Gene Transfer and Expression, Michael Kriegler

Автор: J.K. Pollak; J.W. Lee
Название: The Biochemistry of Gene Expression in Higher Organisms
ISBN: 9401025525 ISBN-13(EAN): 9789401025522
Издательство: Springer
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Цена: 148020.00 T
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Описание: Proceedings of a Symposium Sponsored by the International Union of Biochemistry, the Australian Academy of Science and the Australian Biochemical Society

Автор: Charles E. Bullerwell
Название: Organelle Genetics
ISBN: 3642431720 ISBN-13(EAN): 9783642431722
Издательство: Springer
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Цена: 156720.00 T
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Описание: Organelle Genetics explores the forces that have shaped the evolution of organelle genomes, and the expression of the genes they encode, following their divergence from bacterial ancestors. The text focuses on the current techniques used to study the evolution of organelle genomes and gene expression.

Автор: J. Ilan
Название: Translational Regulation of Gene Expression 2
ISBN: 1461362547 ISBN-13(EAN): 9781461362548
Издательство: Springer
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Цена: 46570.00 T
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Описание: This book, which results from the dramatic increase in interest in the control mechanism employed in gene expression and the importance of the regulated proteins, presents new information not covered in Translational Regulation of Gene Expression, which was published in 1987.

Автор: Heinz Rupp; Bernhard Maisch
Название: Control of Gene Expression by Catecholamines and the Renin-Angiotensin System
ISBN: 146136955X ISBN-13(EAN): 9781461369554
Издательство: Springer
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Цена: 139750.00 T
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Описание: The special issue of Molecular and Cellular Biochemistry focuses on `Control of Gene Expression by Catecholamines and the Renin-Angiotensin System` in health and disease. This focused issue is organized into chapters concentrating on catecholamines, angiotensin II, and the interaction between catecholamines and angiotensin II.

Автор: Lucy W. Barrett; Sue Fletcher; Steve D. Wilton
Название: Untranslated Gene Regions and Other Non-coding Elements
ISBN: 3034806787 ISBN-13(EAN): 9783034806787
Издательство: Springer
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Цена: 65290.00 T
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Описание: There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes.

Автор: Wu
Название: Amino Acids in Nutrition and Health
ISBN: 3030741826 ISBN-13(EAN): 9783030741822
Издательство: Springer
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Цена: 186330.00 T
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Описание: This book explains about amino acids (AAs) which are not only building blocks of protein, but are also signaling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular-weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds, and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole-body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health, and well-being of individuals.

Автор: Gary H. Perdew; Jack P. Vanden Heuvel; Jeffrey M.
Название: Regulation of Gene Expression
ISBN: 1627038086 ISBN-13(EAN): 9781627038089
Издательство: Springer
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Цена: 139750.00 T
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Описание: The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in specific areas of molecular biology and regulation of gene expression. However, we have noticed a lack of books, especially textbooks, that provide an overview of the rationale and general experimental approaches used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. For example, it has been difficult to find appropriate texts that examine specific experimental goals, such as proving that an increased level of mRNA for a given gene is attributable to an increase in transcription rates. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel. Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State University. For more details about this class, please visit http://moltox. cas. psu. edu and select “Courses. ” The goal for our work is to provide an overview of the various methods and approaches to characterize possible mechanisms of gene regulation. Further, we have attempted to provide a framework for students to develop an understanding of how to determine the various mechanisms that lead to altered activity of a specific protein within a cell.

Автор: Robert Goldberger
Название: Biological Regulation and Development
ISBN: 1468434195 ISBN-13(EAN): 9781468434194
Издательство: Springer
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Цена: 46570.00 T
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Описание: We thought it might be more interesting and more instructive-for both author and reader-to avoid reviewing topics that anyone scientist might work on, but instead to review the various parts of what many different scientists work on.

Автор: Rodrick Wallace; Deborah Wallace
Название: Gene Expression and Its Discontents
ISBN: 148998531X ISBN-13(EAN): 9781489985316
Издательство: Springer
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Цена: 204040.00 T
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Описание: This volume examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner.

Автор: Ming-Ming Zhou
Название: Histone Recognition
ISBN: 3319181017 ISBN-13(EAN): 9783319181011
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.

Автор: Rodrick Wallace; Deborah Wallace
Название: Gene Expression and Its Discontents
ISBN: 3319480774 ISBN-13(EAN): 9783319480770
Издательство: Springer
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Цена: 144410.00 T
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Описание: This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the population level in the face of persistent individual and community stress. Drugs powerful enough to affect deleterious epigenetic programming will likely have side effects leading to shortened lifespan. Addressing chronic conditions and developmental disorders requires significant large-scale changes in public policy and resource allocation.

Автор: Mei-Ling Ting Lee
Название: Analysis of Microarray Gene Expression Data
ISBN: 1475788231 ISBN-13(EAN): 9781475788235
Издательство: Springer
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Цена: 139750.00 T
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Описание: After genomic sequencing, microarray technology has emerged as a widely used platform for genomic studies in the life sciences. With the abundance of data produced from microarray studies, however, the ultimate impact of the studies on biology will depend heavily on data mining and statistical analysis.