Minimal Residual Disease in Acute Leukemia 1986, A. Hagenbeek; B. L?wenberg

Автор: U. Reinhold; W. Tilgen
Название: Minimal Residual Disease in Melanoma
ISBN: 364264015X ISBN-13(EAN): 9783642640155
Издательство: Springer
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Цена: 121110.00 T
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Описание: The 1st International Symposium "Minimal Residual Disease in Melanoma: Biology, Detection and Clinical Relevance of Microme- tastases", held in September 1999 in Homburg/Saar, Germany, fo- cused on recent developments in this particular area of cancer re- search.

Автор: Hiddemann
Название: Handbook of Acute Leukemia
ISBN: 3319267701 ISBN-13(EAN): 9783319267708
Издательство: Springer
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Цена: 55890.00 T
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Описание: This book provides an overview of the key developments in both acute lymphocytic leukemia and acute myeloid leukemia with a comprehensive guide to the epidemiology, pathogenesis, etiology, clinical manifestations, classification, diagnosis, and staging as well as the most recent developments in the therapeutic landscape for acute leukemia.

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
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Цена: 167700.00 T
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: B. L?wenberg; A. Hagenbeek
Название: Minimal Residual Disease in Acute Leukemia
ISBN: 9401090025 ISBN-13(EAN): 9789401090025
Издательство: Springer
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Цена: 81050.00 T
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Описание: They include the production and ap plication of monoclonal antibodies against differentiation antigens on the cell sur face, the use of pulse cytophotometry - and cell sorter techniques, the employment of cytogenetics, the development of culture techniques for selective growth of precursor cells and several others.

Автор: Michail Ignatiadis; Christos Sotiriou; Klaus Pante
Название: Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer
ISBN: 364244587X ISBN-13(EAN): 9783642445873
Издательство: Springer
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Цена: 186330.00 T
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Описание: This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.

Автор: Gianni Bonadonna; G. Mathe; S. E. Salmon
Название: Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease I
ISBN: 3642813224 ISBN-13(EAN): 9783642813221
Издательство: Springer
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Цена: 121110.00 T
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Описание: 1978 Annual Plenary Meeting of the European Organization for Treatment of Cancer, Paris, June 1978

Автор: Gianni Bonadonna; G. Mathe; S. E. Salmon
Название: Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II
ISBN: 3642813348 ISBN-13(EAN): 9783642813344
Издательство: Springer
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Цена: 121110.00 T
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Описание: 1978 Annual Plenary Meeting of the European Organization for Research on Treatment of Cancer, Paris, June 1978

Автор: Judith E. Karp
Название: Acute Myelogenous Leukemia
ISBN: 1617376752 ISBN-13(EAN): 9781617376757
Издательство: Springer
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Цена: 231990.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a timely compilation of new concepts in the molecular pathogenesis and molecular therapy of acute myelogenous leukemia (AML). The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities.

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493913921 ISBN-13(EAN): 9781493913923
Издательство: Springer
Рейтинг:
Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: L.O. Baker; Frederick A. Valeriote; Voravit Ratana
Название: Biology and Therapy of Acute Leukemia
ISBN: 0898387280 ISBN-13(EAN): 9780898387285
Издательство: Springer
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Цена: 204040.00 T
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Описание: Proceedings of the Seventeenth Annual Detroit Cancer Symposium, held in Detroit, Michigan, April 12-13, 1984

Автор: Abla
Название: Acute Promyelocytic Leukemia
ISBN: 3319642561 ISBN-13(EAN): 9783319642567
Издательство: Springer
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Цена: 111790.00 T
Наличие на складе: Поставка под заказ.
Описание: This book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on secondary APL and therapy, late effects, rare presentations such as APL in the elderly and during pregnancy, and rare APL variants that may represent therapeutic challenges.Written by top experts in the field, Acute Promyelocytic Leukemia: A Clinical Guide is a valuable resource for clinicians and researchers who treat and investigate this disease in children and adults.

Автор: Paolo Fortina; Eric Londin; Jason Y. Park; Larry J
Название: Acute Myeloid Leukemia
ISBN: 1493971409 ISBN-13(EAN): 9781493971404
Издательство: Springer
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Цена: 130430.00 T
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Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.