Quantitative Aspects of Chemical Pharmacology, R.B. Barlow

Автор: Golan, David E.
Название: Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy
ISBN: 1496320573 ISBN-13(EAN): 9781496320575
Издательство: Lippincott Williams & Wilkins
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Цена: 59670.00 T
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Описание: Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 4th Edition, offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development.

Автор: J. Clemmesen; A. Waring; D.M. Conning; D. Henschle
Название: Quantitative Aspects of Risk Assessment in Chemical Carcinogenesis
ISBN: 3540095845 ISBN-13(EAN): 9783540095842
Издательство: Springer
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Цена: 121110.00 T
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Описание: N-nitroso-compounds form an important class of carcinogenic chemicals which may be of environmental importance (Druckrey et al., 1967; Magee et al., 1976; IARC, 1978). The mechanism by which these carcinogens initiate neoplastic growth is not well understood but there is substantial evidence favoring the hypothesis that the simple dialkylnitrosamines and alkylnitrosamides act by means of their conversion to al- kylating agents. Alkylating species are generated from the nitrosamines by metabolic activation and from the nitrosamides by chemical decomposition at physiological pH. It is widely believed that DNA is the critical alkylation target. Alkylation takes place at at least 12 sites within the DNA molecule (Lawley, 1976; Singer, 1976; Pegg, 1977a). Al- though alkylation at the 7-position of guanine is the most extensive reaction with the DNA bases and provides a reliable measurement of the degree of interaction with the carcinogen (Swann and Magee, 1968, 1971), recent experiments have suggested that alkylation of oxygen atoms may be the critical reaction (Goth and Rajewsky, 1974; Margison and Kleihues, 1975; Nicoll et aI., 1975; Pegg, 1977a). These laboratories have observed a correlation between the production and persistence of 06-alkyl- guanine and the occurrence oftumors in a variety of organs of rodents exposed to N-ni- troso-carcinogens. It has, therefore, been suggested that the ability of tissues to catalyze the removal of 06-alkylguanine from DNA may provide a protective mechanism against carcinogenesis.

Автор: Golan
Название: Principles of pharmacology 3ed.
ISBN: 1451118058 ISBN-13(EAN): 9781451118056
Издательство: Lippincott Williams & Wilkins
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Цена: 44530.00 T
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Описание: Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, Third Edition, is a primary textbook for a first course in pharmacology. It offers an integrated mechanism-based and systems-based approach, incorporating the cell biology, biochem

Автор: Raffa, Robert
Название: Netter`s Illustrated Pharmacology Updated Edition
ISBN: 0323220916 ISBN-13(EAN): 9780323220910
Издательство: Elsevier Science
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Цена: 49390.00 T
Наличие на складе: Нет в наличии.
Описание: Offers a visual approach to understanding both the basic science and clinical applications of pharmacology. Designed to be compatible and used in conjunction with other pharmacology resources, this book includes a presentation of the pharmacodynamic relationship between drugs and the human body.

Автор: Peck
Название: Pharmacology for Anaesthesia and Intensive Care Cambridge University Press., Paperback, 2014
ISBN: 1107657261 ISBN-13(EAN): 9781107657267
Издательство: Cambridge Academ
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Цена: 63350.00 T
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Описание: The fourth edition of this market-leading anaesthetic book has been fully updated to include novel oral anticoagulants and neuromuscular reversal agents. Numerous other sections have been expanded or updated to reflect new research and current best practice, and the antibiotics chapter now includes information about commonly encountered pathogens and the drugs used to target them. Basic pharmacological principles, vital to understanding the effects of individual drugs, are dealt with methodically, and the essential physiology is described alongside the relevant pharmacology. This has become the core pharmacology book for the FRCA, covering all the relevant kinetics and dynamics in a compact and easy to navigate format, including clear diagrams and tables. This is an ideal aid to study and practice for junior and trainee anaesthetists. Theatre practitioners, ICU nurses and physicians working in areas that demand a solid foundation of pharmacological knowledge will also find this an invaluable resource.

