Systems Biology of Tuberculosis, Johnjoe McFadden; Dany J.V. Beste; Andrzej M. Kier
Название: Color atlas of comparative pathology of pulmonary tuberculosis ISBN: 1439835276 ISBN-13(EAN): 9781439835272 Издательство: Taylor&Francis Рейтинг: Цена: 137810.00 T Наличие на складе: Невозможна поставка. Описание: A pictorial histopathology atlas that features annotations on tuberculosis. It covers the manifestations of induced or acquired pulmonary tuberculosis in one of six animal species (models) - human, non-human primate, rabbit, guinea pig, rat, and mouse. It also provides low, medium, and high power microscopy views of lung tissue.
Until about 10 years ago, the general view in the field was that Mycobacterium tuberculosis, the causative agent of human tuberculosis was a "clone" with insufficient natural sequence variation between clinical strains to be considered biologically and epidemiologically "relevant." This view has now changed quite dramatically thanks to the -omics revolution, particularly the advent of next generation DNA sequencing. Large-scale comparative genomic studies over the last few years have revealed that M. tuberculosis clinical strains are more genetically diverse than appreciated previously. Moreover, an increasing number of experimental and epidemiological studies are showing that this genetic diversity also translates into important phenotypic variation. Taken together, these findings have led to a paradigm shift, such that currently phylogenetic diversity among M. tuberculosis clinical strains is being considered in the development of new tools to combat tuberculosis. The purpose of this book is to bring together a series of contributions from some of the most influential groups working on various aspects of M. tuberculosis diversity, and which through their work have contributed to the this paradigm shift. This includes authors focusing on the evolution of M. tuberculosis in relation to other members of the M. tuberculosis complex adapted to animals, the co-evolution between M. tuberculosis and humans, the phenotypic consequences of strains diversity both from an experimental and epidemiological point of view, the ecology and evolution of drug resistant tuberculosis, the diversity and evolution of the BCG vaccine strains, and the use of mathematical modelling to study strain diversity and drug resistance in human tuberculosis. No such book has ever been published, and given the paradigm shift described above, this book will be a valuable resource both for established researchers as well as new scientists, clinicians and public health officials joining the growing field of tuberculosis research.
Автор: Jean Pieters; John D. McKinney Название: Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism ISBN: 3662521423 ISBN-13(EAN): 9783662521427 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions from an interdisciplinary team of recognized experts, this illustrated volume reviews the diverse mechanisms-genetic, metabolic, and molecular-that give M. tuberculosis its antibiotic-resistant virulence and allow it to evade immune systems.
Автор: Jean Pieters; John D. McKinney Название: Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism ISBN: 3642402313 ISBN-13(EAN): 9783642402319 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions from an interdisciplinary team of recognized experts, this illustrated volume reviews the diverse mechanisms-genetic, metabolic, and molecular-that give M. tuberculosis its antibiotic-resistant virulence and allow it to evade immune systems.
Автор: Ekaterina Kulchavenya Название: Urogenital Tuberculosis: Epidemiology, Diagnosis, Therapy ISBN: 3319346024 ISBN-13(EAN): 9783319346021 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book approaches the classification, pathogenesis, diagnostic, therapy and surgery for kidney tuberculosis as well as male genital tuberculosis. The reader will find recent data on epidemiology, many interesting history cases with illustrations and new methods for the identification of Mycobacterium tuberculosis.
Автор: Mauro Bendinelli; Herman Friedman Название: Mycobacterium tuberculosis ISBN: 146845420X ISBN-13(EAN): 9781468454208 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Tuberculosis once again occupies a special position in the areas of infec- tious diseases and microbiology. Koch`s postulates were developed with tuberculosis in mind and became a focal point for many advances in microbiology and medicine.
Автор: Thomas M. Shinnick Название: Tuberculosis ISBN: 3642801684 ISBN-13(EAN): 9783642801686 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Similarly, Austria experienced a 5% increase in tuberculosis cases from 1987 to 1991, Ireland a 9% increase from 1988 to 1991, Denmark a 20% increase from 1987 to 1992, and Italy a 27% increase from 1988 to 1992.
Автор: Bethany Gwen Elkington; Djaja Djendoel Soejarto; K Название: Ethnobotany of Tuberculosis in Laos ISBN: 3319106554 ISBN-13(EAN): 9783319106557 Издательство: Springer Рейтинг: Цена: 51230.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book highlights the common ground between biomedicine and traditional healing. Because of the destruction of forests, the degradation of old palm leaf manuscripts, and decreasing interest in traditional medicine by younger generations, it is becoming more and more important to record medicinal plant knowledge before it is lost. This research provides written and photographic documentation of some of the medicinal plant knowledge held by the people of Laos. Translating and validating some of the power of traditional medicine used in Laos into biomedical terms through laboratory analyses may serve to demonstrate its importance in a global language. In this text, the translational research was performed through in vitro laboratory analyses of select plant species with a history to treat symptoms of TB. The processes of plant collection, extraction, biological assays, and isolation/elucidation are also described and detailed in the Biochemical Validation section. The biomedical discoveries explored in, Ethnobotany of Tuberculosis in Laos, stresses the importance of conserving and sustaining our natural ecosystems for medicinal preservation and utilization.
Автор: Frederick Marcus Название: Bioinformatics and Systems Biology ISBN: 3642097065 ISBN-13(EAN): 9783642097065 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research.
Автор: R. R. Mohler; A. Ruberti Название: Variable Structure Systems with Application to Economics and Biology ISBN: 3540073906 ISBN-13(EAN): 9783540073901 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The proceedings of the Second US-Italy Seminar on Variable Structure Systems is published in this volume.
Автор: Miguel A. Aon; Valdur Saks; Uwe Schlattner Название: Systems Biology of Metabolic and Signaling Networks ISBN: 3662508354 ISBN-13(EAN): 9783662508350 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Starting with historical roots, this work explores the systems biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Автор: Heiko Enderling; Nava Almog; Lynn Hlatky Название: Systems Biology of Tumor Dormancy ISBN: 1489998829 ISBN-13(EAN): 9781489998828 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume is based on the Workshop on Systems Biology of Tumor Dormancy meeting, held July 25th to July 28th, 2011.
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