera toxin, toxic shock syndrome toxin, hemolysins), adhesion structures from E. coli and Neisseria gonorrhoeae, and factors supporting iron uptake, serum resistance, and invasiveness in a variety of bacteria. Both the present state and the possible futural develop- ments of these systems are described.
Автор: Ulrich Dobrindt; J?rg H. Hacker; Catharina Svanbor Название: Between Pathogenicity and Commensalism ISBN: 3642432298 ISBN-13(EAN): 9783642432293 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers various aspects of the interplay between commensal and pathogenic bacteria with their hosts. It details the role commensals play in human development, physiology, protection against pathogens, immunity, and nutrition.
Автор: Jos? P?rez Mart?n; Antonio Di Pietro Название: Morphogenesis and Pathogenicity in Fungi ISBN: 3642428347 ISBN-13(EAN): 9783642428340 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book combines state-of-the-art expertise from a variety of diverse pathogen model systems to provide an update to our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.
Автор: Ulrich Dobrindt; J?rg H. Hacker; Catharina Svanbor Название: Between Pathogenicity and Commensalism ISBN: 3642365590 ISBN-13(EAN): 9783642365591 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers various aspects of the interplay between commensal and pathogenic bacteria with their hosts. It details the role commensals play in human development, physiology, protection against pathogens, immunity, and nutrition.
Автор: Shmuel Razin; Richard Herrmann Название: Molecular Biology and Pathogenicity of Mycoplasmas ISBN: 1475782322 ISBN-13(EAN): 9781475782325 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms;
Автор: J. Hacker; J.B. Kaper Название: Pathogenicity Islands and the Evolution of Pathogenic Microbes ISBN: 364262720X ISBN-13(EAN): 9783642627200 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes.
Автор: Louis Flamand Название: Human Herpesviruses HHV-6A, HHV-6B & HHV-7, ISBN: 0444627030 ISBN-13(EAN): 9780444627032 Издательство: Elsevier Science Рейтинг: Цена: 116780.00 T Наличие на складе: Поставка под заказ. Описание:
Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis.
The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection.
Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases.
Автор: Arvin Название: Human Herpesviruses.2007 ISBN: 0521827140 ISBN-13(EAN): 9780521827140 Издательство: Cambridge Academ Рейтинг: Цена: 585030.00 T Наличие на складе: Невозможна поставка. Описание: This definitive and comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein Barr virus, cytomegalovirus and varicella-zoster virus. The diseases they cause are significant and often recurrent.
Автор: Carlos Lopez; Bernard Roizman Название: The Herpesviruses ISBN: 1461580234 ISBN-13(EAN): 9781461580232 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Bernard Roizman Название: The Herpesviruses ISBN: 1468470140 ISBN-13(EAN): 9781468470147 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The first volume of the series entitled Comprehensive Virology was pub- lished in 1974 and the last is yet to appear. In fact, we felt then, and feel even more strongly now, that viruses, being simpler biological models, could serve as valuable probes for investigating the biology of the far more complex host cell.
Автор: Laure Aurelian; Yechiel Becker Название: Herpesviruses, the Immune System, and AIDS ISBN: 146128810X ISBN-13(EAN): 9781461288107 Издательство: Springer Рейтинг: Цена: 278580.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Shortly after the reeognition of the aequired immunodefieieney syndrome (AIDS) in 1981 (1-3), it was hypothesized that herpesviruses may play an important role in the etiology or pathogenesis of this newly identified syndrome (4,5). This theory was based on the faet that infeetion with herpesviruses was a prominent elinieal feature in nearly all patients with AIDS (3-5). Chronie mueocutaneous herpes simplex virus (HSV) infections were one of the first opportunistie infeetions deseribed in patients with AIDS (3), and both cytomegalovirus (CMV) and HSV infections were extremely common in individuals identified to be at highest risk for aequiring AIDS, such as homosexual men, intravenous drug users and hemophiliaes (4-8). CMVand Epstein-Barr virus (EBV) were also prominent infeetions whieh were suspected as possible etiologic agents of the prolonged fever, wasting, and Iymphadenopathy that often precedes AIDS, frequently referred to as the chronie Iymphadenopathy syndrome (9,10). Subsequent elinieal studies have indeed demonstrated that infeetions with HSV, CMV, EBV, and even varieella- zoster virus (VZV) are frequent opportunistic infeetions wh ich oeeur among AIDS patients (11-14). Several of the opportunistie infeetions caused by herpesviruses include encephalitis, chorioretinitis, hairy leukoplakia, esophagitis, enteritis, colitis, Burkitt's lymphoma, primary CNS lymphoma, zoster, and there has even been speculation about the role of CMV in the pathogenesis of Kaposi's sareoma (15,16). Furthermore, the herpesviruses, partieularly CMV and EBV have been known to be strongly associated with immunosuppression, partieularly of cell-mediated immune functions, which further supported the hypothesis that herpesviruses may contribute to the immune defects that eharacterize AIDS.
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