Computational Creativity Research: Towards Creative Machines, Tarek R. Besold; Marco Schorlemmer; Alan Smaill

Автор: Tony Veale; Am?lcar Cardoso
Название: Computational Creativity
ISBN: 3319436082 ISBN-13(EAN): 9783319436081
Издательство: Springer
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Цена: 121110.00 T
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Описание: Computational creativity is an emerging field of research within AI that focuses on the capacity of machines to both generate and evaluate novel outputs that would, if produced by a human, be considered creative. This book is intended to be a canonical text for this new discipline, through which researchers and students can absorb the philosophy of the field and learn its methods. After a comprehensive introduction to the idea of systematizing creativity the contributions address topics such as autonomous intentionality, conceptual blending, literature mining, computational design, models of novelty, evaluating progress in related research, computer-supported human creativity and human-supported computer creativity, common-sense knowledge, and models of social creativity.Products of this research will have real consequences for the worlds of entertainment, culture, science, education, design, and art, in addition to artificial intelligence, and the book will be of value to practitioners and students in all these domains.

Автор: Bernard Testa
Название: Pharmacokinetic Optimization in Drug Research: Biological, Physicochemical, and Computational Strategies
ISBN: 3906390225 ISBN-13(EAN): 9783906390222
Издательство: Wiley
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Цена: 153120.00 T
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Описание: In this age of combinatorial chemistry and high-throughput technologies, bioactive compounds called hits are discovered by the thousands. However, the road that leads from hits to lead compounds and then to pharmacokinetically optimized clinical and drug candidates is very long indeed. As a result, the screening, design, and optimization of pharmacokinetic properties has become the bottleneck and a major challenge in drug research. To shorten the time-consuming develop-ment and high rate of attrition of active compounds ultimately doomed by hidden pharmacokinetic defects, drug researchers are coming to incorporate structure-permeation, structure-distribution, structure-metabolism, and structure-toxicity relations into drug-design strategies. To this end, powerful biological, physicochemical, and computational approaches are being developed whose objectives are to increase the clinical relevance of drug design, and to eliminate as soon as possible compounds with unfavorable physicochemical properties and pharmacokinetic profiles. Toxicological issues are also of utmost importance in this paradigm. There was, hence, an urgent need for a book covering this field in an authoritative, didactic, comprehensive, factual, and conceptual manner. In this work of unique breadth and depth, international authorities and practicing experts from academia and industry present the most modern biological, physicochemical, and computational strategies to optimize gastrointestinal absorption, protein binding and distribution, brain permeation, and metabolic profile. The biological strategies emphasized in the book include cell cultures and high-throughput screens. The physicochemical strategies focus on the determination and interpretation of solubility, lipophilicity, and related molecular properties as factors and predictors of pharmacokinetic bahavior. Particular attention is paid to the lipophilicity profiles of ionized compounds, to lipophicity measurements in anisotropic media (liposomes/water, IAM columns), and to permeability across artificial membranes. Computational strategies comprise virtual screening, molecular modelling, lipophilicity, and H-bonding fields and their importance for structure-disposition relations. This book is both about theoretical and technological breakthroughs. Thus, molecular properties are contemplated from a dual perspective, namely a) their interpretation in biological and/or physicochemical terms, and b) their value in screening, lead optimization, and drug-candidate selection. In addition to its 33 chapters, the book includes a CD-ROM containing the invited lectures, oral communications and posters (in full version) presented at the Second LogP Symposium, 'Lipophilicity in Drug Disposition -- Practical and Computational Approaches to Molecular Properties Related to Drug Permeation, Disposition and Metabolism', held at the University of Lausanne in March 2000.

Автор: Michael Filimowicz
Название: Teaching Computational Creativity
ISBN: 1107138043 ISBN-13(EAN): 9781107138049
Издательство: Cambridge Academ
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Описание: This book examines the new interdisciplinary pedagogies of today`s coding-intensive interactive media and design curricula. It covers a comprehensive overview of educational practices related in fields such as digital media, 3D printing, agile development, physical computing, games, dance, collaboration, teacher education and online learning.

