Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology, Mohammad Resa Nowrousian

Автор: W.N. Drohan; Leon W. Hoyer
Название: Recombinant Technology in Hemostasis and Thrombosis
ISBN: 1461366445 ISBN-13(EAN): 9781461366447
Издательство: Springer
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Цена: 46570.00 T
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Описание: The speakers described the essential features of the genes responsible for key plasma proteins important in hemostasis, including procoagulant Factors VIII and IX and anticoagulant proteins, Antithrombin III and Protein C.

Автор: Wolfgang Jelkmann; Mary Cotes; Andreas J. Gross
Название: Erythropoietin
ISBN: 3642837476 ISBN-13(EAN): 9783642837470
Издательство: Springer
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Цена: 93160.00 T
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Описание: Recent developments in recombinant DNA technology have led to the large-scale production of human erythropoietin and to the demonstration that it is effective in the treatment of renal and possibly some other anaemias. This has lent a new impetus to studies of the pathophysiology and pharmacology of the hormone which is reflected in this report of the proceedings of a meeting held in Liibeck in June 1988. In 15 papers, all from European centres, the broad topics covered are erythropoietin's physiology and chemistry, the patho- physiology of erythropoiesis and the use of erythropoietin in the treatment of anaemia. Several of the papers include up-to-date reviews of the literature. The field is now expanding rapidly, and this volume, though not comprehensive, usefully points up many areas of recent understanding as well as others of continuing un- certainty. Overall, it contains material likely to be of interest to biochemists and experimental haematologists as well as to phar- macologists, clinical haematologists and nephrologists.

Автор: T. Kenakin; J. A. Angus
Название: The Pharmacology of Functional, Biochemical, and Recombinant Receptor Systems
ISBN: 3642630286 ISBN-13(EAN): 9783642630286
Издательство: Springer
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Цена: 121890.00 T
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Описание: With contributions by numerous experts

Автор: J. Lindenmann; W.-D. Schleuning
Название: Interferon: The Dawn of Recombinant Protein Drugs
ISBN: 3662037890 ISBN-13(EAN): 9783662037898
Издательство: Springer
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Цена: 113190.00 T
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Описание: Forty years of Interferon I wish to dedicate this short introduction to the memory of Alick Isaacs (1921-1967), and to that of Sir Christopher Andrewes (1896-1988). He was struck by the following observation: if a suitable chicken broth was inoculated with the bacterium, the organism grew profusely and the liquid became tur- bid.

Автор: Horst Pagel; Christoph Weiss; Wolfgang Jelkmann
Название: Pathophysiology and Pharmacology of Erythropoietin
ISBN: 3642770762 ISBN-13(EAN): 9783642770760
Издательство: Springer
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Цена: 139310.00 T
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Описание: I am honored to be invited to prepare a foreword for the proceedings of the Second International Lubeck Conference on Erythropoietin (Epo). I congratulate Wolfgang Jelkmann, Horst Pagel and Christoph Weiss for their organization of an excellent program for this conference which updated all of us on the advances made in erythropoietin research during the past few years since the first conference in June of 1988. I am sure that Professor Paul Carnot, had he been present at this conference, would be very pleased and proud of the advances made in the field of erythropoietin since his and Madame DeFlandre's seminal finding in 1906 (1) that rabbits produced a humoral substance following bleeding which controls red blood cell production. The reports by Hjort in 1936 (2) and by Erslev in 1953 (3) that large volumes of plasma or serum from rabbits following a bleeding stimulus, when injected into normal donor rabbits, produced a reticulocytosis, were very significant in confirming the existence of a humoral factor which controls erythropoiesis. Reissmann's parabiotic rat experiments in 1950 (4) reawakened interest in erythropoietin when he proved that hypoxia stimulated the production of a factor which regulates red cell produc- tion. The studies of several investigators such as Jacobson et al. (5), Fisher and Birdwell (6), Kuratowska et al. (7) and Nathan et al.

Автор: P. Buckel
Название: Recombinant Protein Drugs
ISBN: 3034895275 ISBN-13(EAN): 9783034895279
Издательство: Springer
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Цена: 139750.00 T
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Описание: Recombinant protein drugs are intimately associated with the impressive success story of the Biotech Industry during the past thirty years, some of them belonging to the most successful pharmaceutical products.

Автор: Martin Welschof; J?rgen Krauss
Название: Recombinant Antibodies for Cancer Therapy
ISBN: 1617372501 ISBN-13(EAN): 9781617372506
Издательство: Springer
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Цена: 177010.00 T
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Описание: Since the advent of hybridoma technology more than two decades ago, numerous antibodies have entered the clinical setting as potent therapeutic agents. The purpose of Recombinant Antibodies for Cancer Therapy is to present a collection of detailed protocols in recombinant antibody technology.