Автор: Lemont B. Kier
Название: Molecular Orbital Studies in Chemical Pharmacology
ISBN: 354004972X ISBN-13(EAN): 9783540049722
Издательство: Springer
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Цена: 102480.00 T
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Описание: The lecturers at this symposium, all interested in molecular orbital theory, have backgrounds in pharmacology, physical chemistry, theoretical chemistry, bio- chemistry and medicinal chemistry.

Автор: Axelsen Paul H.
Название: Essentials of Antimicrobial Pharmacology / A Guide to Fundamentals for Practice
ISBN: 0896037606 ISBN-13(EAN): 9780896037601
Издательство: Springer
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Цена: 104480.00 T
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Описание: Paul H. Axelsen concisely summarizes all the essential medical data concerning the leading antimicrobials used in fighting infectious diseases and clearly illustrates their mechanisms of action. The agents described range from antibacterial and antifungal to antiparasitic and antiviral agents, and include immunomodulators and immunizing agents. For each drug discussed, the book allows rapid access to the essential facts concerning its structure and mechanism of action, the spectrum of its activity, its pharmacokinetics, its adverse effects, and its resistance. This book provides medical students, physicians, and allied health professionals with rapid access to the core principles of antimicrobial pharmacology, and a foundation for decisions about the use of antimicrobials in daily practice.

Автор: Domenico Spina
Название: The Flesh and Bones of Medical Pharmacology
ISBN: 0723433534 ISBN-13(EAN): 9780723433538
Издательство: Elsevier Science
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Цена: 25810.00 T
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Описание: Presents an account of pharmacology, covering various key concepts you need.

Автор: Rosenfeld
Название: BRS Pharmacology 5e
ISBN: 0781789133 ISBN-13(EAN): 9780781789134
Издательство: Lippincott Williams & Wilkins
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Цена: 30310.00 T
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Описание: A review of medical pharmacology designed for medical students, dental students, and those in the health care professions. It intends to help students prepare for the USMLE Step 1 and similar licensing examinations. It covers chapters that present specific drugs and discuss their general properties, mechanism of action and pharmacologic effects.

Автор: Tozer
Название: Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy
ISBN: 0781751497 ISBN-13(EAN): 9780781751490
Издательство: Lippincott Williams & Wilkins
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Цена: 49190.00 T
Наличие на складе: Поставка под заказ.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Автор: Katzung
Название: Basic and Clinical Pharmacology. 13 ed IE
ISBN: 1259252906 ISBN-13(EAN): 9781259252907
Издательство: McGraw-Hill
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Цена: 37180.00 T
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Описание: The most up-to-date, comprehensive, and authoritative pharmacology text in health medicineOrganized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, 13e covers the important concepts students need to know about the science of pharmacology and its application to clinical practice.

Автор: Rosenfeld Gary C
Название: BRS Pharmacology. 6 ed.
ISBN: 1451175353 ISBN-13(EAN): 9781451175356
Издательство: Lippincott Williams & Wilkins
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Цена: 43410.00 T
Наличие на складе: Невозможна поставка.
Описание: BRS Pharmacology is designed for medical students, dental students, and other students preparing to enter the health care professions. It is intended primarily to help students prepare for licensing examinations, such as the USMLE, but can be used for course review or as a supplementary text. This book presents succint descriptions of how drugs act on the major body systems, providing readers with vital information without overloading them with extraneous details. Written with a body systems approach, the book begins with a chapter devoted to the general principles of drug mechanisms, and continues with chapters that detail how drugs act on the major body systems. Other chapters discuss numerous popular drugs, like autocoids, ergots, anti-inflammatory drugs, and immunosuppresive agents. Readers will also learn about drugs used to treat anemia, disorders of hemostatis, infectious diseases, and cancer. Additionally, the text covers pharmacological principles associated with toxicology.