Автор: Matthew M. Hayward Название: Lead-Seeking Approaches ISBN: 364226106X ISBN-13(EAN): 9783642261060 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery.
Автор: Carlos Castillo-Chavez; Simon A. Levin; Christine Название: Mathematical Approaches to Problems in Resource Management and Epidemiology ISBN: 3540518207 ISBN-13(EAN): 9783540518204 Издательство: Springer Рейтинг: Цена: 74490.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Underlying virtually all of these studies are models of population growth, from individual cells to large vertebrates. In Part I of this volume, Michael Shuler describes computer models of individual cells and cell populations, and Frank Hoppensteadt discusses the synchronization of bacterial culture growth.
Автор: Enrique Santamar?a; Joaqu?n Fern?ndez-Irigoyen Название: Current Proteomic Approaches Applied to Brain Function ISBN: 1493971182 ISBN-13(EAN): 9781493971183 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Preface to the Series Preface Table of Contents Contributing Authors
PART I Introduction
1. Brain Proteomics: Decoding Neuroproteomes using Mass-Spectrometry Joaquнn Fernбndez-Irigoyen and Enrique Santamarнa
PART II Labeling Methods in Neuroproteomics
2. Applications of Amine-Reactive Tandem Mass Tags (TMT) in Human Neuroproteomics Linnйa Lagerstedt, Leire Azurmendi, and Jean-Charles Sanchez
3. Application of Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) to Monitor Olfactory Proteomes during Alzheimer s Disease Progression Andrea Gonzбlez-Morales, Mercedes Lachйn-Montes, Marнa Ibaсez-Vea, Enrique Santamarнa, and Joaquнn Fernбndez-Irigoyen
4. Protein Microarrays in Neurodegenerative Diseases Pablo San Segundo-Acosta, Marнa Garranzo-Asensio, Ana Montero-Calle, Carmen Oeo-Santos, Mayte Villalba, Ana Guzmбn-Arбnguez, and Rodrigo Barderas
PART III Label-Free Methods in Neuroproteomics
5. Comprehensive Shotgun Proteomic Analyses of Oligodendrocytes using Ion Mobility and Data Independent Acquisition Juliana S. Cassoli and Daniel Martins-de-Souza
6. Non-Targeted Brain Lipidomics Profiling Performed by UPLC-ESI-qTOF-MS/MS Alba Naudн, Rosanna Cabrй, Mariona Jovй, and Reinald Pamplona
7. Methods for Human Olfactory Bulb-Tissue Studies using Peptide/Protein MALDI-TOF Imaging Mass Spectrometry (MALDI-IMS) Ibon Iloro, Joaquнn Fernбndez-Irigoyen, Iraide Escobes, Mikel Azkargorta, Enrique Santamarнa, Felix Elortza
8. Neuroproteomics using Short GeLC-SWATH: From the Evaluation of Proteome Changes to the Clarification of Protein Function Sandra I. Anjo, Cбtia Santa, Susana C. Saraiva, Karolina Freitas, Faraj Barah, Bruno Carreira, Inкs Araъjo, and Bruno Manadas
PART IV Mass Spectrometry-based Neuroproteomics to Analyze Post-Translational Modificiations
9. Analysis of Brain Phosphoproteome using Titanium Dioxide Enrichment and High Resolution LC-MS/MS Jeffrey M. Sifford, Haiyan Tan, Hong Wang, and Junmin Peng
10. N-Glycomics and N-Glycoproteomics of Human Cerebrospinal Fluid Sophie Cholet, Arnaud Goyallon, Christophe Junot, and Franзois Fenaille
11. In Vivo Strategies to Isolate and Characterize the Neuronal Ubiquitinated Proteome Juanma Ramнrez, Nagore Elu, Aitor Martinez, Benoit Lectez, and Ugo Mayor
12. Characterization of the Phosphoproteome and Sialoproteome in Brain Tissues by Mass Spectrometry Marнa Ibaсez-Vea, Stefan J. Kempf, and Martin R. Larsen
13. Proteomic Analysis of SUMOylation in the Post-Ischemic Brain J. Will Thompson, Meng Jiang, and Wei Yang
14. S-Nitrosylation in Alzheimer s Disease using Oxidized Cysteine-Selective cPILOT Ryan R. Dyer, Liqing Gu, and Renг A.S. Robinson
PART V Subcellular Neuroproteomics
15. Proteomic Analysis of Extracellular Vesicles in Neurological Diseases Matнas Sбenz-Cuesta, Enrique Santamarнa, Joaquнn Fernбndez-Irigoyen, and David Otaegui
16. Quantitative In-Depth Profiling of the Postsynaptic Density Proteome to Understand the Molecular Mechanisms Governing Synaptic Physiology and Pathology Rita Reig-Viader and Alex Bayйs
17. Nuclear Proteomics for Exploring MK-801 Treated Oligodendrocytes to Better Understand Schizophrenia Aline G. Santana, Giuliana S. Zuccoli, Verфnica Saia-Cereda, Juliana S. Cassoli, and Daniel Martins-de-Souza
18. Localized Proteomics of Individual Neurons Isolated from Formalin-Fixed, Para
Автор: B. Schierwater; B. Streit; G.P. Wagner; R. DeSalle Название: Molecular Ecology and Evolution: Approaches and Applications ISBN: 3034875290 ISBN-13(EAN): 9783034875295 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: M. Matthies; H. Malchow; J. Kriz Название: Integrative Systems Approaches to Natural and Social Dynamics ISBN: 3642625266 ISBN-13(EAN): 9783642625268 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Elva Escobar-Briones; Fernando Alvarez Название: Modern Approaches to the Study of Crustacea ISBN: 1461352282 ISBN-13(EAN): 9781461352280 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: When teach my undergraduate course in these animals belong together, and we nowlearn that Crustacea at the University of Copenhagen always