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Clinical Trials for the Treatment of Sepsis, W.J. Sibbald; Jean-Louis Vincent


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Автор: W.J. Sibbald; Jean-Louis Vincent
Название:  Clinical Trials for the Treatment of Sepsis
ISBN: 9783642792267
Издательство: Springer
Классификация:




ISBN-10: 364279226X
Обложка/Формат: Paperback
Страницы: 406
Вес: 0.62 кг.
Дата издания: 22.11.2011
Серия: Update in Intensive Care and Emergency Medicine
Язык: English
Размер: 234 x 156 x 23
Основная тема: Medicine & Public Health
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Sepsis and Innovative Treatment: The Odyssey R. C. Bone The Odyssey by Homer, dates back to the 8th century, B. C. 1]. It is a great epic adventure of Odysseuss dramatic journey from Troy back home to Ithaca. Odysseus survives the ordeals of this journey and returns with new powers and insights. The study of the pathogenesis and treatment of sepsis has also been an odys- sey. I feel we will return from this odyssey with new insights and treatments. However, as with Odysseus, this will occur only after considerable struggle. In the 1980s we had a rather simplistic view of sepsis. It was a highly lethal complication caused by infection and often charac- terized by shock and multi-organ failure. Our knowledge of the inflammatory responses associated with sepsis was embryonic compared to today. The inflammatory response was often treat- ment with mega-dose corticosteroids along with fluid resuscita- tion, vasopressors and antibiotics. Because of the paucity of mul- ti-center controlled trials documenting the risk/benefit ratio of the treatment of sepsis with corticosteroids, two large multi-cen- ter controlled trials were organized to evaluate the role of corti- costeroids in sepsis 2, 3]. Because animal models showed bene- fits of corticosteroids only with pre-treatment or early treatment, a definition of sepsis was used that did not require positive cul- ture documentation or septic shock to be included in the studied population.

Sepsis

Автор: Nicholas S. Ward; Mitchell M. Levy
Название: Sepsis
ISBN: 3319484680 ISBN-13(EAN): 9783319484686
Издательство: Springer
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Цена: 93160.00 T
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Описание: This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis.

Management of Sepsis: the PIRO Approach

Автор: Jordi Rello; Emili D?az; Alejandro Rodr?guez (Eds.
Название: Management of Sepsis: the PIRO Approach
ISBN: 3642004784 ISBN-13(EAN): 9783642004780
Издательство: Springer
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Цена: 65170.00 T
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Описание: Sepsis is a very important public health problem. It is widely acknowledged that the severe inflammatory response syndrome/severe sepsis paradigm fails to stratify sepsis patients adequately. This book reviews in how sepsis should be managed on the basis of a fresh approach to staging.

Optimizing Antimicrobial Therapy of Life-threatening Infection, Sepsis and Septic Shock, An Issue of Critical Care Clinics ,27-1

Автор: Anand Kumar
Название: Optimizing Antimicrobial Therapy of Life-threatening Infection, Sepsis and Septic Shock, An Issue of Critical Care Clinics ,27-1
ISBN: 1455704318 ISBN-13(EAN): 9781455704316
Издательство: Elsevier Science
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Цена: 91370.00 T
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Описание: Features articles on: Optimizing Antimicrobial Therapy in Life-threatening infection, sepsis and septic shock; General principles of antimicrobial dosing and PK/PD; Pharmacokinetic and pharmacodynamic issues in the critically ill with severe sepsis and septic shock; Understanding antimicrobial resistance; and, Antifungal therapy.

Management of Sepsis: the PIRO Approach

Автор: Rello
Название: Management of Sepsis: the PIRO Approach
ISBN: 3642101488 ISBN-13(EAN): 9783642101489
Издательство: Springer
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Цена: 74530.00 T
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Описание: Sepsis is a very significant public health problem. This book reviews in detail how sepsis should be managed on the basis of a novel approach to staging. The book clearly explains the advantages of the PIRO approach in different settings.

Evolving Concepts in Sepsis and Septic Shock

Автор: Peter Q. Eichacker; J?r?me Pugin
Название: Evolving Concepts in Sepsis and Septic Shock
ISBN: 0792372352 ISBN-13(EAN): 9780792372356
Издательство: Springer
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Цена: 204040.00 T
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Sepsis and Organ Dysfunction

Автор: A.E. Baue; G. Berlot; A. Gullo; J.-L. Vincent
Название: Sepsis and Organ Dysfunction
ISBN: 8847000963 ISBN-13(EAN): 9788847000964
Издательство: Springer
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Цена: 81050.00 T
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Описание: Progression of the sepsis-MODS syndrome is tied to: the severity and location of the lesion; the patient`s age; the remaining functional reserve; and the presence of mediatory which may be stimulatory, inhibitory or both. This overview is aimed at anaesthesiologists and doctors.

Sepsis and Organ Dysfunction

Автор: A.E. Baue; G. Berlot; A. Gullo; J.-L. Vincent
Название: Sepsis and Organ Dysfunction
ISBN: 8847001781 ISBN-13(EAN): 9788847001787
Издательство: Springer
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Цена: 102480.00 T
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Описание: Even if in the last years more information on sepsis and new treatments has become available, mortality rate is however high. Another major problem is the consequent organ failure, which grows in a sequential way and in relation with the lesion gravity and the functional reserves of the patient.

Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery.2007

Автор: AbrahamAbraham
Название: Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery.2007
ISBN: 3540301585 ISBN-13(EAN): 9783540301585
Издательство: Springer
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Цена: 111790.00 T
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Описание: There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.

Sepsis and Organ Dysfunction

Автор: A.E. Baue; G. Berlot; A. Gullo; J.L. Vincent
Название: Sepsis and Organ Dysfunction
ISBN: 8847000521 ISBN-13(EAN): 9788847000520
Издательство: Springer
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Цена: 81050.00 T
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Описание: A Tribute to Roger Bone

Sepsis

Автор: K. Reinhart; K. Eyrich
Название: Sepsis
ISBN: 3642830854 ISBN-13(EAN): 9783642830853
Издательство: Springer
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Цена: 102480.00 T
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Описание: Despite the progress that has been made in intensive care medicine, sepsis and septic shock are still accompanied by a high mortality rate. This monograph contains contributions by well-known scientists and clinicians in the fields of hygienics, microbiology, infectious diseases, physiology, surgery and intensive care medicine.

Sepsis

Автор: Guillermo Ortiz-Ruiz; Carmelo Due?as-Castell
Название: Sepsis
ISBN: 1493973320 ISBN-13(EAN): 9781493973323
Издательство: Springer
Рейтинг:
Цена: 79190.00 T
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Описание: In addition to thoroughly revised chapters from the previous edition that covers the latest in diagnostics, therapeutics, and antimicrobials, the third edition features new chapters on the economic impact of infections and antibiotics, multi-organ failure in sepsis, and current strategies for training high-performance teams.

Sepsis Management

Автор: Jordi Rello; Jeffrey Lipman; Thiago Lisboa
Название: Sepsis Management
ISBN: 3662519402 ISBN-13(EAN): 9783662519400
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
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Описание: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.


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