Автор: Jacques Periaux; Stephane Lanteri; Panagiotis Chav
Название: Optimum Aerodynamic Design & Parallel Navier-Stokes Computations ECARP — European Computational Aerodynamics Research Project
ISBN: 3322901955 ISBN-13(EAN): 9783322901958
Издательство: Springer
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Цена: 113190.00 T
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Описание: This volume entitled "European Computational Aerodynamics Research Project (ECARP)" contains the contributions of partners presented in two work- shops focused on the following areas: Task 3 on Optimum Design and Task 4.2 on Navier Stokes Flow algorithms on Massively Parallel Processors. ECARP has been supported by the European Union (EU) through the Indus- trial and Materials Technology Programme, Area 3 Aeronautics, with the Third Research Framework Programme (1990-1994). Part A of this volume is focused on computational constrained optimization as a follow up of the EU research project" Optimum Design in Aerodynamics," (AERO-S9-0026) dealing with more viscous flow based real applications. It pro- vides the reader with a set of optimization tools and referenced data useful in modern aerodynamic design. Task 3 of the project entitled "Optimum Design" brought together 13 Euro- pean partners from the academic and industrial aeronautic oriented community showing state of the art expertise in traditional automated optimization software on current computer technology to improve the capability to optimize aircraft shapes.

Автор: Martin Vingron; Limsoon Wong
Название: Research in Computational Molecular Biology
ISBN: 3540788387 ISBN-13(EAN): 9783540788386
Издательство: Springer
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Цена: 83850.00 T
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Описание: Constitutes the refereed proceedings of the 12th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2008, held in Singapore, in March/April 2008.

Автор: Holzman
Название: Mathematical Programming for Operations Researchers and Computer Scientists
ISBN: 0824714997 ISBN-13(EAN): 9780824714994
Издательство: Taylor&Francis
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Цена: 255200.00 T
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Описание: This book covers the fundamentals of linear programming, extension of linear programming to discrete optimization methods, multi-objective functions, quadratic programming, geometric programming, and classical calculus methods for solving nonlinear programming problems.

Автор: Satoru Miyano; Jill Mesirov; Simon Kasif; Sorin Is
Название: Research in Computational Molecular Biology
ISBN: 3540258663 ISBN-13(EAN): 9783540258667
Издательство: Springer
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Цена: 111790.00 T
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Описание: This volume contains the papers presented at the 9th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2005), which was held in Cambridge, Massachusetts, on May 14-18, 2005.

Автор: S?ndor Suhai
Название: Theoretical and Computational Methods in Genome Research
ISBN: 1461377080 ISBN-13(EAN): 9781461377085
Издательство: Springer
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Цена: 46570.00 T
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Описание: Proceedings of an international symposium held in Heidelberg, Germany, May 25-27, 1996

Автор: Ahamed
Название: Computational Framework for Knowledge - Integrated Behavior of Machines
ISBN: 0470446862 ISBN-13(EAN): 9780470446867
Издательство: Wiley
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Цена: 173130.00 T
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Описание: "Intriguing... [filled with] new ideas about overarching intellectual themes that govern our technologies and our society. " - Nikil Jayant , Eminent Scholar, Georgia Research Alliance "Dr. Ahamed is correct in observing that `silicon and glass have altered the rhythm of mind` and that computers need to be more `human. `" - Bishnu S.

Автор: Jacek M. Zurada; Gary G. Yen; Jun Wang
Название: Computational Intelligence: Research Frontiers
ISBN: 3540688587 ISBN-13(EAN): 9783540688587
Издательство: Springer
Цена: 69870.00 T
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Автор: Bonnie Berger
Название: Research in Computational Molecular Biology
ISBN: 3642126820 ISBN-13(EAN): 9783642126826
Издательство: Springer
Цена: 97820.00 T
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Описание: This volume contains the papers presented at RECOMB 2010: the 14th Annual International Conference on Research in Computational Molecular Biology held in Lisbon, Portugal, during April 25-28, 2010. The RECOMB conference series was started in 1997 by Sorin Istrail, Pavel Pevzner, and Michael Waterman. RECOMB 2010 was hosted by INESC-ID and Instituto Superior Tecnico, or- nized by a committee chaired by Arlindo Oliveira and took place at the Int- national Fair of Lisbon Meeting Centre. This year, 36 papers were accepted for presentation out of 176 submissions. The papers presented were selected by the Program Committee (PC) assisted by a number of external reviewers. Each paper was reviewed by three members of the PC, or by external reviewers, and there was an extensive Web-based discussion over a period of two weeks, leading to the ?nal decisions. RECOMB 2010 also introduced a Highlights Track, in which six additional presentations by senior authors were chosen from papers published in 2009. The RECOMB conferenceseriesiscloselyassociatedwiththeJournalofComputational Biology, which traditionally publishes special issues devoted to presenting full versions of selected conference papers.