they may even encompass the speciose insects. With or tell my students: " Now, if on reading through the without insects the Crustacea are therefore unquestion- chapter on Crustacea you wonder, what could pos- ably one of the most important animal groups. Is this sibly be said in common about these animals, you why we study them? I think not. Our fascination with havegot it exactly right Indeed, there is next to noth- Crustacea is even deeper rooted and not easily ana- ing that unite them". Crustaceans range in size from lyzed. But one thing is important to me in this context. much below millimeter size to the giant king crabs; As Ibrowse through aU the papers in this book it brings in morphology from the almost stereotyped segment up the memoryofthe highlyrewarding Summer Meet- repetition ofthe Remipedia to animals with a highly The Crustacean Society held in 2000 in Puerto ing of diverse array of appendages such as the Decapoda; Vallarta, Mexico, where I had the privilege to serve as in life form from suspension feeding anostracans to its president.
Автор: Riccardo Brambilla Название: Viral Vector Approaches in Neurobiology and Brain Diseases ISBN: 1493959433 ISBN-13(EAN): 9781493959433 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers key aspects related to the use of viral vectors in neurobiology, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain diseases.
Автор: Lars H?kanson Название: Modelling radiocesium in lakes and coastal areas — new approaches for ecosystem modellers ISBN: 0792362454 ISBN-13(EAN): 9780792362456 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Over the years, there has been a `revolution` in ecosystem modelling. This book describes a new generation of useful models that predict as well as one can measure - if one measures well. It is of interest to: students in radioecology, geosciences and biology; environmental engineers; consultants; and administrators and scientists.
Автор: Toru Ohira; Tohru Uzawa Название: Mathematical Approaches to Biological Systems ISBN: 4431554432 ISBN-13(EAN): 9784431554431 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents the most recent mathematical approaches to the growing research area of networks, oscillations, and collective motions in the context of biological systems. Bringing together the results of multiple studies of different biological systems, this book sheds light on the relations among these research themes. Included in this book are the following topics: feedback systems with time delay and threshold of sensing (dead zone), robustness of biological networks from the point of view of dynamical systems, the hardware-oriented neuron modeling approach, a universal mechanism governing the entrainment limit under weak forcing, the robustness mechanism of open complex systems, situation-dependent switching of the cues primarily relied on by foraging ants, and group chase and escape. Research on different biological systems is presented together, not separated by specializations or by model systems. Therefore, the book provides diverse perspectives at the forefront of current mathematical research on biological systems, especially focused on networks, oscillations, and collective motions. This work is aimed at advanced undergraduate, graduate, and postdoctoral students, as well as scientists and engineers. It will also be of great use for professionals in industries and service sectors owing to the applicability of topics such as networks and synchronizations.
Автор: Jianfeng Zhang Название: Coastal Saline Soil Rehabilitation and Utilization Based on Forestry Approaches in China ISBN: 3642399142 ISBN-13(EAN): 9783642399145 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The most recent advances in research on coastal saline soil rehabilitation and utilization based on forestry approach are discussed. The forestry approach is emphasized rather than physical or engineering measures to ameliorate saline soils, which is significant for coastal environmental improvement and land resources expansion.
Автор: Johan Bouma; A. Kuyvenhoven; B.A.M Bouman; J.C. Lu Название: Eco-regional approaches for sustainable land use and food production ISBN: 9401040583 ISBN-13(EAN): 9789401040587 Издательство: Springer Рейтинг: Цена: 243800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of a Symposium on Eco-Regional Approaches in Agricultural Research, 12--16 December 1994, ISNAR, The Hague
Автор: Andrew Woodhall; Gabriel Garmendia da Trindade Название: Ethical and Political Approaches to Nonhuman Animal Issues ISBN: 3319545485 ISBN-13(EAN): 9783319545486 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book offers ethical and political approaches to issues that nonhuman animals face. Presenting work by theorists and activists, insights are offered from both ethics and politics that impact theory and practice and offer essential considerations for those engaging in interspecies ethics within the political turn era.
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