New Toxicology for Old, P.L. Chambers; C.M. Chambers

Автор: Ward Kevin R., Matejtschuk Paul
Название: Lyophilization of Pharmaceuticals and Biologicals: New Technologies and Approaches
ISBN: 1493989278 ISBN-13(EAN): 9781493989270
Издательство: Springer
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Описание: This detailed volume brings together leading practitioners in the freeze-drying community to address recent progress, not only in new analytical tools and applications of the data derived in cycle design but also in the manufacturing of lyophilized products in the healthcare sector - whether these be therapeutics, vaccines or diagnostic products - and indeed the equipment to deliver this scale of freeze-drying. Areas of focus include analytical and formulation issues, process monitoring and control, as well as post-lyophilization analysis. Written for the Methods in Pharmacology and Toxicology series, chapters include the type of expert advice that leads to superior results in the lab.

Authoritative and practical, Lyophilization of Pharmaceuticals and Biologicals: New Technologies and Approaches serves as an ideal guide for researchers working in or just seeking an update on this rapidly changing field.

Автор: David Kritchevky
Название: Lipids, Lipoproteins, and Drugs
ISBN: 1468432605 ISBN-13(EAN): 9781468432602
Издательство: Springer
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Цена: 139310.00 T
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Описание: The First International Symposium on Drugs Affecting Lipid Metabolism was held in Milan in 1960. In the succeeding symposia, as in the first, new data and new ideas emerged which stimulated further research in the field. The present volume comprises the proceedings of the Fifth Symposium. In the area of lipoproteins, we have progressed from descriptions of their chemistry to dis- cus sion of their physiology and of their control of cholesterol metabolism at the cellular level. Workshop sessions explored thrombosis as affected by drugs, risk factors other than diet, animal models for atherosclerosis research and the organization of lipid clinics and clinical trials. All these topics represent advances in knowledge over the last decade. In the area of drugs a number of new compounds were introduced, many of them offer- ing new structural concepts for hypocholesteremic activity. We expect that the next Symposium will offer as many new hypotheses and avenues of approach as did this one. We gratefully acknowledge the assistance of Dr. Sergio Gorini and the Lorenzini Foundation and the contributions of Drs. Cesare Sirtori and Remo Fumagalli all of which helped to assure the success of this Symposium. We also wish to thank Miss Jane T. Kolimaga for her assistance in the preparation of this volume. David Kritchevsky Rodol o Paoletti William L. Holme s vii CONTENTS Opening Remarks. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 W. L. Holmes CHEMISTRY AND PHYSIOLOGY OF LIPOPROTEINS The Interaction of Apolipoprotein-Alanine (ApoC-III) with Lipids: Study of Structural Features Required for Binding. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Автор: N.E. Fusenig; H. Graf
Название: Cell Culture in Pharmaceutical Research
ISBN: 3662030136 ISBN-13(EAN): 9783662030134
Издательство: Springer
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Описание: Cell biology has made an appreciable impact on the evaluation of physiological and pathophysiological processes leading to a more detailed understanding of the signaling mechanisms by which cells communicate in vivo and in vitro and modify adaptively.

Автор: W. Lowry
Название: Forensic Toxicology
ISBN: 1468434462 ISBN-13(EAN): 9781468434460
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Описание: With the rapid spread of drug use and abuse in this country over the last decade, events relating to drugs have become increasingly prominent in the court of law as well as in society in general.

Автор: Leslie L. Iversen; Susan D. Iversen; Solomon H. Sn
Название: Handbook of Psychopharmacology
ISBN: 1461334543 ISBN-13(EAN): 9781461334545
Издательство: Springer
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Описание: Volume 15 of Handbook of Psychopharmacology represents the first of a new series of volumes whose aim is to bring earlier sections of the work up to date by describing the latest developments in the field.

Автор: O. Pelkonen; A. Baumann; A. Reichel
Название: Pharmacokinetic Challenges in Drug Discovery
ISBN: 3662043858 ISBN-13(EAN): 9783662043851
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Описание: The Pharmaceutical industry is therefore focussing on ways to reduce attrition by addressing frequent reasons for clinical drug failures very early in the drug discovery process.

Автор: Akira Kitabatake; Ichiro Sakuma
Название: Recent Advances in Nitric Oxide Research
ISBN: 4431680101 ISBN-13(EAN): 9784431680109
Издательство: Springer
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Автор: Hanns M?hler
Название: Pharmacology of GABA and Glycine Neurotransmission
ISBN: 3642631916 ISBN-13(EAN): 9783642631917
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Описание: With contributions by numerous experts

Автор: K. D. Rainsford; G.P Velo
Название: Side-Effects of Anti-Inflammatory Drugs 3
ISBN: 9401053251 ISBN-13(EAN): 9789401053259
Издательство: Springer
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Описание: The contents of this book represent papers which were presented at the Third International Meeting on "Side-Effects of Anti-Inflammatory and Analgesic Drugs" which was held under the auspices of the University of Verona, Institute of Pharmacology in Verona on 8-11 May 1991.

Автор: Allan R. Ronald; Donald Low
Название: Fluoroquinolone Antibiotics
ISBN: 3034894376 ISBN-13(EAN): 9783034894371
Издательство: Springer
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Автор: P.K. Gessner
Название: Disulfiram and its Metabolite, Diethyldithiocarbamate
ISBN: 9401050287 ISBN-13(EAN): 9789401050289
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Автор: Eric Ertel; Th?ophile Godfraind
Название: Calcium Channel Blockers
ISBN: 3034895992 ISBN-13(EAN): 9783034895996
Издательство: Springer
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Описание: The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects, and perspectives.